KR20130124522A - 방사성 추적자 조성물 - Google Patents

방사성 추적자 조성물 Download PDF

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Publication number
KR20130124522A
KR20130124522A KR1020137017594A KR20137017594A KR20130124522A KR 20130124522 A KR20130124522 A KR 20130124522A KR 1020137017594 A KR1020137017594 A KR 1020137017594A KR 20137017594 A KR20137017594 A KR 20137017594A KR 20130124522 A KR20130124522 A KR 20130124522A
Authority
KR
South Korea
Prior art keywords
composition
formula
btm
group
imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020137017594A
Other languages
English (en)
Korean (ko)
Inventor
토르그림 엔겔
줄리안 그리그
디미트리오스 만칠라스
Original Assignee
지이 헬쓰케어 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지이 헬쓰케어 리미티드 filed Critical 지이 헬쓰케어 리미티드
Publication of KR20130124522A publication Critical patent/KR20130124522A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020137017594A 2010-12-09 2011-12-09 방사성 추적자 조성물 Withdrawn KR20130124522A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42139010P 2010-12-09 2010-12-09
US61/421,390 2010-12-09
PCT/EP2011/072352 WO2012076697A1 (en) 2010-12-09 2011-12-09 Radiotracer compositions

Publications (1)

Publication Number Publication Date
KR20130124522A true KR20130124522A (ko) 2013-11-14

Family

ID=45346469

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137017594A Withdrawn KR20130124522A (ko) 2010-12-09 2011-12-09 방사성 추적자 조성물

Country Status (7)

Country Link
US (2) US9180213B2 (enExample)
EP (1) EP2648767B1 (enExample)
JP (1) JP6055417B2 (enExample)
KR (1) KR20130124522A (enExample)
CN (2) CN103338791A (enExample)
CA (1) CA2820387A1 (enExample)
WO (1) WO2012076697A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170093132A (ko) * 2014-12-04 2017-08-14 지이 헬쓰케어 리미티드 방사성 약제로부터의 아세트알데히드의 제거 방법

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201202420D0 (en) * 2012-02-13 2012-03-28 Ge Healthcare Ltd Radiotracer compositions
CN104470547B (zh) * 2012-05-24 2018-01-26 未来化学株式会社 利用筒状物合成放射性药物的方法
GB201221266D0 (en) * 2012-11-27 2013-01-09 Ge Healthcare Ltd Aldehyde compositions
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0305704D0 (en) 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
US7659400B2 (en) 2003-07-31 2010-02-09 Washington University Radiolabelled benzamide analogues, their synthesis and use in diagnostic imaging
GB0420344D0 (en) * 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
WO2007027385A2 (en) * 2005-08-31 2007-03-08 Immunomedics, Inc. F-18 peptides for pre targeted positron emission tomography imaging
JP5869205B2 (ja) * 2007-02-07 2016-02-24 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ ポジトロン放射断層画像法
US20080318577A1 (en) 2007-06-25 2008-12-25 Interdigital Technology Corporation Method and apparatus for supporting inter-frequency and inter-radio access technology handover
US8124725B2 (en) * 2007-12-19 2012-02-28 General Electric Company PDGF-Rβ binders
EP2297070A2 (en) * 2008-07-03 2011-03-23 Bayer Schering Pharma Aktiengesellschaft Compounds and processes for production of radiopharmaceuticals
GB0905438D0 (en) 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
EP2322500A1 (en) 2009-11-11 2011-05-18 Bayer Schering Pharma Aktiengesellschaft Fluoro-labeled homo-glutamate derivatives and precursors thereof
EP2501663A2 (en) 2009-11-17 2012-09-26 Piramal Imaging SA Method for production of f-18 labeled glutamic acid derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170093132A (ko) * 2014-12-04 2017-08-14 지이 헬쓰케어 리미티드 방사성 약제로부터의 아세트알데히드의 제거 방법
US11389538B2 (en) 2014-12-04 2022-07-19 Ge Healthcare Limited Method for removing acetaldehyde
KR20220148308A (ko) * 2014-12-04 2022-11-04 지이 헬쓰케어 리미티드 방사성 약제로부터의 아세트알데히드의 제거 방법
US11964020B2 (en) 2014-12-04 2024-04-23 Ge Healthcare Limited Method for removing acetaldehyde

Also Published As

Publication number Publication date
US20160022847A1 (en) 2016-01-28
JP6055417B2 (ja) 2016-12-27
JP2014500268A (ja) 2014-01-09
CA2820387A1 (en) 2012-06-14
CN103338791A (zh) 2013-10-02
CN107753962A (zh) 2018-03-06
EP2648767B1 (en) 2023-03-15
EP2648767A1 (en) 2013-10-16
US20130259804A1 (en) 2013-10-03
WO2012076697A1 (en) 2012-06-14
US9180213B2 (en) 2015-11-10
US9987382B2 (en) 2018-06-05

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20130705

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid