JP2014509325A5 - - Google Patents
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- Publication number
- JP2014509325A5 JP2014509325A5 JP2013555876A JP2013555876A JP2014509325A5 JP 2014509325 A5 JP2014509325 A5 JP 2014509325A5 JP 2013555876 A JP2013555876 A JP 2013555876A JP 2013555876 A JP2013555876 A JP 2013555876A JP 2014509325 A5 JP2014509325 A5 JP 2014509325A5
- Authority
- JP
- Japan
- Prior art keywords
- monovalent antibody
- antibody according
- seq
- set forth
- monovalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11156416.7 | 2011-03-01 | ||
| EP11156416 | 2011-03-01 | ||
| US201161448827P | 2011-03-03 | 2011-03-03 | |
| US61/448,827 | 2011-03-03 | ||
| PCT/EP2012/053539 WO2012117067A1 (en) | 2011-03-01 | 2012-03-01 | Antagonistic dr3 ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014509325A JP2014509325A (ja) | 2014-04-17 |
| JP2014509325A5 true JP2014509325A5 (https=) | 2015-04-23 |
| JP6215056B2 JP6215056B2 (ja) | 2017-10-18 |
Family
ID=44210048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013555876A Expired - Fee Related JP6215056B2 (ja) | 2011-03-01 | 2012-03-01 | 拮抗性ｄｒ３リガンド |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9737612B2 (https=) |
| EP (1) | EP2681237A1 (https=) |
| JP (1) | JP6215056B2 (https=) |
| KR (1) | KR20140043720A (https=) |
| CN (1) | CN103517918A (https=) |
| BR (1) | BR112013022052A2 (https=) |
| CA (1) | CA2828464A1 (https=) |
| IL (1) | IL227535A0 (https=) |
| MX (1) | MX2013009859A (https=) |
| RU (1) | RU2013141079A (https=) |
| WO (1) | WO2012117067A1 (https=) |
| ZA (1) | ZA201306110B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2972330A4 (en) * | 2013-03-15 | 2016-10-26 | Alder Biopharmaceuticals Inc | PROTOCOL FOR THE IDENTIFICATION AND ISOLATION OF ANTIGEN-SPECIFIC B-CELLS AND FOR THE PREPARATION OF ANTIBODIES FOR DESIRED ANTIGENES |
| WO2015036553A1 (en) | 2013-09-16 | 2015-03-19 | Novo Nordisk Health Care Ag | Thiol functionalized polymers |
| US9416197B2 (en) | 2013-11-01 | 2016-08-16 | Ibc Pharmaceuticals, Inc. | Bispecific antibodies that neutralize both TNF-α and IL-6: novel therapeutic agent for autoimmune disease |
| SG11201608253XA (en) | 2014-04-04 | 2016-10-28 | Kyowa Hakko Kirin Co Ltd | Anti-death receptor 3 (dr3) antagonistic antibodies with reduced agonistic activity |
| EP3137495A4 (en) * | 2014-04-28 | 2017-11-15 | The National Institute for Biotechnology in the Negev, Ltd. | Variants of dr3 and use thereof |
| EP3572502B1 (en) * | 2017-01-20 | 2023-01-11 | Kyoto University | Method for producing cd8alpha +beta + cytotoxic t cells |
| EP3860653A1 (en) | 2018-10-05 | 2021-08-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and systems for controlling the agonistic properties of antibody variable domains by light |
| CN111808183B (zh) * | 2020-07-25 | 2022-07-08 | 北京吉尔麦迪生物医药科技有限公司 | 一种靶向CD47的高亲和力SIRPα突变体及其融合蛋白 |
| US20250249278A1 (en) | 2022-04-14 | 2025-08-07 | Institut National de la Santé et de la Recherche Médicale | Methods for controlling the tumor cell killing by light |
| EP4501966A4 (en) * | 2022-06-17 | 2025-10-22 | Selecxine Inc | ANTIBODY SPECIFICALLY BINDING TO HUMAN DR3 AND ITS USE |
| CN116223818B (zh) * | 2023-05-09 | 2023-07-21 | 四川大学华西医院 | Dr3蛋白检测试剂在制备筛查aecopd的试剂盒的用途及筛查aecopd的试剂盒 |
| CN120399074B (zh) * | 2023-06-02 | 2025-12-30 | 安徽金百奥生物科技有限公司 | 一种与人dr3胞外域高亲和力的纳米抗体 |
| CN121843714A (zh) | 2023-08-11 | 2026-04-10 | 派拉冈医疗公司 | Tl1a结合抗体及使用方法 |
| GB202315963D0 (en) | 2023-10-18 | 2023-11-29 | Cancer Research Tech Ltd | Binding molecules |
| WO2025158389A1 (en) | 2024-01-24 | 2025-07-31 | Shattuck Labs, Inc. | Antibodies that bind tnfrsf25 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1241944C (zh) | 1995-09-11 | 2006-02-15 | 协和发酵工业株式会社 | 抗人白介素－5受体α链的抗体 |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| CA2249206A1 (en) | 1996-04-01 | 1997-10-09 | Genentech, Inc. | Apo-2li and apo-3 apoptosis polypeptides |
| CN101070344A (zh) | 1998-04-30 | 2007-11-14 | 泰诺士公司 | G－csf受体兴奋剂抗体及其筛选方法 |
| FR2780062B1 (fr) | 1998-06-17 | 2000-07-28 | Rhone Poulenc Rorer Sa | Anticorps monoclonaux diriges contre la proteine g3bp, et leurs utilisations |
| CA2371114A1 (en) * | 1999-04-22 | 2000-11-02 | Human Genome Sciences, Inc. | Death domain containing receptors |
| CA2391530A1 (en) * | 1999-11-19 | 2001-05-25 | Thomas V. Tittle | Tr3-specific binding agents and methods for their use |
| US6638906B1 (en) * | 1999-12-13 | 2003-10-28 | Nobex Corporation | Amphiphilic polymers and polypeptide conjugates comprising same |
| US7148061B2 (en) | 2000-02-11 | 2006-12-12 | The United States Of America As Represented By The Department Of Health And Human Services | Identification of a novel domain in the tumor necrosis factor receptor family that mediates pre-ligand receptor assembly and function |
| WO2002040680A2 (en) | 2000-11-17 | 2002-05-23 | The Burnham Institute | Death domain proteins |
| US20040234524A1 (en) | 2001-04-05 | 2004-11-25 | Toshimitsu Uede | Anti-osteopontin antibody and use thereof |
| EP2042196B1 (en) | 2001-10-10 | 2016-07-13 | ratiopharm GmbH | Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF) |
| KR100499989B1 (ko) | 2002-12-27 | 2005-07-07 | 네오바이오다임 주식회사 | 아사이알로 α1-산 당단백질에 대한 단일클론 항체, 이 항체를 포함하는 아사이알로 α1-산 당단백질에 대한 단일클론 항체, 이 항체를 포함하는 면역크로마토그래피 스트립 및 이 스트립를 이용한 아사이알로 α1-산 당단백질 측정방법 |
| US20090317388A1 (en) * | 2005-05-25 | 2009-12-24 | Linda Burkly | Tl1a in treatment of disease |
| JP5164167B2 (ja) * | 2005-08-30 | 2013-03-13 | ユニバーシティー オブ マイアミ | 免疫調節性腫瘍壊死因子受容体２５（ｔｎｆｒ２５）のアゴニスト、アンタゴニスト及び免疫毒素 |
| US20110195048A1 (en) | 2008-10-08 | 2011-08-11 | Podack Eckhard R | Regulation of lymphocytes and uses therefor |
| WO2011106707A2 (en) * | 2010-02-26 | 2011-09-01 | Human Genome Sciences, Inc. | Antibodies that specifically bind to dr3 |
-
2012
- 2012-03-01 MX MX2013009859A patent/MX2013009859A/es unknown
- 2012-03-01 US US13/982,617 patent/US9737612B2/en not_active Expired - Fee Related
- 2012-03-01 EP EP12707996.0A patent/EP2681237A1/en not_active Withdrawn
- 2012-03-01 CA CA2828464A patent/CA2828464A1/en not_active Withdrawn
- 2012-03-01 CN CN201280011136.1A patent/CN103517918A/zh active Pending
- 2012-03-01 JP JP2013555876A patent/JP6215056B2/ja not_active Expired - Fee Related
- 2012-03-01 RU RU2013141079/10A patent/RU2013141079A/ru unknown
- 2012-03-01 KR KR1020137021269A patent/KR20140043720A/ko not_active Withdrawn
- 2012-03-01 WO PCT/EP2012/053539 patent/WO2012117067A1/en not_active Ceased
- 2012-03-01 BR BR112013022052A patent/BR112013022052A2/pt not_active IP Right Cessation
-
2013
- 2013-07-18 IL IL227535A patent/IL227535A0/en unknown
- 2013-08-14 ZA ZA2013/06110A patent/ZA201306110B/en unknown
- 2013-08-23 US US13/974,275 patent/US8765130B2/en active Active
-
2014
- 2014-05-01 US US14/267,028 patent/US9713644B2/en not_active Expired - Fee Related
-
2017
- 2017-07-05 US US15/641,611 patent/US20170305994A1/en not_active Abandoned
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