JP2014503080A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014503080A5 JP2014503080A5 JP2013550604A JP2013550604A JP2014503080A5 JP 2014503080 A5 JP2014503080 A5 JP 2014503080A5 JP 2013550604 A JP2013550604 A JP 2013550604A JP 2013550604 A JP2013550604 A JP 2013550604A JP 2014503080 A5 JP2014503080 A5 JP 2014503080A5
- Authority
- JP
- Japan
- Prior art keywords
- glucose
- layer
- analyte sensing
- glucose oxidase
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010410 layer Substances 0.000 description 15
- MHAJPDPJQMAIIY-UHFFFAOYSA-N hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 10
- 239000012491 analyte Substances 0.000 description 9
- 108010015776 EC 1.1.3.4 Proteins 0.000 description 8
- 229940116332 GLUCOSE OXIDASE Drugs 0.000 description 8
- 239000004366 Glucose oxidase Substances 0.000 description 8
- 235000019420 glucose oxidase Nutrition 0.000 description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
- 239000008103 glucose Substances 0.000 description 5
- 239000002356 single layer Substances 0.000 description 2
- 108020005203 Oxidases Proteins 0.000 description 1
- 230000003750 conditioning Effects 0.000 description 1
- 230000001105 regulatory Effects 0.000 description 1
Description
本発明の別の実施形態は、層状グルコースセンサ装置内の過酸化水素分子の流れを調節する方法であり、この方法は、ベース層と、このベース層上に配置されかつ作用電極を含む導電層と、この導電層上に配置されかつ第1の濃度のグルコースオキシダーゼを含む第1の分析物感知層と、この第1の分析物感知層を覆うように配置されかつ第2の濃度のグルコースオキシダーゼを含む第2の分析物感知層と、この第2の分析物感知層を覆うように配置されかつ第3の濃度のグルコースオキシダーゼを含む第3の分析物感知層と、これら第1、第2、および第3の分析物感知層を覆うように配置された分析物調節層とを含むように、装置内で層を組織化するステップを含む。本発明のそのような実施形態では、第1、第2、および第3の分析物感知層内の第1、第2、および第3の濃度のグルコースオキシダーゼは、グルコースの存在下でグルコースオキシダーゼにより生成される第1、第2、および第3の層における過酸化水素分子の流れる角度を変化させて(例えば、単一の層または濃度のグルコースオキシダーゼと比較して)、層状グルコースセンサ装置内の過酸化水素分子の流れが調節されるように機能する。特定の科学理論または原理に拘泥するものではないが、そのような実施形態では、第1、第2、および第3の分析物感知層の種々のレベルのグルコースオキシダーゼは、グルコースの存在下でグルコースオキシダーゼにより生成される過酸化水素分子の流れる角度を変化させて、層状グルコースセンサ内の過酸化水素分子の流れが作用電極上の電気活性表面に最適に向かうように(例えば、単一の層または濃度のグルコースオキシダーゼと比較、例えば図8Cを参照)なされると考えられる。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/010,640 | 2011-01-20 | ||
US13/010,640 US8608921B2 (en) | 2011-01-20 | 2011-01-20 | Layered enzyme compositions for use with analyte sensors |
PCT/US2012/021980 WO2012100130A1 (en) | 2011-01-20 | 2012-01-20 | Layered enzyme compositions for use with analyte sensors |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2014503080A JP2014503080A (ja) | 2014-02-06 |
JP2014503080A5 true JP2014503080A5 (ja) | 2016-06-09 |
JP5950941B2 JP5950941B2 (ja) | 2016-07-13 |
Family
ID=45563566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013550604A Active JP5950941B2 (ja) | 2011-01-20 | 2012-01-20 | 分析物センサと共に使用される層状酵素組成物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US8608921B2 (ja) |
EP (1) | EP2665827B1 (ja) |
JP (1) | JP5950941B2 (ja) |
CN (1) | CN103328650B (ja) |
CA (1) | CA2822909C (ja) |
WO (1) | WO2012100130A1 (ja) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8346335B2 (en) | 2008-03-28 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte sensor calibration management |
US7653425B2 (en) | 2006-08-09 | 2010-01-26 | Abbott Diabetes Care Inc. | Method and system for providing calibration of an analyte sensor in an analyte monitoring system |
US8219173B2 (en) | 2008-09-30 | 2012-07-10 | Abbott Diabetes Care Inc. | Optimizing analyte sensor calibration |
US7618369B2 (en) | 2006-10-02 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for dynamically updating calibration parameters for an analyte sensor |
US20080199894A1 (en) | 2007-02-15 | 2008-08-21 | Abbott Diabetes Care, Inc. | Device and method for automatic data acquisition and/or detection |
US8239166B2 (en) | 2007-05-14 | 2012-08-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US9125548B2 (en) | 2007-05-14 | 2015-09-08 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8103471B2 (en) | 2007-05-14 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8600681B2 (en) | 2007-05-14 | 2013-12-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
DK3988470T3 (da) | 2009-08-31 | 2023-08-28 | Abbott Diabetes Care Inc | Visningsindretninger til en medicinsk indretning |
WO2011041469A1 (en) | 2009-09-29 | 2011-04-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing notification function in analyte monitoring systems |
EP2617076B1 (en) * | 2010-09-15 | 2014-12-10 | Ricoh Company, Limited | Electromechanical transducing device and manufacturing method thereof |
US8808532B2 (en) * | 2011-01-20 | 2014-08-19 | Medtronic Minimed, Inc | Electrode compositions for use with analyte sensors |
EP2518497A1 (de) * | 2011-04-29 | 2012-10-31 | Roche Diagnostics GmbH | Elektrochemisches Sensorelement für Körperflüssigkeiten und Herstellungsverfahren dafür |
US8710993B2 (en) | 2011-11-23 | 2014-04-29 | Abbott Diabetes Care Inc. | Mitigating single point failure of devices in an analyte monitoring system and methods thereof |
US20140012115A1 (en) * | 2012-07-03 | 2014-01-09 | Medtronic Minimed, Inc. | Plasma deposited adhesion promoter layers for use with analyte sensors |
WO2014035732A1 (en) | 2012-08-30 | 2014-03-06 | Abbot Diabetes Care Inc. | Dropout detection in continuous analyte monitoring data during data excursions |
US9907492B2 (en) | 2012-09-26 | 2018-03-06 | Abbott Diabetes Care Inc. | Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data |
US9750445B2 (en) * | 2013-06-28 | 2017-09-05 | Verily Life Sciences Llc | Porous polymeric formulation prepared using porogens |
US9551680B2 (en) | 2013-06-28 | 2017-01-24 | Verily Life Sciences Llc | Chemically reactive enzyme immobilization |
US9828620B2 (en) | 2013-06-28 | 2017-11-28 | Verily Life Sciences Llc | Porous polymeric formulation prepared using monomer |
US9763605B2 (en) | 2013-11-27 | 2017-09-19 | Verily Life Sciences Llc | Adjustment of sensor sensitivity by controlling copolymer film thickness through a controlled drying step |
US9617578B2 (en) * | 2013-12-06 | 2017-04-11 | Verily Life Sciences Llc | Sensor membrane with low temperature coefficient |
US9834805B2 (en) | 2013-12-23 | 2017-12-05 | Verily Life Sciences Llc | Two-layer analyte sensor |
US10321858B2 (en) | 2014-08-18 | 2019-06-18 | Proteadx, Inc. | Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems |
US10575767B2 (en) * | 2015-05-29 | 2020-03-03 | Medtronic Minimed, Inc. | Method for monitoring an analyte, analyte sensor and analyte monitoring apparatus |
CN113786195A (zh) * | 2015-09-02 | 2021-12-14 | 梅特罗诺姆中国Ip控股公司 | 使用光-酶分析物传感器进行连续健康监测的系统和方法 |
WO2017066268A1 (en) * | 2015-10-12 | 2017-04-20 | Ohio University | Supercapacitor-based biosensors and methods of detecting a biomarker |
JP6741934B2 (ja) * | 2015-10-19 | 2020-08-19 | 富士通株式会社 | 二酸化炭素還元用電極、及び二酸化炭素還元装置 |
SI3423591T1 (sl) * | 2016-03-04 | 2024-03-29 | Abbott Diabetes Care Inc., | Od NAD(P) odvisni odzivni encimi, elektrode in senzorji ter postopki za izdelavo in uporabo le-teh |
US11298059B2 (en) | 2016-05-13 | 2022-04-12 | PercuSense, Inc. | Analyte sensor |
EP3540423A4 (en) * | 2016-11-08 | 2020-07-22 | JSR Corporation | ENZYME SENSOR AND ENZYME SENSOR SYSTEM |
US11596330B2 (en) | 2017-03-21 | 2023-03-07 | Abbott Diabetes Care Inc. | Methods, devices and system for providing diabetic condition diagnosis and therapy |
US11512384B2 (en) * | 2017-05-11 | 2022-11-29 | Medtronic Minimed, Inc. | Analyte sensors and methods for fabricating analyte sensors |
WO2019017030A1 (ja) * | 2017-07-19 | 2019-01-24 | ソニー株式会社 | センサデバイス、検出装置 |
CN112088217A (zh) * | 2018-05-16 | 2020-12-15 | 美敦力泌力美公司 | 用于葡萄糖传感器的热稳定葡萄糖限制膜 |
CN113260307A (zh) * | 2018-06-29 | 2021-08-13 | 普罗菲尤萨股份有限公司 | 层状传感器及其使用方法 |
US11823808B2 (en) | 2018-09-19 | 2023-11-21 | University Of Massachusetts | Conductive composite materials fabricated with protein nanowires |
AU2020214230B2 (en) | 2019-01-28 | 2023-03-02 | Abbott Diabetes Care Inc. | Analyte sensors employing multiple enzymes and methods associated therewith |
CN110051365A (zh) * | 2019-04-23 | 2019-07-26 | 重庆大学 | 一种用于长期持续监测的植入式电极 |
US11631824B2 (en) * | 2020-04-08 | 2023-04-18 | University Of Massachusetts | Memristor device comprising protein nanowires |
US11982637B2 (en) | 2020-04-22 | 2024-05-14 | University Of Massachusetts | Sensors comprising electrically-conductive protein nanowires |
US20220338768A1 (en) * | 2021-04-09 | 2022-10-27 | Medtronic Minimed, Inc. | Hexamethyldisiloxane membranes for analyte sensors |
US20240158827A1 (en) * | 2022-10-28 | 2024-05-16 | Medtronic Minimed, Inc. | Enzyme mediator functionalized polymers for use with analyte sensors |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57106853A (en) * | 1980-12-24 | 1982-07-02 | Toshiba Corp | Enzyme electrode |
US4418148A (en) * | 1981-11-05 | 1983-11-29 | Miles Laboratories, Inc. | Multilayer enzyme electrode membrane |
US5312590A (en) | 1989-04-24 | 1994-05-17 | National University Of Singapore | Amperometric sensor for single and multicomponent analysis |
JPH09257742A (ja) * | 1996-03-19 | 1997-10-03 | Toa Denpa Kogyo Kk | アルコールセンサ |
JP4721618B2 (ja) * | 2000-09-25 | 2011-07-13 | 旭化成株式会社 | 酵素電極 |
US20070227907A1 (en) * | 2006-04-04 | 2007-10-04 | Rajiv Shah | Methods and materials for controlling the electrochemistry of analyte sensors |
US20050272989A1 (en) | 2004-06-04 | 2005-12-08 | Medtronic Minimed, Inc. | Analyte sensors and methods for making and using them |
JP2004156989A (ja) * | 2002-11-06 | 2004-06-03 | Matsushita Electric Ind Co Ltd | バイオセンサ |
US7415299B2 (en) * | 2003-04-18 | 2008-08-19 | The Regents Of The University Of California | Monitoring method and/or apparatus |
CA2545715C (en) | 2003-11-13 | 2012-10-16 | Medtronic Minimed, Inc. | Long term analyte sensor array |
US20100025238A1 (en) * | 2008-07-31 | 2010-02-04 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
US8660628B2 (en) * | 2009-12-21 | 2014-02-25 | Medtronic Minimed, Inc. | Analyte sensors comprising blended membrane compositions and methods for making and using them |
-
2011
- 2011-01-20 US US13/010,640 patent/US8608921B2/en active Active
-
2012
- 2012-01-20 JP JP2013550604A patent/JP5950941B2/ja active Active
- 2012-01-20 CN CN201280005930.5A patent/CN103328650B/zh active Active
- 2012-01-20 WO PCT/US2012/021980 patent/WO2012100130A1/en active Application Filing
- 2012-01-20 CA CA2822909A patent/CA2822909C/en active Active
- 2012-01-20 EP EP12702686.2A patent/EP2665827B1/en active Active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2014503080A5 (ja) | ||
EP4344632A3 (en) | Zwitterion surface modifications for continuous sensors | |
JP2012247372A5 (ja) | ||
IN2014DN06797A (ja) | ||
EA201590725A1 (ru) | Устройство и способы применения пропитанных жидкостью поверхностей | |
EP2728404A3 (en) | Liquid crystal lens device and method of driving the same | |
GB2510752A (en) | Nanogap transducers with selective surface immobilization sites | |
BRPI0922050A2 (pt) | proteção de processamento multi-espacial e controle de volume dinâmico | |
JP2015532461A5 (ja) | ||
EP2463628A3 (en) | Portable navigation device and method with active elements | |
JP2011505522A5 (ja) | ||
FR2981438B1 (fr) | Capteur solaire rigide ou souple avec une image visualisee en surface, et ses procedes de fabrication | |
BRPI0913333A2 (pt) | avatar de usuário compartilhado entre aplicações e dispositivos de computação | |
TR201910307T4 (tr) | Kontrol cihazı. | |
WO2011099831A3 (ko) | 그래핀을 이용한 유연성 투명 발열체 및 이의 제조 방법 | |
WO2009104840A3 (en) | Hybrid electric device using piezo-electric polymer substrate and its fabrication method | |
JP2014235133A5 (ja) | ||
JP2016535988A5 (ja) | ||
EP2560171A3 (en) | Nonvolatile resistive memory elements and memory devices including the same | |
JP2011519271A5 (ja) | ||
WO2012017306A3 (en) | Electrochemical sensor | |
EP2857349A3 (en) | Gas sensor package | |
JP2012227137A5 (ja) | 発光装置 | |
JP2014146772A5 (ja) | ||
JP2013140343A5 (ja) |