JP2014505056A5 - - Google Patents

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Publication number
JP2014505056A5
JP2014505056A5 JP2013548613A JP2013548613A JP2014505056A5 JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5 JP 2013548613 A JP2013548613 A JP 2013548613A JP 2013548613 A JP2013548613 A JP 2013548613A JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5
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JP
Japan
Prior art keywords
antibody
tlr4
immunologically active
active fragment
amino acid
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Application number
JP2013548613A
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English (en)
Japanese (ja)
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JP2014505056A (ja
JP6289098B2 (ja
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Priority claimed from PCT/US2012/020717 external-priority patent/WO2012096917A1/en
Publication of JP2014505056A publication Critical patent/JP2014505056A/ja
Publication of JP2014505056A5 publication Critical patent/JP2014505056A5/ja
Application granted granted Critical
Publication of JP6289098B2 publication Critical patent/JP6289098B2/ja
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JP2013548613A 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法 Active JP6289098B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161431191P 2011-01-10 2011-01-10
US61/431,191 2011-01-10
PCT/US2012/020717 WO2012096917A1 (en) 2011-01-10 2012-01-10 Anti-tlr4 antibodies and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017027473A Division JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法

Publications (3)

Publication Number Publication Date
JP2014505056A JP2014505056A (ja) 2014-02-27
JP2014505056A5 true JP2014505056A5 (enExample) 2015-02-26
JP6289098B2 JP6289098B2 (ja) 2018-03-07

Family

ID=46455425

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013548613A Active JP6289098B2 (ja) 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Country Status (7)

Country Link
US (4) US8734790B2 (enExample)
EP (2) EP2663330B1 (enExample)
JP (3) JP6289098B2 (enExample)
AU (2) AU2012205763B2 (enExample)
CA (1) CA2824060C (enExample)
ES (1) ES2721378T3 (enExample)
WO (1) WO2012096917A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2173381B1 (en) * 2007-05-14 2013-10-02 NovImmune SA Fc receptor-binding polypeptides with modified effector functions
WO2012096917A1 (en) * 2011-01-10 2012-07-19 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
CA2869048C (en) * 2012-03-29 2023-10-17 Novimmune S.A. Anti-tlr4 antibodies and uses thereof
CN105899231A (zh) * 2013-10-22 2016-08-24 诺夫免疫股份有限公司 用于在具有升高水平的tlr4配体和其它生物标记的患者中诊断和治疗病症的方法和组合物
CA2932787A1 (en) * 2013-12-06 2015-06-11 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
WO2017021552A1 (en) * 2015-08-06 2017-02-09 Novimmune Sa Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders
WO2017160599A1 (en) 2016-03-14 2017-09-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of cd300b antagonists to treat sepsis and septic shock
CN109481666B (zh) * 2018-12-21 2020-11-03 江苏省中医院 一种人体血液肿瘤pdx模型的建立方法
CN115697410A (zh) * 2020-04-20 2023-02-03 艾德沙生物科技研究公司 用于治疗急性呼吸窘迫综合征的组合物和方法
WO2022112198A1 (en) 2020-11-24 2022-06-02 Worldwide Innovative Network Method to select the optimal immune checkpoint therapies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5151510A (en) 1990-04-20 1992-09-29 Applied Biosystems, Inc. Method of synethesizing sulfurized oligonucleotide analogs
US5624946A (en) * 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
CN104178491B (zh) * 2002-09-06 2018-07-03 安姆根有限公司 治疗性人抗-il-1r1单克隆抗体
US7312320B2 (en) 2003-12-10 2007-12-25 Novimmune Sa Neutralizing antibodies and methods of use thereof
DK1711531T3 (da) 2003-12-10 2012-04-30 Novimmune Sa Neutraliserende anti-TLR4/-MD-2-antistoffer og fremgangsmåder til anvendelse deraf
US7674884B2 (en) 2003-12-10 2010-03-09 Novimmune S.A. Neutralizing antibodies and methods of use thereof
AU2005205533B2 (en) * 2004-01-07 2012-03-22 Novartis Vaccines And Diagnostics, Inc. M-CSF-specific monoclonal antibody and uses thereof
US7592003B2 (en) 2005-09-30 2009-09-22 Oklahoma Medical Research Foundation Regulation of toll-like receptors on stem cells
EP2173381B1 (en) * 2007-05-14 2013-10-02 NovImmune SA Fc receptor-binding polypeptides with modified effector functions
US8202650B2 (en) 2007-07-24 2012-06-19 Panasonic Corporation Negative electrode material for nickel-metal hydride battery and treatment method thereof, and nickel-metal hydride battery
WO2009138494A2 (en) 2008-05-15 2009-11-19 Ablynx N.V. Amino acid sequences directed against toll-like receptors and polypeptides comprising the same for the treatment of diseases related to toll-like receptors
KR101772706B1 (ko) * 2008-08-18 2017-08-29 화이자 인크. Ｃｃｒ２에 대한 항체
WO2012096917A1 (en) * 2011-01-10 2012-07-19 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof

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