JP2014502730A - 標的適用の磁場を利用する統合高周波発生器システム - Google Patents
標的適用の磁場を利用する統合高周波発生器システム Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
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- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
- G01R33/3607—RF waveform generators, e.g. frequency generators, amplitude-, frequency- or phase modulators or shifters, pulse programmers, digital to analog converters for the RF signal, means for filtering or attenuating of the RF signal
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- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J25/00—Transit-time tubes, e.g. klystrons, travelling-wave tubes, magnetrons
- H01J25/02—Tubes with electron stream modulated in velocity or density in a modulator zone and thereafter giving up energy in an inducing zone, the zones being associated with one or more resonators
- H01J25/025—Tubes with electron stream modulated in velocity or density in a modulator zone and thereafter giving up energy in an inducing zone, the zones being associated with one or more resonators with an electron stream following a helical path
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- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/381—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets
- G01R33/3815—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
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- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/387—Compensation of inhomogeneities
- G01R33/3873—Compensation of inhomogeneities using ferromagnetic bodies ; Passive shimming
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- G—PHYSICS
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- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/387—Compensation of inhomogeneities
- G01R33/3875—Compensation of inhomogeneities using correction coil assemblies, e.g. active shimming
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
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Abstract
Description
本出願は、この参照により本明細書に組み込まれる、35U.S.C.§§119、120、363、365、ならびに37C.F.R.§1.55および§1.78の下で2011年1月11日に出願された米国特許出願第12/930,584号の優先権を主張するものである。
10’ 従来技術のマイクロ波発生器
10a ジャイロトロン、高周波発生器、テラヘルツ源、線源
10a’ 本発明によるマイクロ波発生器
12 電子銃
14 電子ビーム
14a 電子ビーム
16 磁気システム、磁気システムコイル、補助磁場源
16a コア中の磁気システム
16b コイル中の磁気システム
16c アンペアターン巻線
18 相互作用構造体、空洞
18’ 内部モード変換器、相互作用構造体
18a’ 内部モード変換器
20 内部モード変換器
21 導波管ランチャー
21a ランチャー
21a’ ランチャー
22 マイクロ波反射体、ミラー
22’ 放物面集束ミラー
22’’ ミラー
22a ミラー
24 マイクロ波反射体、ミラー
24’ マイクロ波ミラー
24’’ ミラー
24’’’ ミラー
24a 放物面ミラー
24a’’ ミラー
26 窓
26’ 窓
26a 窓
26a’ 窓
26a’’ 窓
28 電子ビームの広がり
30 コレクター
30a コレクター
30aa コレクター
40 従来の磁気共鳴システム
42 磁石、磁石装置、主磁石コイル
44 適用ゾーン
46 磁気共鳴試料
48 プローブ、磁石プローブ装置
50 マイクロ波導波管
52 極低温システムおよび制御装置
54 コンソール
56 線源制御ラック
58 電子銃トリムコイル
60 磁気コイル、主巻線
62 強磁性または空気のコア
64 穴
66 磁力線
68 磁力線
70 シムコイル
72 シムコイル
76 マイクロ波発生器ゾーン
78 フリンジエリア
80 マイクロ波導波管
90 軸方向磁場の空間プロファイル、磁気共鳴磁場
92 上昇領域
94 均一領域
96 減衰領域
98 軸方向磁場プロファイル
100 上昇部分
102 均一部分
104 減衰部分
106 垂直線
108 垂直線、マイクロ波発生器ゾーン
110 合成磁場
112 隆起した部分
120 軸方向磁場プロファイル
122 均一領域
124 上昇領域
125 垂直線
126 減衰部分
127 垂直線
Claims (29)
- 磁気共鳴磁石の磁場中に適用ゾーンおよび高周波(マイクロ波/テラヘルツ)発生器ゾーンを有する前記磁気共鳴磁石と、
前記高周波(マイクロ波/テラヘルツ)発生器ゾーンに配置され、前記磁気共鳴磁石の磁場を利用して高周波(マイクロ波/テラヘルツ)放射を発生させる高周波(マイクロ波/テラヘルツ)発生器とを含む、標的適用の磁場を利用する統合高周波発生器システム。 - 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記磁気共鳴磁石の主磁場中にある、請求項1に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記磁気共鳴磁石のフリンジ磁場中にある、請求項1に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンでの磁場プロファイルを変更するための補助磁場源をさらに含む、請求項1に記載の統合システム。
- 前記補助磁場源は、前記高周波(マイクロ波/テラヘルツ)発生器上に取り付けられた巻線を含む、請求項4に記載の統合システム。
- 前記補助磁場源は、前記磁気共鳴磁石中に取り付けられた巻線を含む、請求項4に記載の統合システム。
- 前記補助磁場源は、少なくとも1つの永久磁石から成る、請求項4に記載の統合システム。
- 前記補助磁場源は、前記磁気共鳴磁石での変更点を含む、請求項4に記載の統合システム。
- 前記磁気共鳴磁石は、少なくとも1つの巻線を含み、前記変更点は、前記磁気共鳴磁石の巻線のアンペアターンの変化を含む、請求項8に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)発生器から前記適用ゾーンまで延びている高周波(マイクロ波/テラヘルツ)伝送線路をさらに含む、請求項3に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)放射は、DNPを行うために使用される、請求項4に記載の統合システム。
- 前記補助磁場源は、前記適用ゾーンでDNPプロセスを可能にするために前記高周波(マイクロ波/テラヘルツ)発生器からの高周波(マイクロ波/テラヘルツ)放射を同期させるように前記高周波(マイクロ波/テラヘルツ)発生器ゾーンでの前記磁場プロファイルの値を変更する、請求項4に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)発生器は、電子ビームの集束、輸送および前記電子ビームとVEDの回路との間の相互作用の少なくとも1つのために磁気共鳴システムの磁場を利用する、請求項1に記載の統合システム。
- 前記高周波(マイクロ波/テラヘルツ)共鳴磁石は、穴を含み、前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記穴にある、請求項1に記載の統合システム。
- 磁気共鳴磁石の磁場中に適用ゾーンおよび高周波(マイクロ波/テラヘルツ)発生器ゾーンを有する前記磁気共鳴磁石と、前記高周波(マイクロ波/テラヘルツ)発生器ゾーンでの磁場プロファイルを変更するための補助磁場源とを含む磁気共鳴磁石装置。
- 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記磁気共鳴磁石の主磁場中にある、請求項15に記載の磁気共鳴磁石装置。
- 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記磁気共鳴磁石のフリンジ磁場中にある、請求項15に記載の磁気共鳴磁石装置。
- 前記高周波(マイクロ波/テラヘルツ)発生器ゾーンでの磁場プロファイルを変更するための補助磁場源をさらに含む、請求項15に記載の磁気共鳴磁石装置。
- 前記補助磁場源は、前記磁気共鳴磁石中に取り付けられた巻線を含む、請求項18に記載の磁気共鳴磁石装置。
- 前記補助磁場源は、前記磁気共鳴磁石での変更点を含む、請求項18に記載の磁気共鳴磁石装置。
- 前記磁気共鳴磁石は、少なくとも1つの巻線を含み、前記変更点は、前記磁気共鳴磁石の巻線のアンペアターンの変化を含む、請求項20に記載の磁気共鳴磁石装置。
- 前記マイクロ波発生器から前記適用ゾーンまで延びているマイクロ波伝送線路をさらに含む、請求項17に記載の磁気共鳴磁石装置。
- 高周波(マイクロ波/テラヘルツ)放射は、DNPを行うために使用される、請求項18に記載の磁気共鳴磁石装置。
- 前記補助磁場源は、前記適用ゾーンでDNPプロセスを可能にするために前記マイクロ波発生器からの高周波(マイクロ波/テラヘルツ)放射を同期させるように前記高周波(マイクロ波/テラヘルツ)発生器ゾーンでの前記磁場プロファイルの大きさを増加させる、請求項18に記載の磁気共鳴磁石装置。
- 前記マイクロ波発生器は、電子ビームの集束、輸送または前記電子ビームとVEDの回路との間の相互作用の少なくとも1つのために磁気共鳴システムの磁場を利用する、請求項15に記載の磁気共鳴磁石装置。
- 前記磁気共鳴磁石は、穴を含み、前記高周波(マイクロ波/テラヘルツ)発生器ゾーンは、前記穴にある、請求項15に記載の磁気共鳴磁石装置。
- 空間的上昇領域、均一領域および減衰領域を有する磁場源によって集束されるように適合された電子ビームを発生させるための電子銃と、
高周波(マイクロ波/テラヘルツ)放射を発生させるための相互作用構造体と、
窓を通じて前記高周波(マイクロ波/テラヘルツ)放射を引き出すための前記均一領域での内部モード変換器と、
前記電子ビームが前記減衰領域で広がる前の前記均一領域に実質的に配置された縮小コレクターとを含む高周波(マイクロ波/テラヘルツ)発生器。 - 前記相互作用構造体および内部モード変換器に近接して磁場源をさらに含む、請求項27に記載の高周波(マイクロ波/テラヘルツ)発生器。
- 前記内部モード変換器は、前記ビームに一般に平行で、前記ビームを直接前記窓の外に向ける高周波(マイクロ波/テラヘルツ)反射体を含む、請求項27に記載の高周波(マイクロ波/テラヘルツ)発生器。
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US12/930,584 US8786284B2 (en) | 2011-01-11 | 2011-01-11 | Integrated high-frequency generator system utilizing the magnetic field of the target application |
US12/930,584 | 2011-01-11 | ||
PCT/US2011/002011 WO2012096644A1 (en) | 2011-01-11 | 2011-12-29 | Integrated high-frequency generator system utilizing the magnetic field of the target application |
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WO2019039477A1 (ja) * | 2017-08-23 | 2019-02-28 | 国立大学法人大阪大学 | 原子核スピンの高偏極化方法及び高偏極化装置 |
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