JP2013544285A5 - - Google Patents
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- Publication number
- JP2013544285A5 JP2013544285A5 JP2013542100A JP2013542100A JP2013544285A5 JP 2013544285 A5 JP2013544285 A5 JP 2013544285A5 JP 2013542100 A JP2013542100 A JP 2013542100A JP 2013542100 A JP2013542100 A JP 2013542100A JP 2013544285 A5 JP2013544285 A5 JP 2013544285A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxylamine
- triazin
- propylamino
- bis
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41777710P | 2010-11-29 | 2010-11-29 | |
| US61/417,777 | 2010-11-29 | ||
| US201161494268P | 2011-06-07 | 2011-06-07 | |
| US61/494,268 | 2011-06-07 | ||
| PCT/US2011/062386 WO2012074999A1 (en) | 2010-11-29 | 2011-11-29 | Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544285A JP2013544285A (ja) | 2013-12-12 |
| JP2013544285A5 true JP2013544285A5 (enExample) | 2015-03-12 |
| JP5907986B2 JP5907986B2 (ja) | 2016-04-26 |
Family
ID=46162783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542100A Active JP5907986B2 (ja) | 2010-11-29 | 2011-11-29 | 呼吸制御障害または呼吸制御疾患の処置用の呼吸刺激薬としての化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9351972B2 (enExample) |
| EP (1) | EP2646423A4 (enExample) |
| JP (1) | JP5907986B2 (enExample) |
| KR (1) | KR20140049961A (enExample) |
| CN (1) | CN103347866B (enExample) |
| AU (1) | AU2011336764B2 (enExample) |
| BR (1) | BR112013013429A2 (enExample) |
| CA (1) | CA2819333A1 (enExample) |
| SG (2) | SG190921A1 (enExample) |
| WO (1) | WO2012074999A1 (enExample) |
| ZA (1) | ZA201303960B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2755394C (en) | 2009-03-13 | 2021-10-19 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
| BRPI1011587B1 (pt) | 2009-06-29 | 2020-03-24 | Agios Pharmaceuticals, Inc. | Compostos de quinolina sulfonamida com atividade moduladora de pmk2 e uso dos mesmos |
| EP3064595B1 (en) | 2009-10-21 | 2019-02-27 | Agios Pharmaceuticals, Inc. | Methods for cell-proliferation-related disorders |
| TR201809699T4 (tr) | 2011-05-03 | 2018-07-23 | Agios Pharmaceuticals Inc | Tedavi̇de kullanilmaya yöneli̇k pi̇ruvat ki̇naz akti̇vatörleri̇. |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| MD20140023A2 (ro) | 2011-09-22 | 2014-06-30 | Pfizer Inc. | Derivaţi de pirolpirimidină şi purină |
| AU2013207289B2 (en) | 2012-01-06 | 2017-09-21 | Les Laboratoires Servier | Therapeutically active compounds and their methods of use |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| CA2875012A1 (en) * | 2012-05-29 | 2013-12-05 | Galleon Pharmaceuticals, Inc. | Novel compounds and compositions for treatment of breathing control disorders or diseases |
| WO2014062511A1 (en) | 2012-10-15 | 2014-04-24 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| KR20150082633A (ko) * | 2012-11-15 | 2015-07-15 | 갈레온 파마슈티칼스, 인코포레이티드 | 경구적으로 생체이용가능한 신규 호흡 조절 제어 화합물 및 그의 사용 방법 |
| CA2905950A1 (en) | 2013-03-15 | 2014-09-25 | Galleon Pharmaceuticals, Inc. | Novel breathing control modulating compounds, and methods of using same |
| WO2015003360A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| KR102302091B1 (ko) | 2013-07-11 | 2021-09-16 | 아지오스 파마슈티컬스 아이엔씨. | 암 치료용의 ｉｄｈ２ 돌연변이체 억제제로서의 ｎ,６-비스(아릴 또는 헤테로아릴)-１，３，５-트리아진-２,４-디아민 화합물 |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| CA2917671A1 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | 2,4-or 4,6-diaminopyrimidine compounds as idh2 mutants inhibitors for the treatment of cancer |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| KR102400737B1 (ko) | 2014-03-14 | 2022-05-20 | 아지오스 파마슈티컬스 아이엔씨. | 치료적으로 활성인 화합물의 약제학적 조성물 |
| HRP20231247T1 (hr) | 2015-06-11 | 2024-02-02 | Agios Pharmaceuticals, Inc. | Postupci uporabe aktivatora piruvat kinaze |
| NO346258B1 (en) * | 2015-06-30 | 2022-05-16 | Neurad Ltd | Novel breathing control modulating compounds, and methods of making and using same |
| SG10202111439SA (en) | 2015-10-15 | 2021-11-29 | Les Laboratoires Servier Sas | Combination therapy for treating malignancies |
| EP3362066B1 (en) | 2015-10-15 | 2021-10-06 | Les Laboratoires Servier SAS | Combination therapy for treating malignancies |
| JP2020536045A (ja) | 2017-01-17 | 2020-12-10 | デイヴィッド フォレスト マイケル | Ａｔｐ合成酵素のリバースモードの治療的阻害剤 |
| JP2021510365A (ja) | 2017-07-13 | 2021-04-22 | デイヴィッド フォレスト マイケル | Ａｔｐシンターゼの逆モードの治療的モジュレーター |
| WO2019063390A1 (en) * | 2017-09-28 | 2019-04-04 | Koninklijke Philips N.V. | SYSTEM AND METHOD FOR DETECTION OF CEREBRAL VASCULAR ACCIDENTS IN PATIENTS DURING PRESSURE SUPPORT THERAPY |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| CN114173872A (zh) * | 2019-05-22 | 2022-03-11 | 依那拉治疗股份有限公司 | 治疗药物过量的方法和药物组合物 |
| AU2022270648A1 (en) * | 2021-05-04 | 2023-12-07 | Enalare Therapeutics Inc. | Large-conductance potassium channel modulators, compositions thereof, methods of manufacturing thereof, and methods of use thereof |
| CA3236586A1 (en) | 2021-11-02 | 2023-05-11 | Joseph Pergolizzi | Methods of treating respiratory depression modulated by a non-opioid agent |
| EP4456900A4 (en) * | 2021-12-27 | 2025-12-24 | Enalare Therapeutics Inc | RESPIRATORY STIMULATING PARENTERAL FORMULATIONS |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037980A (en) | 1955-08-18 | 1962-06-05 | Burroughs Wellcome Co | Pyrrolopyrimidine vasodilators and method of making them |
| GB1001665A (en) | 1961-06-05 | 1965-08-18 | American Cyanamid Co | Triazine derivatives and process for their preparation |
| ES2087916T3 (es) | 1989-10-11 | 1996-08-01 | Teijin Ltd | Derivado de pirimidina biciclico, metodo para producir el mismo, y preparacion farmaceutica que contiene el mismo como ingrediente activo. |
| JPH08272059A (ja) | 1995-03-31 | 1996-10-18 | Fuji Photo Film Co Ltd | 多層ハロゲン化銀カラー写真感光材料包装体 |
| JPH09189973A (ja) | 1996-01-08 | 1997-07-22 | Fuji Photo Film Co Ltd | ハロゲン化銀乳剤及びこれを用いる写真感光材料 |
| JPH09251197A (ja) | 1996-03-15 | 1997-09-22 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
| JPH09304898A (ja) | 1996-05-15 | 1997-11-28 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
| ATE377003T1 (de) * | 1999-01-22 | 2007-11-15 | Elan Pharm Inc | Verbindungen die die vla-4 vermittelte adhäsion von leukozyten inhibieren |
| US6525067B1 (en) | 1999-11-23 | 2003-02-25 | Pfizer Inc | Substituted heterocyclic derivatives |
| US20020065270A1 (en) * | 1999-12-28 | 2002-05-30 | Moriarty Kevin Joseph | N-heterocyclic inhibitors of TNF-alpha expression |
| CA2394727A1 (en) | 1999-12-28 | 2001-07-05 | Pharmacopeia, Inc. | Pyrimidine and triazine kinase inhibitors |
| CA2451125A1 (en) * | 2001-06-26 | 2003-01-09 | Bristol-Myers Squibb Company | N-heterocyclic inhibitors of tnf-alpha expression |
| MXPA04002680A (es) * | 2001-09-21 | 2004-06-18 | Reddy Therapeutics Inc | Metodos y composiciones de compuestos de triazina novedosos. |
| US20030168629A1 (en) * | 2001-12-10 | 2003-09-11 | Lazar Warren G. | Reactive liquid polymer crosslinking agent and process for preparation |
| CA2476934C (en) | 2002-02-27 | 2009-06-16 | Immunex Corporation | Stabilized tnfr-fc composition comprising arginine |
| US20040063658A1 (en) | 2002-05-06 | 2004-04-01 | Roberts Christopher Don | Nucleoside derivatives for treating hepatitis C virus infection |
| WO2004028481A2 (en) | 2002-09-30 | 2004-04-08 | Genelabs Technologies, Inc. | Nucleoside derivatives for treating hepatitis c virus infection |
| WO2004043367A2 (en) | 2002-11-06 | 2004-05-27 | Bristol-Myers Squibb Company | Fused heterocyclic compounds and use thereof |
| AU2004259346A1 (en) * | 2003-07-22 | 2005-02-03 | Neurogen Corporation | Substituted pyridin-2-ylamine analogues |
| CA2556946A1 (en) | 2004-03-05 | 2005-09-15 | Taisho Pharmaceutical Co., Ltd. | Pyrrolopyrimidine derivatives |
| US20080021135A1 (en) | 2004-03-15 | 2008-01-24 | Honeywell International, Inc. | Cellulose Reinforced Resin Compositions |
| WO2006023703A2 (en) * | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders |
| WO2007079163A2 (en) * | 2005-12-29 | 2007-07-12 | Janssen Pharmaceutica N.V. | Prokineticin 1 receptor antagonists |
| CA2652040C (en) * | 2006-05-17 | 2015-07-21 | Albert Einstein College Of Medicine Of Yeshiva University | Prostaglandin transporter inhibitors |
| GB0610317D0 (en) | 2006-05-24 | 2006-07-05 | Medical Res Council | Antiparasitic compounds and compositions |
| EP1889847A1 (en) | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| EP2059512A1 (en) * | 2006-08-01 | 2009-05-20 | Praecis Pharmaceuticals Incorporated | P38 kinase inhibitors |
| US20080119457A1 (en) | 2006-08-24 | 2008-05-22 | Serenex, Inc. | Benzene, Pyridine, and Pyridazine Derivatives |
| WO2008105968A1 (en) * | 2006-11-03 | 2008-09-04 | Smithkline Beecham Corporation | Novel seh inhibitors and their use |
| WO2009115084A2 (de) | 2008-03-20 | 2009-09-24 | Schebo Biotech Ag | Neue pyrrolopyrimidin-derivate und deren verwendungen |
| CN101885707B (zh) | 2009-05-15 | 2012-08-29 | 中国科学院化学研究所 | 三嗪类衍生物及其制备方法与作为杀虫剂的用途 |
-
2011
- 2011-11-29 EP EP11845815.7A patent/EP2646423A4/en not_active Withdrawn
- 2011-11-29 SG SG2013041439A patent/SG190921A1/en unknown
- 2011-11-29 KR KR1020137016890A patent/KR20140049961A/ko not_active Ceased
- 2011-11-29 US US13/306,349 patent/US9351972B2/en active Active
- 2011-11-29 WO PCT/US2011/062386 patent/WO2012074999A1/en not_active Ceased
- 2011-11-29 JP JP2013542100A patent/JP5907986B2/ja active Active
- 2011-11-29 BR BR112013013429A patent/BR112013013429A2/pt not_active IP Right Cessation
- 2011-11-29 CA CA2819333A patent/CA2819333A1/en not_active Abandoned
- 2011-11-29 AU AU2011336764A patent/AU2011336764B2/en not_active Expired - Fee Related
- 2011-11-29 SG SG10201601507YA patent/SG10201601507YA/en unknown
- 2011-11-29 CN CN201180066258.6A patent/CN103347866B/zh not_active Expired - Fee Related
-
2013
- 2013-05-30 ZA ZA2013/03960A patent/ZA201303960B/en unknown
-
2016
- 2016-05-16 US US15/155,897 patent/US20160256463A1/en not_active Abandoned
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