JP2014500268A5 - - Google Patents
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- Publication number
- JP2014500268A5 JP2014500268A5 JP2013542563A JP2013542563A JP2014500268A5 JP 2014500268 A5 JP2014500268 A5 JP 2014500268A5 JP 2013542563 A JP2013542563 A JP 2013542563A JP 2013542563 A JP2013542563 A JP 2013542563A JP 2014500268 A5 JP2014500268 A5 JP 2014500268A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- following formula
- formula
- btm
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 8
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 5
- 230000002285 radioactive effect Effects 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 3
- 239000002872 contrast media Substances 0.000 claims 3
- 238000003384 imaging method Methods 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 125000002344 aminooxy group Chemical group [H]N([H])O[*] 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N hydrazine group Chemical group NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 claims 1
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000000732 arylene group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000002993 cycloalkylene group Chemical group 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000002532 enzyme inhibitor Substances 0.000 claims 1
- 229940125532 enzyme inhibitor Drugs 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 150000002337 glycosamines Chemical class 0.000 claims 1
- 125000005549 heteroarylene group Chemical group 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 238000000163 radioactive labelling Methods 0.000 claims 1
- 239000012217 radiopharmaceutical Substances 0.000 claims 1
- 229940121896 radiopharmaceutical Drugs 0.000 claims 1
- 230000002799 radiopharmaceutical effect Effects 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42139010P | 2010-12-09 | 2010-12-09 | |
| US61/421,390 | 2010-12-09 | ||
| PCT/EP2011/072352 WO2012076697A1 (en) | 2010-12-09 | 2011-12-09 | Radiotracer compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014500268A JP2014500268A (ja) | 2014-01-09 |
| JP2014500268A5 true JP2014500268A5 (enExample) | 2015-01-29 |
| JP6055417B2 JP6055417B2 (ja) | 2016-12-27 |
Family
ID=45346469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542563A Active JP6055417B2 (ja) | 2010-12-09 | 2011-12-09 | 放射性トレーサー組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9180213B2 (enExample) |
| EP (1) | EP2648767B1 (enExample) |
| JP (1) | JP6055417B2 (enExample) |
| KR (1) | KR20130124522A (enExample) |
| CN (2) | CN103338791A (enExample) |
| CA (1) | CA2820387A1 (enExample) |
| WO (1) | WO2012076697A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201202420D0 (en) * | 2012-02-13 | 2012-03-28 | Ge Healthcare Ltd | Radiotracer compositions |
| CN104470547B (zh) * | 2012-05-24 | 2018-01-26 | 未来化学株式会社 | 利用筒状物合成放射性药物的方法 |
| GB201221266D0 (en) * | 2012-11-27 | 2013-01-09 | Ge Healthcare Ltd | Aldehyde compositions |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| WO2016087653A1 (en) * | 2014-12-04 | 2016-06-09 | Ge Healthcare Limited | Method of removing acetaldehyde from radioactive pharmaceuticals |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0305704D0 (en) | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
| US7659400B2 (en) | 2003-07-31 | 2010-02-09 | Washington University | Radiolabelled benzamide analogues, their synthesis and use in diagnostic imaging |
| GB0420344D0 (en) | 2004-09-14 | 2004-10-13 | Amersham Plc | Diagnostic compounds |
| AU2006285278B2 (en) * | 2005-08-31 | 2011-05-12 | Immunomedics, Inc. | F-18 peptides for pre targeted positron emission tomography imaging |
| EP2109466B1 (en) | 2007-02-07 | 2014-11-12 | Purdue Research Foundation | Positron emission tomography imaging method |
| US20080318577A1 (en) | 2007-06-25 | 2008-12-25 | Interdigital Technology Corporation | Method and apparatus for supporting inter-frequency and inter-radio access technology handover |
| US8124725B2 (en) * | 2007-12-19 | 2012-02-28 | General Electric Company | PDGF-Rβ binders |
| WO2010000409A2 (en) * | 2008-07-03 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Compounds and processes for production of radiopharmaceuticals |
| GB0905438D0 (en) * | 2009-03-30 | 2009-05-13 | Ge Healthcare Ltd | Radiolabelling reagents and methods |
| EP2322500A1 (en) | 2009-11-11 | 2011-05-18 | Bayer Schering Pharma Aktiengesellschaft | Fluoro-labeled homo-glutamate derivatives and precursors thereof |
| US20130149243A1 (en) | 2009-11-17 | 2013-06-13 | Bayer Intellectual Property Gmbh | Method for production of f-18 labeled glutamic acid derivatives |
-
2011
- 2011-12-09 JP JP2013542563A patent/JP6055417B2/ja active Active
- 2011-12-09 CN CN2011800590925A patent/CN103338791A/zh active Pending
- 2011-12-09 CA CA2820387A patent/CA2820387A1/en not_active Abandoned
- 2011-12-09 EP EP11794725.9A patent/EP2648767B1/en active Active
- 2011-12-09 CN CN201711237827.4A patent/CN107753962A/zh active Pending
- 2011-12-09 US US13/992,800 patent/US9180213B2/en active Active
- 2011-12-09 WO PCT/EP2011/072352 patent/WO2012076697A1/en not_active Ceased
- 2011-12-09 KR KR1020137017594A patent/KR20130124522A/ko not_active Withdrawn
-
2015
- 2015-10-07 US US14/877,107 patent/US9987382B2/en active Active
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