JP2014028839A5 - - Google Patents
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- Publication number
- JP2014028839A5 JP2014028839A5 JP2013198117A JP2013198117A JP2014028839A5 JP 2014028839 A5 JP2014028839 A5 JP 2014028839A5 JP 2013198117 A JP2013198117 A JP 2013198117A JP 2013198117 A JP2013198117 A JP 2013198117A JP 2014028839 A5 JP2014028839 A5 JP 2014028839A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- fungal
- bacterial
- colonization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims description 28
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims description 28
- 206010035664 Pneumonia Diseases 0.000 claims description 21
- 230000002538 fungal effect Effects 0.000 claims description 20
- 208000036142 Viral infection Diseases 0.000 claims description 18
- 230000001580 bacterial effect Effects 0.000 claims description 18
- 230000009385 viral infection Effects 0.000 claims description 18
- 206010017533 Fungal infection Diseases 0.000 claims description 17
- 208000031888 Mycoses Diseases 0.000 claims description 17
- 206010006448 Bronchiolitis Diseases 0.000 claims description 15
- 208000023367 bronchiolitis obliterans with obstructive pulmonary disease Diseases 0.000 claims description 9
- 230000000414 obstructive effect Effects 0.000 claims description 9
- 201000003883 Cystic fibrosis Diseases 0.000 claims description 8
- 208000019693 Lung disease Diseases 0.000 claims description 6
- 241000124008 Mammalia Species 0.000 claims description 6
- 201000009267 bronchiectasis Diseases 0.000 claims description 6
- 208000024891 symptom Diseases 0.000 claims description 6
- 208000008745 Healthcare-Associated Pneumonia Diseases 0.000 claims description 5
- 206010006451 bronchitis Diseases 0.000 claims description 5
- 201000000317 pneumocystosis Diseases 0.000 claims description 5
- 230000002685 pulmonary effect Effects 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 4
- 210000004072 lung Anatomy 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 230000000241 respiratory effect Effects 0.000 claims description 4
- 239000000725 suspension Substances 0.000 claims description 4
- 239000000443 aerosol Substances 0.000 claims description 3
- 238000013276 bronchoscopy Methods 0.000 claims description 3
- 239000002502 liposome Substances 0.000 claims description 3
- 239000002105 nanoparticle Substances 0.000 claims description 3
- 206010067472 Organising pneumonia Diseases 0.000 claims description 2
- 201000009805 cryptogenic organizing pneumonia Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 20
- 241001673062 Achromobacter xylosoxidans Species 0.000 claims 1
- 241001508003 Mycobacterium abscessus Species 0.000 claims 1
- 208000005384 Pneumocystis Pneumonia Diseases 0.000 claims 1
- 206010073755 Pneumocystis jirovecii pneumonia Diseases 0.000 claims 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 26
- 208000035143 Bacterial infection Diseases 0.000 description 9
- 208000022362 bacterial infectious disease Diseases 0.000 description 9
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 6
- 201000005202 lung cancer Diseases 0.000 description 6
- 208000020816 lung neoplasm Diseases 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 4
- 241000233870 Pneumocystis Species 0.000 description 4
- 206010062952 diffuse panbronchiolitis Diseases 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 230000003612 virological effect Effects 0.000 description 3
- 230000007123 defense Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 206010061876 Obstruction Diseases 0.000 description 1
- 206010041067 Small cell lung cancer Diseases 0.000 description 1
- 208000009470 Ventilator-Associated Pneumonia Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 210000003123 bronchiole Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 208000000587 small cell lung carcinoma Diseases 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86419006P | 2006-11-03 | 2006-11-03 | |
| US60/864,190 | 2006-11-03 | ||
| US94751107P | 2007-07-02 | 2007-07-02 | |
| US60/947,511 | 2007-07-02 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Division JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015204558A Division JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014028839A JP2014028839A (ja) | 2014-02-13 |
| JP2014028839A5 true JP2014028839A5 (cg-RX-API-DMAC7.html) | 2014-05-15 |
Family
ID=39344625
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Pending JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
| JP2013198117A Pending JP2014028839A (ja) | 2006-11-03 | 2013-09-25 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
| JP2015204558A Active JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535569A Pending JP2010508365A (ja) | 2006-11-03 | 2007-11-02 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015204558A Active JP6001151B2 (ja) | 2006-11-03 | 2015-10-16 | 顆粒球マクロファージコロニー刺激因子を投与することによる肺の宿主防御の増強 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100015217A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2094290B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2010508365A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007315402B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0717958B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2668292C (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009004802A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008052567A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008116470A1 (en) * | 2007-03-26 | 2008-10-02 | Drugrecure Aps | Enhancing pulmonary host defence via administration of granulocyte- colony stimulating factor |
| US9161969B2 (en) | 2011-03-22 | 2015-10-20 | Board Of Regents, The University Of Texas System | Protection against influenza infection by granulocyte-macrophage colony stimulating factor |
| WO2012136224A2 (en) * | 2011-04-07 | 2012-10-11 | Trifoilium Aps | Methods and compositions for enhancing pulmonary host defense in acute and chronic radiation syndrome, therapeutic radiation intervention and cancer therapy |
| WO2013029627A1 (en) * | 2011-08-29 | 2013-03-07 | Trifoilium Aps | Compositions and methods for treating or preventing radiation- or chemotherapy-induced pulmonary dysfunction |
| US9370189B2 (en) | 2012-05-18 | 2016-06-21 | Syracuse University | Controlling Pseudomonas aeruginosa persister cells with GM-CSF |
| EP2877199A1 (en) * | 2012-07-20 | 2015-06-03 | Trifoilium ApS | Granulocyte-macrophage colony-stimulating factor for the treatment of bronchial asthma |
| WO2014096032A1 (en) * | 2012-12-18 | 2014-06-26 | Trifoilium Aps | Gm-csf for treatment of chronic sinusitis |
| WO2014128173A1 (en) | 2013-02-20 | 2014-08-28 | Trifoilium Aps | Gm-csf for treatment of chronic oral mucositis |
| WO2015110536A1 (en) * | 2014-01-22 | 2015-07-30 | Reponex Pharmaceuticals Aps | Granulocyte-macrophage colony-stimulating factor for the treatment and prevention of severe forms of bronchial asthma |
| EP3662924A1 (en) | 2014-03-07 | 2020-06-10 | Reponex Pharmaceuticals A/S | Compositions for treating lung infections by airway administration |
| EP3145533B8 (en) * | 2014-05-23 | 2024-05-01 | Reponex Pharmaceuticals A/S | Compositions for promoting the healing of wounds |
| US10105415B2 (en) | 2014-07-24 | 2018-10-23 | Reponex Pharmaceuticals A/S | Compositions comprising granulocyte-macrophage colony-stimulating factor for the treatment of inflammatory bowel disease |
| JP7545893B2 (ja) * | 2017-10-16 | 2024-09-05 | ドラッグレキュア エーピーエス | 難治性非結核性マイコバクテリア感染症の治療のためのｇｍ－ｃｓｆ |
| WO2021188883A1 (en) * | 2020-03-20 | 2021-09-23 | The Regents Of The University Of Colorado, A Body Corporate | Methods and compositions for the treatment of viral disease using granulocyte-macrophage colony-stimulating factor (gm-csf) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) * | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5391485A (en) * | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US5162111A (en) * | 1986-07-30 | 1992-11-10 | Grabstein Kenneth H | Treatment of bacterial diseases with granulocyte-macrophage colony stimulating factor |
| US4837028A (en) * | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US9269067B2 (en) * | 2002-04-04 | 2016-02-23 | Altisource Solutions S.À.R.L. | Method and apparatus for providing selective access to information |
| US7512585B2 (en) | 2002-07-11 | 2009-03-31 | Oracle International Corporation | Support for multiple mechanisms for accessing data stores |
-
2007
- 2007-11-02 US US12/513,215 patent/US20100015217A1/en not_active Abandoned
- 2007-11-02 EP EP07817959.5A patent/EP2094290B1/en active Active
- 2007-11-02 BR BRPI0717958A patent/BRPI0717958B8/pt active IP Right Grant
- 2007-11-02 WO PCT/DK2007/050161 patent/WO2008052567A2/en not_active Ceased
- 2007-11-02 AU AU2007315402A patent/AU2007315402B2/en active Active
- 2007-11-02 JP JP2009535569A patent/JP2010508365A/ja active Pending
- 2007-11-02 CA CA2668292A patent/CA2668292C/en active Active
- 2007-11-02 MX MX2009004802A patent/MX2009004802A/es active IP Right Grant
-
2013
- 2013-09-25 JP JP2013198117A patent/JP2014028839A/ja active Pending
-
2015
- 2015-10-16 JP JP2015204558A patent/JP6001151B2/ja active Active
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