JP2014505056A5 - - Google Patents

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Publication number
JP2014505056A5
JP2014505056A5 JP2013548613A JP2013548613A JP2014505056A5 JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5 JP 2013548613 A JP2013548613 A JP 2013548613A JP 2013548613 A JP2013548613 A JP 2013548613A JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5
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JP
Japan
Prior art keywords
antibody
tlr4
immunologically active
active fragment
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013548613A
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English (en)
Japanese (ja)
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JP2014505056A (ja
JP6289098B2 (ja
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Publication date
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Priority claimed from PCT/US2012/020717 external-priority patent/WO2012096917A1/en
Publication of JP2014505056A publication Critical patent/JP2014505056A/ja
Publication of JP2014505056A5 publication Critical patent/JP2014505056A5/ja
Application granted granted Critical
Publication of JP6289098B2 publication Critical patent/JP6289098B2/ja
Active legal-status Critical Current
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JP2013548613A 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法 Active JP6289098B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161431191P 2011-01-10 2011-01-10
US61/431,191 2011-01-10
PCT/US2012/020717 WO2012096917A1 (en) 2011-01-10 2012-01-10 Anti-tlr4 antibodies and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017027473A Division JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法

Publications (3)

Publication Number Publication Date
JP2014505056A JP2014505056A (ja) 2014-02-27
JP2014505056A5 true JP2014505056A5 (enExample) 2015-02-26
JP6289098B2 JP6289098B2 (ja) 2018-03-07

Family

ID=46455425

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013548613A Active JP6289098B2 (ja) 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Country Status (7)

Country Link
US (4) US8734790B2 (enExample)
EP (2) EP3539987A1 (enExample)
JP (3) JP6289098B2 (enExample)
AU (2) AU2012205763B2 (enExample)
CA (1) CA2824060C (enExample)
ES (1) ES2721378T3 (enExample)
WO (1) WO2012096917A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2173381T1 (sl) * 2007-05-14 2014-01-31 Novimmune Sa Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami
JP6289098B2 (ja) * 2011-01-10 2018-03-07 ノビミューン エスアー 抗ｔｌｒ４抗体およびその使用法
HUE037613T2 (hu) * 2012-03-29 2018-09-28 Novimmune Sa Anti-TLR4 antitestek és azok felhasználása
EP3060250A1 (en) 2013-10-22 2016-08-31 NovImmune SA Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers
WO2015082716A1 (en) * 2013-12-06 2015-06-11 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
WO2017021552A1 (en) * 2015-08-06 2017-02-09 Novimmune Sa Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders
WO2017160599A1 (en) 2016-03-14 2017-09-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of cd300b antagonists to treat sepsis and septic shock
CN109481666B (zh) * 2018-12-21 2020-11-03 江苏省中医院 一种人体血液肿瘤pdx模型的建立方法
WO2021212222A1 (en) * 2020-04-20 2021-10-28 Edesa Biotech Research Inc. Compositions and methods for treatment of acute respiratory distress syndrome
WO2022112198A1 (en) 2020-11-24 2022-06-02 Worldwide Innovative Network Method to select the optimal immune checkpoint therapies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5151510A (en) 1990-04-20 1992-09-29 Applied Biosystems, Inc. Method of synethesizing sulfurized oligonucleotide analogs
US5624946A (en) * 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
MXPA05002514A (es) * 2002-09-06 2005-05-27 Amgen Inc Anticuerpo monoclonal anti-il-1r1 humano terapeutico.
ATE544783T1 (de) 2003-12-10 2012-02-15 Novimmune Sa Neutralisierende anti tlr4/md-2 antikörper und verfahren zu deren verwendung
US7312320B2 (en) 2003-12-10 2007-12-25 Novimmune Sa Neutralizing antibodies and methods of use thereof
US7674884B2 (en) 2003-12-10 2010-03-09 Novimmune S.A. Neutralizing antibodies and methods of use thereof
ES2689328T3 (es) * 2004-01-07 2018-11-13 Novartis Vaccines And Diagnostics, Inc. Anticuerpo monoclonal M-CSF-específico y usos del mismo
WO2007041218A2 (en) * 2005-09-30 2007-04-12 Oklahoma Medical Research Foundation Regulation of tool-like receptors on stem cells
SI2173381T1 (sl) 2007-05-14 2014-01-31 Novimmune Sa Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami
CN101589491B (zh) 2007-07-24 2011-07-27 松下电器产业株式会社 镍氢电池用负极材料及其处理方法以及镍氢电池
WO2009138494A2 (en) 2008-05-15 2009-11-19 Ablynx N.V. Amino acid sequences directed against toll-like receptors and polypeptides comprising the same for the treatment of diseases related to toll-like receptors
CN102239180B (zh) * 2008-08-18 2014-12-31 辉瑞大药厂 抗ccr2抗体
JP6289098B2 (ja) * 2011-01-10 2018-03-07 ノビミューン エスアー 抗ｔｌｒ４抗体およびその使用法

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