JP2014510699A5 - - Google Patents
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- Publication number
- JP2014510699A5 JP2014510699A5 JP2013543901A JP2013543901A JP2014510699A5 JP 2014510699 A5 JP2014510699 A5 JP 2014510699A5 JP 2013543901 A JP2013543901 A JP 2013543901A JP 2013543901 A JP2013543901 A JP 2013543901A JP 2014510699 A5 JP2014510699 A5 JP 2014510699A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- peptide
- tumor
- peptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 230000000259 anti-tumor effect Effects 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 208000003174 Brain Neoplasms Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 206010038389 Renal cancer Diseases 0.000 claims 2
- 230000005907 cancer growth Effects 0.000 claims 2
- 230000004709 cell invasion Effects 0.000 claims 2
- 230000012292 cell migration Effects 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 208000005017 glioblastoma Diseases 0.000 claims 2
- 201000010536 head and neck cancer Diseases 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 201000010982 kidney cancer Diseases 0.000 claims 2
- 201000007270 liver cancer Diseases 0.000 claims 2
- 208000014018 liver neoplasm Diseases 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 201000002313 intestinal cancer Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42285610P | 2010-12-14 | 2010-12-14 | |
| US61/422,856 | 2010-12-14 | ||
| PCT/IB2011/003053 WO2012080822A2 (en) | 2010-12-14 | 2011-12-14 | Antitumor peptide derived from a complementarity determining region of a humanized monoclonal antibody to napi2b transporter |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014510699A JP2014510699A (ja) | 2014-05-01 |
| JP2014510699A5 true JP2014510699A5 (cg-RX-API-DMAC7.html) | 2015-02-05 |
| JP6087289B2 JP6087289B2 (ja) | 2017-03-01 |
Family
ID=46245158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543901A Active JP6087289B2 (ja) | 2010-12-14 | 2011-12-14 | Ｎａｐｉ２ｂ輸送体に対するヒト化モノクローナル抗体の相補性決定領域に由来する抗腫瘍ペプチド |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9193797B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2654769B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6087289B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013015001B1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO6721014A2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2804476T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2654769T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012080822A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105828840B (zh) * | 2013-12-16 | 2020-08-04 | 基因泰克公司 | 1-(氯甲基)-2,3-二氢-1H-苯并[e]吲哚二聚体抗体-药物缀合物化合物及使用和治疗方法 |
| CN105491524B (zh) * | 2015-12-11 | 2019-04-26 | 小米科技有限责任公司 | 一种确定目标便携设备位置的方法和装置 |
| EP3648792A4 (en) * | 2017-07-01 | 2021-07-21 | Recepta Biopharma S.A. | IMMUNOMODULATOR PEPTIDES AND METHODS FOR MODULATING THE IMMUNE SYSTEM IN A SUBJECT |
| JP7279026B2 (ja) * | 2017-09-20 | 2023-05-22 | メルサナ セラピューティクス インコーポレイテッド | Ｎａｐｉ２ｂ標的化療法に対する応答を予測するための組成物および方法 |
| CN116194138A (zh) | 2020-08-07 | 2023-05-30 | 博德研究所 | 治疗性靶向癌症中经由xpr1:kidins220蛋白质复合物的磷酸盐调节异常 |
| KR102822203B1 (ko) | 2020-12-29 | 2025-06-18 | 삼성전자주식회사 | 전력 공급 장치를 이용하여 오디오 출력 장치를 찾는 방법 및 그 전력 공급 장치 |
| CN116514926B (zh) * | 2023-06-25 | 2023-08-29 | 烟台药物研究所 | 一种抗肿瘤阳离子两亲肽及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9108652D0 (en) * | 1991-04-23 | 1991-06-12 | Antisoma Ltd | Immunoreactive compounds |
| AU684348B2 (en) * | 1994-06-07 | 1997-12-11 | Nihon Medi-Physics Co., Ltd. | Tumor affinity peptide, and radioactive diagnostic agent and adioactive therapeutic agent containing the peptide |
| US6689753B1 (en) | 1999-11-05 | 2004-02-10 | Axonyx, Inc. | β sheet breaker peptide analogs that inhibit β pleated sheet formation in amyloid β-peptide |
| WO2005040219A1 (en) * | 2003-10-28 | 2005-05-06 | Novo Nordisk A/S | Laminin-5 gamma2-binding peptides, related compositions, and use thereof |
| WO2009097128A1 (en) * | 2008-01-29 | 2009-08-06 | Ludwig Institute For Cancer Research Ltd. | Membrane transporter napi2b (slc34a2) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy |
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2011
- 2011-12-14 EP EP11849571.2A patent/EP2654769B1/en active Active
- 2011-12-14 US US13/991,688 patent/US9193797B2/en active Active
- 2011-12-14 WO PCT/IB2011/003053 patent/WO2012080822A2/en not_active Ceased
- 2011-12-14 PT PT118495712T patent/PT2654769T/pt unknown
- 2011-12-14 ES ES11849571T patent/ES2804476T3/es active Active
- 2011-12-14 BR BR112013015001-7A patent/BR112013015001B1/pt active IP Right Grant
- 2011-12-14 JP JP2013543901A patent/JP6087289B2/ja active Active
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2013
- 2013-06-14 CO CO13142398A patent/CO6721014A2/es unknown
-
2015
- 2015-10-27 US US14/924,003 patent/US9896512B2/en active Active