JP2014505012A5 - - Google Patents
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- Publication number
- JP2014505012A5 JP2014505012A5 JP2013535058A JP2013535058A JP2014505012A5 JP 2014505012 A5 JP2014505012 A5 JP 2014505012A5 JP 2013535058 A JP2013535058 A JP 2013535058A JP 2013535058 A JP2013535058 A JP 2013535058A JP 2014505012 A5 JP2014505012 A5 JP 2014505012A5
- Authority
- JP
- Japan
- Prior art keywords
- monoclonal antibody
- amino acid
- acid sequence
- seq
- cell culture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39481210P | 2010-10-20 | 2010-10-20 | |
| US61/394,812 | 2010-10-20 | ||
| PCT/US2011/056966 WO2012054654A2 (en) | 2010-10-20 | 2011-10-19 | Anti-folate receptor alpha antibody glycoforms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014505012A JP2014505012A (ja) | 2014-02-27 |
| JP2014505012A5 true JP2014505012A5 (https=) | 2014-12-04 |
Family
ID=45975873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535058A Pending JP2014505012A (ja) | 2010-10-20 | 2011-10-19 | 抗葉酸受容体アルファ抗体の糖型 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20120164137A1 (https=) |
| EP (1) | EP2629798A4 (https=) |
| JP (1) | JP2014505012A (https=) |
| KR (1) | KR20140032944A (https=) |
| CN (1) | CN103347537A (https=) |
| AU (2) | AU2011317088B2 (https=) |
| BR (1) | BR112013009275A2 (https=) |
| CA (1) | CA2815080A1 (https=) |
| IL (1) | IL225579A0 (https=) |
| MX (1) | MX2013004202A (https=) |
| RU (1) | RU2013122843A (https=) |
| WO (1) | WO2012054654A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2607444C (en) * | 2005-04-22 | 2015-03-10 | Morphotek, Inc. | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells |
| BR112014028306A2 (pt) | 2012-05-15 | 2018-04-17 | Morphotek, Inc. | métodos para tratamento de câncer gástrico. |
| US9200073B2 (en) * | 2012-08-31 | 2015-12-01 | Immunogen, Inc. | Diagnostic assays and kits for detection of folate receptor 1 |
| US9207238B2 (en) | 2012-12-07 | 2015-12-08 | Kyowa Hakko Kirin Co., Ltd. | Anti-FOLR1 antibody |
| US8956830B2 (en) | 2013-03-14 | 2015-02-17 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| US9217168B2 (en) | 2013-03-14 | 2015-12-22 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| US20140271622A1 (en) * | 2013-03-14 | 2014-09-18 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| US9677105B2 (en) | 2013-03-14 | 2017-06-13 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| TWI832345B (zh) | 2013-03-14 | 2024-02-11 | 美商安美基公司 | 用於增加重組蛋白質之甘露糖含量之方法 |
| CN113150145B (zh) | 2013-08-30 | 2025-02-14 | 伊缪诺金公司 | 用于检测叶酸受体1的抗体和测定 |
| EP2871190A1 (en) * | 2013-11-11 | 2015-05-13 | ATLAB Pharma | Antibody against GD2-O-acetylated ganglioside with pro-apoptotic activity |
| PT3221356T (pt) | 2014-11-20 | 2020-10-29 | Hoffmann La Roche | Moléculas de ligação ao antigénio biespecíficas ativadoras das células t contra folr1 e cd3 |
| EP4141032B1 (en) | 2014-11-20 | 2024-05-29 | F. Hoffmann-La Roche AG | Combination therapy of t cell activating bispecific antigen binding molecules and pd-1 axis binding antagonists |
| DK3221357T3 (da) | 2014-11-20 | 2020-08-10 | Hoffmann La Roche | Fælles letkæder og fremgangsmåder til anvendelse |
| CA2969225C (en) | 2014-12-01 | 2023-08-22 | Amgen Inc. | Process for manipulating the level of glycan content of a glycoprotein |
| CN116440279B (zh) * | 2015-09-17 | 2026-02-24 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| AU2019236091B2 (en) | 2018-03-13 | 2025-06-05 | Phanes Therapeutics, Inc. | Anti-folate receptor 1 antibodies and uses thereof |
| KR102275930B1 (ko) * | 2018-03-14 | 2021-07-12 | (주)알테오젠 | Folr1에 특이적으로 결합하는 항체 및 그의 용도 |
| CN118344485B (zh) * | 2024-06-18 | 2024-10-15 | 南京欧凯生物科技有限公司 | 抗叶酸及其结合蛋白复合物的单克隆抗体或其抗原结合片段、其制备方法及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1648511A1 (en) * | 2003-07-29 | 2006-04-26 | Morphotek, Inc. | Antibodies and methods for generating genetically altered antibodies with enhanced effector function |
| EP3101034A1 (en) * | 2004-02-12 | 2016-12-07 | Morphotek, Inc. | Monoclonal antibodies that specifically bind to folate receptor alpha |
| AU2005274905B2 (en) * | 2004-08-04 | 2010-12-23 | Mentrik Biotech, Llc | Variant Fc regions |
| CN101374545B (zh) * | 2005-04-15 | 2012-03-28 | 免疫基因公司 | 消除肿瘤中的异质或混合细胞群体 |
| CA2607444C (en) * | 2005-04-22 | 2015-03-10 | Morphotek, Inc. | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells |
| SG153825A1 (en) * | 2005-12-16 | 2009-07-29 | Ibc Pharmaceuticals Inc | Multivalent immunoglobulin-based bioactive assemblies |
| WO2011116387A1 (en) * | 2010-03-19 | 2011-09-22 | Tetragenetics, Inc. | Production of aglycosylated monoclonal antibodies in ciliates |
-
2011
- 2011-10-19 CN CN2011800503838A patent/CN103347537A/zh active Pending
- 2011-10-19 MX MX2013004202A patent/MX2013004202A/es unknown
- 2011-10-19 JP JP2013535058A patent/JP2014505012A/ja active Pending
- 2011-10-19 EP EP11835098.2A patent/EP2629798A4/en not_active Withdrawn
- 2011-10-19 WO PCT/US2011/056966 patent/WO2012054654A2/en not_active Ceased
- 2011-10-19 CA CA2815080A patent/CA2815080A1/en not_active Abandoned
- 2011-10-19 KR KR1020137012669A patent/KR20140032944A/ko not_active Withdrawn
- 2011-10-19 RU RU2013122843/10A patent/RU2013122843A/ru not_active Application Discontinuation
- 2011-10-19 AU AU2011317088A patent/AU2011317088B2/en not_active Ceased
- 2011-10-19 BR BR112013009275A patent/BR112013009275A2/pt not_active Application Discontinuation
- 2011-10-19 US US13/277,161 patent/US20120164137A1/en not_active Abandoned
-
2013
- 2013-04-04 IL IL225579A patent/IL225579A0/en unknown
-
2016
- 2016-04-04 AU AU2016202082A patent/AU2016202082A1/en not_active Abandoned
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