JP2014514326A5 - - Google Patents

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JP2014514326A5
JP2014514326A5 JP2014508181A JP2014508181A JP2014514326A5 JP 2014514326 A5 JP2014514326 A5 JP 2014514326A5 JP 2014508181 A JP2014508181 A JP 2014508181A JP 2014508181 A JP2014508181 A JP 2014508181A JP 2014514326 A5 JP2014514326 A5 JP 2014514326A5
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JP
Japan
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tic10
trail
composition
subject
cells
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JP2014508181A
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Japanese (ja)
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JP6132833B2 (ja
JP2014514326A (ja
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Priority claimed from PCT/US2012/035831 external-priority patent/WO2012149546A2/en
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Publication of JP2014514326A5 publication Critical patent/JP2014514326A5/ja
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JP2014508181A 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導 Active JP6132833B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161480743P 2011-04-29 2011-04-29
US61/480,743 2011-04-29
PCT/US2012/035831 WO2012149546A2 (en) 2011-04-29 2012-04-30 Small molecule trail gene induction by normal and tumor cells as an anticancer therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016142086A Division JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Publications (3)

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JP2014514326A JP2014514326A (ja) 2014-06-19
JP2014514326A5 true JP2014514326A5 (cg-RX-API-DMAC10.html) 2014-12-18
JP6132833B2 JP6132833B2 (ja) 2017-05-24

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JP2014508181A Active JP6132833B2 (ja) 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2023033777A Active JP7600286B2 (ja) 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Family Applications After (6)

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JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2023033777A Active JP7600286B2 (ja) 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子ｔｒａｉｌ遺伝子誘導

Country Status (18)

Country Link
US (9) US8673923B2 (cg-RX-API-DMAC10.html)
EP (4) EP3679934B1 (cg-RX-API-DMAC10.html)
JP (7) JP6132833B2 (cg-RX-API-DMAC10.html)
CA (1) CA2832342C (cg-RX-API-DMAC10.html)
CY (1) CY1123010T1 (cg-RX-API-DMAC10.html)
DK (3) DK3679934T3 (cg-RX-API-DMAC10.html)
ES (3) ES3063552T3 (cg-RX-API-DMAC10.html)
FI (2) FI3679934T3 (cg-RX-API-DMAC10.html)
HR (3) HRP20200636T1 (cg-RX-API-DMAC10.html)
HU (2) HUE049207T2 (cg-RX-API-DMAC10.html)
LT (3) LT4335511T (cg-RX-API-DMAC10.html)
MX (2) MX365365B (cg-RX-API-DMAC10.html)
PL (3) PL2701708T3 (cg-RX-API-DMAC10.html)
PT (3) PT3679934T (cg-RX-API-DMAC10.html)
RS (3) RS67757B1 (cg-RX-API-DMAC10.html)
SI (3) SI4335511T1 (cg-RX-API-DMAC10.html)
SM (3) SMT202400421T1 (cg-RX-API-DMAC10.html)
WO (1) WO2012149546A2 (cg-RX-API-DMAC10.html)

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US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
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US9688679B2 (en) 2013-03-13 2017-06-27 Oncoceutics, Inc. 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-A]pyrido[3,4-E]pyrimidin-5 (1H)-one, salts thereof and methods of using the same in combination therapy
WO2015073072A1 (en) * 2013-11-15 2015-05-21 Oncoceutics, Inc. 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one
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SMT201900291T1 (it) * 2013-11-15 2019-07-11 Oncoceutics Inc 7-benzil-4-(2-metilbenzil)-2,4,6,7,8,9-esaidriomidazo[1,2-a]pirido[3,4-e]pirimidin-5(1h)-one, suoi sali e metodi d'uso
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
WO2015138638A1 (en) 2014-03-11 2015-09-17 Theraly Pharmaceuticals, Inc. Long acting trail receptor agonists for treatment of autoimmune diseases
HUE069651T2 (hu) 2014-03-31 2025-03-28 Scripps Research Inst Farmakofór TRAIL indukcióra
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
SMT202500087T1 (it) 2015-01-30 2025-03-12 Oncoceutics Inc Derivati di 7-benzil-4-(2-metilbenzil)-2,4,6,7,8,9-esaidroimidazo[1,2-a]pirido[3,4-e]pirimidin-5(1h)-one, loro sali e loro uso in terapia
WO2016160918A1 (en) 2015-03-31 2016-10-06 The University Of North Carolina At Chapel Hill Delivery vehicles for stem cells and uses thereof
CN104860948B (zh) * 2015-05-15 2017-09-26 南京盖特医药技术有限公司 咪唑并嘧啶酮类化合物及其制备方法和应用
US11007251B2 (en) 2015-12-17 2021-05-18 The Johns Hopkins University Ameliorating systemic sclerosis with death receptor agonists
WO2017132661A2 (en) 2016-01-29 2017-08-03 Oncoceutics, Inc. G protein-coupled receptor (gpcr) modulation by imipridones
CN109195620B (zh) 2016-04-07 2022-06-28 约翰霍普金斯大学 用死亡受体激动剂治疗胰腺炎和疼痛的组合物和方法
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
US11767353B2 (en) 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
CN119997956A (zh) 2022-08-05 2025-05-13 奇默里克斯公司 药物组合物及其用于治疗胶质瘤的用途
US20260191864A1 (en) * 2022-11-10 2026-07-09 Emory University Uses of Hydroimidazopyridopyrimidinone Derivatives for Managing Aneurysms or Other Vascular Conditions or Diseases

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RS67757B1 (sr) 2011-04-29 2026-03-31 Penn State Res Found Indukcija malim molekulom trail gena u normalnim i tumorskim ćelijama kao antikancerska terapija
PL2968294T3 (pl) 2013-03-13 2019-10-31 Oncoceutics Inc 7-Benzylo-10-(2-metylobenzylo)-2,6,7,8,9,10-heksahydroimidazo[1,2-a]pirydo[4,3-d]pirymidyn-5(3H)-on do zastosowania w leczeniu nowotworu

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