JP2014506900A5 - - Google Patents
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- Publication number
- JP2014506900A5 JP2014506900A5 JP2013555798A JP2013555798A JP2014506900A5 JP 2014506900 A5 JP2014506900 A5 JP 2014506900A5 JP 2013555798 A JP2013555798 A JP 2013555798A JP 2013555798 A JP2013555798 A JP 2013555798A JP 2014506900 A5 JP2014506900 A5 JP 2014506900A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- tapentadol
- criteria
- hcl
- result
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KWTWDQCKEHXFFR-SMDDNHRTSA-N tapentadol Chemical compound CN(C)C[C@H](C)[C@@H](CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-SMDDNHRTSA-N 0.000 description 5
- 229960005126 tapentadol Drugs 0.000 description 5
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449329P | 2011-03-04 | 2011-03-04 | |
| US61/449,329 | 2011-03-04 | ||
| EP11003603.5 | 2011-05-03 | ||
| EP11003603 | 2011-05-03 | ||
| PCT/EP2012/000906 WO2012119729A1 (en) | 2011-03-04 | 2012-03-02 | Semisolid aqueous pharmaceutical composition containing tapentadol |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016200663A Division JP6259042B2 (ja) | 2011-03-04 | 2016-10-12 | タペンタドールを含む半固形の水性医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014506900A JP2014506900A (ja) | 2014-03-20 |
| JP2014506900A5 true JP2014506900A5 (OSRAM) | 2016-09-01 |
| JP6027549B2 JP6027549B2 (ja) | 2016-11-16 |
Family
ID=44652117
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013555798A Expired - Fee Related JP6027549B2 (ja) | 2011-03-04 | 2012-03-02 | タペンタドールを含む半固形の水性医薬組成物 |
| JP2016200663A Expired - Fee Related JP6259042B2 (ja) | 2011-03-04 | 2016-10-12 | タペンタドールを含む半固形の水性医薬組成物 |
| JP2017228602A Expired - Fee Related JP6670283B2 (ja) | 2011-03-04 | 2017-11-29 | タペンタドールを含む半固形の水性医薬組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016200663A Expired - Fee Related JP6259042B2 (ja) | 2011-03-04 | 2016-10-12 | タペンタドールを含む半固形の水性医薬組成物 |
| JP2017228602A Expired - Fee Related JP6670283B2 (ja) | 2011-03-04 | 2017-11-29 | タペンタドールを含む半固形の水性医薬組成物 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US9446008B2 (OSRAM) |
| EP (3) | EP3290029B1 (OSRAM) |
| JP (3) | JP6027549B2 (OSRAM) |
| KR (2) | KR102039320B1 (OSRAM) |
| CN (1) | CN103501774A (OSRAM) |
| AU (2) | AU2012224954C1 (OSRAM) |
| BR (1) | BR112013022556A8 (OSRAM) |
| CA (1) | CA2828637C (OSRAM) |
| CY (1) | CY1119725T1 (OSRAM) |
| DK (1) | DK2680834T3 (OSRAM) |
| EA (2) | EA025194B1 (OSRAM) |
| ES (2) | ES2910085T3 (OSRAM) |
| HR (1) | HRP20171836T1 (OSRAM) |
| HU (1) | HUE037491T2 (OSRAM) |
| IL (2) | IL227826B (OSRAM) |
| LT (1) | LT2680834T (OSRAM) |
| MX (2) | MX344473B (OSRAM) |
| NO (1) | NO2680834T3 (OSRAM) |
| PL (1) | PL2680834T3 (OSRAM) |
| PT (2) | PT2680834T (OSRAM) |
| RS (1) | RS56692B1 (OSRAM) |
| SI (1) | SI2680834T1 (OSRAM) |
| WO (1) | WO2012119729A1 (OSRAM) |
| ZA (1) | ZA201306480B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012224954C1 (en) | 2011-03-04 | 2017-04-06 | Grünenthal GmbH | Semisolid aqueous pharmaceutical composition containing tapentadol |
| EP3597182A1 (en) | 2011-03-04 | 2020-01-22 | Grünenthal GmbH | Aqueous pharmaceutical formulation of tapentadol for oral administration |
| US9395306B2 (en) | 2011-08-05 | 2016-07-19 | Halliburton Energy Services, Inc. | Methods for monitoring fluids within or produced from a subterranean formation during acidizing operations using opticoanalytical devices |
| US8997860B2 (en) | 2011-08-05 | 2015-04-07 | Halliburton Energy Services, Inc. | Methods for monitoring the formation and transport of a fracturing fluid using opticoanalytical devices |
| US8619256B1 (en) | 2012-09-14 | 2013-12-31 | Halliburton Energy Services, Inc. | Systems and methods for monitoring the properties of a fluid cement composition in a flow path |
| US20140076550A1 (en) | 2012-09-14 | 2014-03-20 | Halliburton Energy Services, Inc. | Systems and Methods for Detecting Microannulus Formation and Remediation |
| US9228940B2 (en) | 2012-09-14 | 2016-01-05 | Halliburton Energy Services, Inc. | Systems, methods, and apparatuses for in situ monitoring of cement fluid compositions and setting processes thereof |
| WO2015014980A1 (en) * | 2013-08-02 | 2015-02-05 | Ratiopharm Gmbh | Composition comprising tapentadol in a dissolved form |
| EP2845625A1 (en) | 2013-09-04 | 2015-03-11 | Grünenthal GmbH | Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome |
| CN107847471A (zh) * | 2015-03-27 | 2018-03-27 | 格吕伦塔尔有限公司 | 他喷他多肠胃外给药的稳定制剂 |
| PE20190908A1 (es) | 2016-09-23 | 2019-06-26 | Gruenenthal Chemie | Formulacion estable para la administracion parenteral de tapentadol |
| US20210290536A1 (en) * | 2018-07-24 | 2021-09-23 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Topical emulsion of an anticholinergic compound |
| US12447119B2 (en) | 2019-03-18 | 2025-10-21 | Sunstar Americas, Inc. | Oral care composition |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4775678A (en) * | 1984-10-01 | 1988-10-04 | Schering Corporation | Clotrimazole cream |
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| US6183758B1 (en) * | 1998-01-29 | 2001-02-06 | Highland Laboratories, Inc. | Phytochemicals, nutrients & medication absorption &/or treatment |
| US6399087B1 (en) | 2000-12-20 | 2002-06-04 | Amphastar Pharmaceuticals, Inc. | Propofol formulation with enhanced microbial inhibition |
| DE10109763A1 (de) | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| US20050176790A1 (en) | 2001-02-28 | 2005-08-11 | Johannes Bartholomaus | Pharmaceutical salts |
| PE20030527A1 (es) | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
| AU2003225837B2 (en) | 2002-03-15 | 2008-11-06 | Forest Laboratories Holdings Limited | NE and 5-HT reuptake inhibitors for treating visceral pain syndromes |
| US20030191187A1 (en) | 2002-04-01 | 2003-10-09 | Lee Fang Yu | Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same |
| AU2003275329B2 (en) | 2002-09-13 | 2008-04-03 | Cydex Pharmaceuticals, Inc. | Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin |
| US20040180915A1 (en) | 2003-03-14 | 2004-09-16 | Xanodyne Pharmacal, Inc. | Methadone-containing compositions for parenteral administration and method of use thereof |
| WO2005112926A1 (en) | 2004-05-17 | 2005-12-01 | Pharmacofore, Inc. | Compositions and methods for treating or preventing pain |
| ES2291780T3 (es) | 2004-06-28 | 2008-03-01 | Grunenthal Gmbh | Formas cristalinas del clorhidrato de (-)-(1r,2r)-3-(3-dimetilamino-1-etil-2-metilpropil)fenol. |
| BRPI0513300B1 (pt) | 2004-07-01 | 2018-11-06 | Gruenenthal Gmbh | forma farmacêutica oral, protegida frente ao abuso, contendo (1r, 2r)-3-(3-dimetilamino-1-etil-2- metil-lpropil)-fenol |
| AU2006239313A1 (en) | 2005-04-28 | 2006-11-02 | Najib Babul | Methods and compositions for treating pain |
| TWI329334B (en) | 2005-12-02 | 2010-08-21 | Chung Shan Inst Of Science | Manufacture method of electromagnetic interference layer for the plasma display panel |
| WO2007127158A2 (en) * | 2006-04-25 | 2007-11-08 | Croda, Inc | Modification of percutaneous absorption of topically active materials |
| RU2465263C2 (ru) | 2006-04-28 | 2012-10-27 | Грюненталь Гмбх | Фармацевтическая комбинация, включающая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и нестероидный противовоспалительный препарат |
| BRPI0710682B8 (pt) | 2006-04-28 | 2021-05-25 | Gruenenthal Gmbh | combinação farmacêutica compreendendo 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol e paracetamol |
| PT2046726E (pt) | 2006-07-24 | 2010-04-15 | Janssen Pharmaceutica Nv | Preparação da (2r,3r)-3-(3-metoxifenil)-n,n,2- trimetilpentanamina |
| DE102007012165A1 (de) | 2007-03-12 | 2008-09-18 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes |
| EP1985292A1 (en) | 2007-04-23 | 2008-10-29 | Grünenthal GmbH | Titration of tapentadol |
| PL2596784T3 (pl) * | 2007-11-23 | 2017-06-30 | Grünenthal GmbH | Kompozycje tapentadolu |
| NZ586792A (en) | 2008-01-25 | 2012-09-28 | Gruenenthal Chemie | Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces |
| WO2010096045A1 (en) | 2008-10-30 | 2010-08-26 | Nectid, Inc. | Novel and potent tapentadol dosage forms |
| US20100227921A1 (en) | 2009-03-03 | 2010-09-09 | Shire Llc | Amino acid and peptide carbamate prodrugs of tapentadol and uses thereof |
| US20100272815A1 (en) * | 2009-04-28 | 2010-10-28 | Actavis Group Ptc Ehf | Amorphous form of tapentadol hydrochloride |
| WO2011083304A1 (en) * | 2010-01-05 | 2011-07-14 | Shire Llc | Prodrugs of opioids and uses thereof |
| US8652511B2 (en) * | 2010-03-30 | 2014-02-18 | Phosphagenics Limited | Transdermal delivery patch |
| GB201006200D0 (en) * | 2010-04-14 | 2010-06-02 | Ayanda As | Composition |
| US20120270848A1 (en) * | 2010-10-22 | 2012-10-25 | Galleon Pharmaceuticals, Inc. | Novel Compositions and Therapeutic Methods Using Same |
| AU2012224954C1 (en) | 2011-03-04 | 2017-04-06 | Grünenthal GmbH | Semisolid aqueous pharmaceutical composition containing tapentadol |
-
2012
- 2012-03-02 AU AU2012224954A patent/AU2012224954C1/en not_active Ceased
- 2012-03-02 ES ES20188822T patent/ES2910085T3/es active Active
- 2012-03-02 CA CA2828637A patent/CA2828637C/en not_active Expired - Fee Related
- 2012-03-02 KR KR1020187029861A patent/KR102039320B1/ko not_active Expired - Fee Related
- 2012-03-02 PL PL12710026T patent/PL2680834T3/pl unknown
- 2012-03-02 DK DK12710026.1T patent/DK2680834T3/en active
- 2012-03-02 HU HUE12710026A patent/HUE037491T2/hu unknown
- 2012-03-02 ES ES12710026.1T patent/ES2654407T3/es active Active
- 2012-03-02 SI SI201231143T patent/SI2680834T1/en unknown
- 2012-03-02 PT PT127100261T patent/PT2680834T/pt unknown
- 2012-03-02 WO PCT/EP2012/000906 patent/WO2012119729A1/en not_active Ceased
- 2012-03-02 HR HRP20171836TT patent/HRP20171836T1/hr unknown
- 2012-03-02 KR KR1020137026185A patent/KR101911362B1/ko not_active Expired - Fee Related
- 2012-03-02 US US13/410,837 patent/US9446008B2/en active Active
- 2012-03-02 EA EA201300988A patent/EA025194B1/ru not_active IP Right Cessation
- 2012-03-02 JP JP2013555798A patent/JP6027549B2/ja not_active Expired - Fee Related
- 2012-03-02 LT LTEP12710026.1T patent/LT2680834T/lt unknown
- 2012-03-02 PT PT201888229T patent/PT3766489T/pt unknown
- 2012-03-02 EA EA201600442A patent/EA033171B1/ru not_active IP Right Cessation
- 2012-03-02 NO NO12710026A patent/NO2680834T3/no unknown
- 2012-03-02 EP EP17189139.3A patent/EP3290029B1/en active Active
- 2012-03-02 RS RS20171334A patent/RS56692B1/sr unknown
- 2012-03-02 BR BR112013022556A patent/BR112013022556A8/pt not_active Application Discontinuation
- 2012-03-02 EP EP20188822.9A patent/EP3766489B1/en active Active
- 2012-03-02 EP EP12710026.1A patent/EP2680834B1/en active Active
- 2012-03-02 MX MX2013010100A patent/MX344473B/es active IP Right Grant
- 2012-03-02 CN CN201280011678.9A patent/CN103501774A/zh active Pending
- 2012-03-02 MX MX2016016703A patent/MX374468B/es unknown
-
2013
- 2013-08-06 IL IL227826A patent/IL227826B/en active IP Right Grant
- 2013-08-28 ZA ZA2013/06480A patent/ZA201306480B/en unknown
-
2016
- 2016-08-10 US US15/232,841 patent/US20160346229A1/en not_active Abandoned
- 2016-10-12 JP JP2016200663A patent/JP6259042B2/ja not_active Expired - Fee Related
-
2017
- 2017-01-04 AU AU2017200040A patent/AU2017200040B2/en not_active Ceased
- 2017-11-29 JP JP2017228602A patent/JP6670283B2/ja not_active Expired - Fee Related
-
2018
- 2018-01-03 CY CY20181100006T patent/CY1119725T1/el unknown
- 2018-01-10 US US15/867,330 patent/US20180133174A1/en not_active Abandoned
- 2018-03-26 IL IL258357A patent/IL258357A/en unknown
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