JP2014028787A5 - - Google Patents
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- Publication number
- JP2014028787A5 JP2014028787A5 JP2012199657A JP2012199657A JP2014028787A5 JP 2014028787 A5 JP2014028787 A5 JP 2014028787A5 JP 2012199657 A JP2012199657 A JP 2012199657A JP 2012199657 A JP2012199657 A JP 2012199657A JP 2014028787 A5 JP2014028787 A5 JP 2014028787A5
- Authority
- JP
- Japan
- Prior art keywords
- keratinocytes
- whitening agent
- integrin
- whitening
- action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002510 keratinocyte Anatomy 0.000 claims 19
- 230000002087 whitening effect Effects 0.000 claims 18
- 239000003795 chemical substances by application Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 14
- 230000002401 inhibitory effect Effects 0.000 claims 13
- 238000012216 screening Methods 0.000 claims 8
- 230000021164 cell adhesion Effects 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
- 238000012360 testing method Methods 0.000 claims 5
- 102000000426 Integrin alpha6 Human genes 0.000 claims 4
- 108010041100 Integrin alpha6 Proteins 0.000 claims 4
- 102000012334 Integrin beta4 Human genes 0.000 claims 4
- 108010022238 Integrin beta4 Proteins 0.000 claims 4
- 230000014509 gene expression Effects 0.000 claims 4
- 102000006495 integrins Human genes 0.000 claims 4
- 108010044426 integrins Proteins 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000013461 design Methods 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 210000002469 basement membrane Anatomy 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 108010028309 kalinin Proteins 0.000 claims 1
- 210000004379 membrane Anatomy 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000012549 training Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012199657A JP6113981B2 (ja) | 2012-06-29 | 2012-09-11 | スクリ−ニング方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012146197 | 2012-06-29 | ||
| JP2012146197 | 2012-06-29 | ||
| JP2012199657A JP6113981B2 (ja) | 2012-06-29 | 2012-09-11 | スクリ−ニング方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014028787A JP2014028787A (ja) | 2014-02-13 |
| JP2014028787A5 true JP2014028787A5 (enExample) | 2015-06-25 |
| JP6113981B2 JP6113981B2 (ja) | 2017-04-12 |
Family
ID=50201648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012199657A Active JP6113981B2 (ja) | 2012-06-29 | 2012-09-11 | スクリ−ニング方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6113981B2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6763497B1 (ja) * | 2020-03-25 | 2020-09-30 | 大正製薬株式会社 | ミネラル代謝異常抑制剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005013885A2 (en) * | 2003-08-07 | 2005-02-17 | Healor Ltd. | Pharmaceutical compositions and methods for accelerating wound healing |
| JP5014569B2 (ja) * | 2004-09-16 | 2012-08-29 | オリザ油化株式会社 | 美肌用組成物 |
| JP2008127357A (ja) * | 2006-11-22 | 2008-06-05 | Konan Kako Kk | 皮膚外用剤組成物 |
| JP5787285B2 (ja) * | 2010-09-06 | 2015-09-30 | 公立大学法人大阪市立大学 | 線維芽細胞増殖促進剤、角化細胞遊走・増殖促進剤、エラスチン産生促進剤、ヒートショックタンパク質４７産生促進剤、α−平滑筋アクチン（α−ＳＭＡ）産生促進剤、及び光老化防止剤。 |
-
2012
- 2012-09-11 JP JP2012199657A patent/JP6113981B2/ja active Active
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