JP2014503548A5 - - Google Patents
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- Publication number
- JP2014503548A5 JP2014503548A5 JP2013546460A JP2013546460A JP2014503548A5 JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5 JP 2013546460 A JP2013546460 A JP 2013546460A JP 2013546460 A JP2013546460 A JP 2013546460A JP 2014503548 A5 JP2014503548 A5 JP 2014503548A5
- Authority
- JP
- Japan
- Prior art keywords
- water
- compound
- soluble non
- peptide polymer
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCN(CC)CCNC(c1c(C)[n]c(C(**)C(c2cc(F)ccc2N2)C2=O)c1C)=O Chemical compound CCN(CC)CCNC(c1c(C)[n]c(C(**)C(c2cc(F)ccc2N2)C2=O)c1C)=O 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061426919P | 2010-12-23 | 2010-12-23 | |
| US61/426,919 | 2010-12-23 | ||
| PCT/US2011/067259 WO2012088529A1 (en) | 2010-12-23 | 2011-12-23 | Polymer-sunitinib conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016136547A Division JP2016185978A (ja) | 2010-12-23 | 2016-07-11 | ポリマー−スニチニブコンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014503548A JP2014503548A (ja) | 2014-02-13 |
| JP2014503548A5 true JP2014503548A5 (https=) | 2014-12-25 |
| JP6002149B2 JP6002149B2 (ja) | 2016-10-05 |
Family
ID=45529206
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013546460A Active JP6002149B2 (ja) | 2010-12-23 | 2011-12-23 | ポリマー−スニチニブコンジュゲート |
| JP2016136547A Withdrawn JP2016185978A (ja) | 2010-12-23 | 2016-07-11 | ポリマー−スニチニブコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016136547A Withdrawn JP2016185978A (ja) | 2010-12-23 | 2016-07-11 | ポリマー−スニチニブコンジュゲート |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US9827326B2 (https=) |
| EP (1) | EP2654799B1 (https=) |
| JP (2) | JP6002149B2 (https=) |
| WO (1) | WO2012088529A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6009457B2 (ja) | 2010-12-23 | 2016-10-19 | ネクター セラピューティクス | ポリマー−デスエチルスニチニブコンジュゲート |
| US9827326B2 (en) | 2010-12-23 | 2017-11-28 | Nektar Therapeutics | Polymer-sunitinib conjugates |
| WO2012088506A1 (en) | 2010-12-23 | 2012-06-28 | Nektar Therapeutics | Polymer-semaxanib moiety conjugates |
| EP3228650B1 (en) * | 2014-12-04 | 2022-03-09 | Delta-Fly Pharma, Inc. | Novel peg derivative |
| CN104610231B (zh) * | 2015-01-28 | 2016-08-17 | 广州葳澜生物科技有限公司 | 一种舒尼替尼前药 |
| KR20180058758A (ko) | 2015-09-22 | 2018-06-01 | 그레이버그 비젼, 인크. | 안구 장애의 치료를 위한 화합물 및 조성물 |
| EP3600324A4 (en) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS |
| AU2018265415A1 (en) | 2017-05-10 | 2019-10-31 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
| JP7680361B2 (ja) * | 2019-03-08 | 2025-05-20 | アプライド マテリアルズ インコーポレイテッド | 処理チャンバ用の多孔性シャワーヘッド |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4992540A (en) | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4810646A (en) | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US5028703A (en) | 1988-03-11 | 1991-07-02 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US5032401A (en) | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| ATE331514T1 (de) | 1999-12-22 | 2006-07-15 | Sugen Inc | Indolinonderivate zur abänderung der c-kit tyrosinproteinkinase |
| JP3663382B2 (ja) * | 2000-02-15 | 2005-06-22 | スージェン・インコーポレーテッド | ピロール置換２−インドリノン蛋白質キナーゼ阻害剤 |
| MXPA02010759A (es) | 2000-05-02 | 2004-07-30 | Sugen Inc | Derivados del acido (2-oxindol-3-ilidenil) acetico y su uso como inhibidores de la proteina quinasa. |
| MY128450A (en) | 2000-05-24 | 2007-02-28 | Upjohn Co | 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives |
| TWI259081B (en) | 2001-10-26 | 2006-08-01 | Sugen Inc | Treatment of acute myeloid leukemia with indolinone compounds |
| EP1446438A2 (en) | 2001-11-07 | 2004-08-18 | Nektar Therapeutics Al, Corporation | Branched polymers and their conjugates |
| US7053144B1 (en) | 2002-06-13 | 2006-05-30 | Cmi Rubber Company, Inc. | High density rubber compounds |
| WO2004084949A2 (en) | 2003-03-20 | 2004-10-07 | Xencor | Generating protein pro-drugs using reversible ppg linkages |
| EP2644206B1 (en) | 2003-05-23 | 2019-04-03 | Nektar Therapeutics | PEG derivatives containing two PEG chains |
| CA2537336C (en) | 2003-09-17 | 2013-02-26 | Nektar Therapeutics Al, Corporation | Multi-arm polymer prodrugs |
| WO2005108463A2 (en) | 2004-05-03 | 2005-11-17 | Nektar Therapeutics Al, Corporation | Branched polyethylen glycol derivates comprising an acetal or ketal branching point |
| WO2005107815A2 (en) | 2004-05-03 | 2005-11-17 | Nektar Therapeutics Al, Corporation | Polymer derivatives comprising an imide branching point |
| US7740861B2 (en) | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| HUE025208T2 (en) | 2005-06-16 | 2016-03-29 | Nektar Therapeutics | Conjugates with degradable binding and polymer reagents useful in the preparation of such conjugates |
| US8309680B2 (en) | 2006-02-21 | 2012-11-13 | Nektar Therapeutics | Segmented degradable polymers and conjugates made therefrom |
| US20080044438A1 (en) | 2006-03-17 | 2008-02-21 | Ostroff Gary R | Yeast Cell Particles As Oral Delivery Vehicles For Antigens |
| EP2114458B1 (en) | 2006-12-27 | 2014-02-26 | Nektar Therapeutics | Von willebrand factor- and factor viii-polymer conjugates having a releasable linkage |
| AU2008331868B2 (en) | 2007-11-28 | 2015-02-12 | Nektar Therapeutics | Oligomer-tricyclic conjugates |
| EP2254601B1 (en) | 2008-02-08 | 2019-05-29 | Nektar Therapeutics | Oligomer-cannabinoid conjugates |
| WO2009126333A1 (en) | 2008-04-11 | 2009-10-15 | Nektar Therapeutics | Oligomer-aryloxy-substituted propanamine conjugates |
| EP2303288A4 (en) * | 2008-05-22 | 2015-04-22 | Univ Ramot | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESE MEDIUM AND ITS USE IN THE TREATMENT AND CONTROL OF ILLNESSES RELATED TO BONE |
| AU2009282413B2 (en) | 2008-08-11 | 2014-07-17 | Nektar Therapeutics | Multi-arm polymeric alkanoate conjugates |
| WO2010091187A2 (en) | 2009-02-04 | 2010-08-12 | The Brigham And Women's Hospital, Inc. | Polymeric nanoparticles with enhanced drug-loading and methods of use thereof |
| WO2010120388A1 (en) * | 2009-04-17 | 2010-10-21 | Nektar Therapeutics | Oligomer-protein tyrosine kinase inhibitor conjugates |
| WO2010120387A1 (en) | 2009-04-17 | 2010-10-21 | Nektar Therapeutics | Oligomer-protein tyrosine kinase inhibitor conjugates |
| JP6009457B2 (ja) | 2010-12-23 | 2016-10-19 | ネクター セラピューティクス | ポリマー−デスエチルスニチニブコンジュゲート |
| US9827326B2 (en) | 2010-12-23 | 2017-11-28 | Nektar Therapeutics | Polymer-sunitinib conjugates |
-
2011
- 2011-12-23 US US13/996,834 patent/US9827326B2/en active Active
- 2011-12-23 JP JP2013546460A patent/JP6002149B2/ja active Active
- 2011-12-23 EP EP11811620.1A patent/EP2654799B1/en active Active
- 2011-12-23 WO PCT/US2011/067259 patent/WO2012088529A1/en not_active Ceased
-
2016
- 2016-07-11 JP JP2016136547A patent/JP2016185978A/ja not_active Withdrawn
-
2017
- 2017-10-24 US US15/792,060 patent/US10682418B2/en active Active
-
2020
- 2020-05-07 US US16/869,458 patent/US11419943B2/en active Active
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