JP2013544285A5 - - Google Patents
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- Publication number
- JP2013544285A5 JP2013544285A5 JP2013542100A JP2013542100A JP2013544285A5 JP 2013544285 A5 JP2013544285 A5 JP 2013544285A5 JP 2013542100 A JP2013542100 A JP 2013542100A JP 2013542100 A JP2013542100 A JP 2013542100A JP 2013544285 A5 JP2013544285 A5 JP 2013544285A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxylamine
- triazin
- propylamino
- bis
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41777710P | 2010-11-29 | 2010-11-29 | |
| US61/417,777 | 2010-11-29 | ||
| US201161494268P | 2011-06-07 | 2011-06-07 | |
| US61/494,268 | 2011-06-07 | ||
| PCT/US2011/062386 WO2012074999A1 (en) | 2010-11-29 | 2011-11-29 | Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544285A JP2013544285A (ja) | 2013-12-12 |
| JP2013544285A5 true JP2013544285A5 (cg-RX-API-DMAC7.html) | 2015-03-12 |
| JP5907986B2 JP5907986B2 (ja) | 2016-04-26 |
Family
ID=46162783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542100A Active JP5907986B2 (ja) | 2010-11-29 | 2011-11-29 | 呼吸制御障害または呼吸制御疾患の処置用の呼吸刺激薬としての化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9351972B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2646423A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5907986B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140049961A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103347866B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011336764B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013013429A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2819333A1 (cg-RX-API-DMAC7.html) |
| SG (2) | SG10201601507YA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012074999A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201303960B (cg-RX-API-DMAC7.html) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524505A (zh) | 2009-03-13 | 2018-09-14 | 安吉奥斯医药品有限公司 | 用于细胞增殖相关病症的方法和组合物 |
| PT2448582T (pt) | 2009-06-29 | 2017-07-10 | Agios Pharmaceuticals Inc | Compostos e composições terapêuticas |
| ES2594402T3 (es) | 2009-10-21 | 2016-12-20 | Agios Pharmaceuticals, Inc. | Métodos y composiciones para trastornos relacionados con la proliferación celular |
| SG194697A1 (en) | 2011-05-03 | 2013-12-30 | Agios Pharmaceuticals Inc | Pyruvate kinase activators for use in therapy |
| CN102827170A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| CN102827073A (zh) | 2011-06-17 | 2012-12-19 | 安吉奥斯医药品有限公司 | 治疗活性组合物和它们的使用方法 |
| ES2575710T3 (es) | 2011-09-22 | 2016-06-30 | Pfizer Inc | Derivados de pirrolopirimidina y purina |
| SI2800743T1 (en) | 2012-01-06 | 2018-08-31 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and methods for their use |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| HK1209118A1 (en) * | 2012-05-29 | 2016-03-24 | Galleon Pharmaceuticals, Inc. | Novel compounds and compositions for treatment of breathing control disorders or diseases |
| NZ706999A (en) | 2012-10-15 | 2018-12-21 | Agios Pharmaceuticals Inc | Inhibitors of mutant isocitrate dehydrogenase and therapeutical uses thereof |
| JP2015537032A (ja) * | 2012-11-15 | 2015-12-24 | ガリオン ファーマシューティカルズ インコーポレイテッド | 経口バイオアベイラビリティーを有する呼吸制御調節化合物およびそれを使用する方法 |
| WO2014151462A1 (en) * | 2013-03-15 | 2014-09-25 | Galleon Pharmaceuticals, Inc. | Novel breathing control modulating compounds, and methods of using same |
| US9579324B2 (en) | 2013-07-11 | 2017-02-28 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| WO2015003360A2 (en) * | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| NZ715738A (en) | 2013-07-11 | 2021-06-25 | Agios Pharmaceuticals Inc | N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer |
| WO2015003355A2 (en) | 2013-07-11 | 2015-01-15 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds and their methods of use |
| US10376510B2 (en) | 2013-07-11 | 2019-08-13 | Agios Pharmaceuticals, Inc. | 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer |
| US20150031627A1 (en) | 2013-07-25 | 2015-01-29 | Agios Pharmaceuticals, Inc | Therapeutically active compounds and their methods of use |
| CN112159391A (zh) | 2014-03-14 | 2021-01-01 | 阿吉奥斯制药公司 | 治疗活性化合物的药物组合物 |
| SI3307271T1 (sl) | 2015-06-11 | 2023-11-30 | Agios Pharmaceuticals, Inc. | Postopki za uporabo aktivatorjev piruvat kinaze |
| KR102207539B1 (ko) * | 2015-06-30 | 2021-01-26 | 네우라드 리미티드 | 신규한 호흡 제어 조절 화합물, 및 그의 제조 및 사용 방법 |
| HUE057263T2 (hu) | 2015-10-15 | 2022-04-28 | Servier Lab | Kombinációs terápia rosszindulató betegségek kezelésére |
| EP3362065B1 (en) | 2015-10-15 | 2024-04-03 | Les Laboratoires Servier | Combination therapy comprising ivosidenib, cytarabine and daunorubicin or idarubicin for treating acute myelogenous leukemia |
| JP2020536045A (ja) | 2017-01-17 | 2020-12-10 | デイヴィッド フォレスト マイケル | Ａｔｐ合成酵素のリバースモードの治療的阻害剤 |
| BR112019028172A2 (pt) | 2017-07-13 | 2020-10-06 | Michael David Forrest | moduladores terapêuticos do modo reverso da atp sintase |
| EP3688770A1 (en) * | 2017-09-28 | 2020-08-05 | Koninklijke Philips N.V. | System and method for detecting stroke in patients during pressure support therapy |
| US10980788B2 (en) | 2018-06-08 | 2021-04-20 | Agios Pharmaceuticals, Inc. | Therapy for treating malignancies |
| CA3141612A1 (en) * | 2019-05-22 | 2020-11-26 | Enalare Therapeutics Inc. | Methods and pharmaceutical compositions to treat drug overdose |
| KR20240004887A (ko) * | 2021-05-04 | 2024-01-11 | 에날레어 테라퓨틱스 인크. | 고전도도의 칼륨 채널 조정제, 이의 조성물, 이의 제조 방법, 및 이의 사용 방법 |
| US12138267B2 (en) | 2021-11-02 | 2024-11-12 | Enalare Therapeutics Inc. | Methods of treating respiratory depression modulated by a non-opioid agent |
| EP4456900A4 (en) * | 2021-12-27 | 2025-12-24 | Enalare Therapeutics Inc | RESPIRATORY STIMULATING PARENTERAL FORMULATIONS |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037980A (en) | 1955-08-18 | 1962-06-05 | Burroughs Wellcome Co | Pyrrolopyrimidine vasodilators and method of making them |
| GB1001665A (en) | 1961-06-05 | 1965-08-18 | American Cyanamid Co | Triazine derivatives and process for their preparation |
| DE69027440T2 (de) | 1989-10-11 | 1997-02-06 | Teijin Ltd | Bizyklische pyrimidinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung |
| JPH08272059A (ja) | 1995-03-31 | 1996-10-18 | Fuji Photo Film Co Ltd | 多層ハロゲン化銀カラー写真感光材料包装体 |
| JPH09189973A (ja) * | 1996-01-08 | 1997-07-22 | Fuji Photo Film Co Ltd | ハロゲン化銀乳剤及びこれを用いる写真感光材料 |
| JPH09251197A (ja) | 1996-03-15 | 1997-09-22 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
| JPH09304898A (ja) | 1996-05-15 | 1997-11-28 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
| IL143929A0 (en) * | 1999-01-22 | 2002-04-21 | Elan Pharm Inc | Acyl derivatives which treat vla-4 related disorders |
| US6525067B1 (en) * | 1999-11-23 | 2003-02-25 | Pfizer Inc | Substituted heterocyclic derivatives |
| AU2457201A (en) * | 1999-12-28 | 2001-07-09 | Bristol-Myers Squibb Company | Cytokine, especially tnf-alpha, inhibitors |
| US20020065270A1 (en) * | 1999-12-28 | 2002-05-30 | Moriarty Kevin Joseph | N-heterocyclic inhibitors of TNF-alpha expression |
| HUP0401712A3 (en) * | 2001-06-26 | 2009-06-29 | Bristol Myers Squibb Co | N-heterocyclic inhibitors of tnf-alpha and pharmaceutical compositions containing them |
| BR0212895A (pt) * | 2001-09-21 | 2005-05-10 | Reddy Us Therapeutics Inc | Métodos e composições de novos compostos de triazina |
| US20030168629A1 (en) * | 2001-12-10 | 2003-09-11 | Lazar Warren G. | Reactive liquid polymer crosslinking agent and process for preparation |
| PT1946776T (pt) | 2002-02-27 | 2017-03-17 | Immunex Corp | Composição de tnfr-fc estabilizada compreendendo arginina |
| MXPA04010983A (es) | 2002-05-06 | 2005-02-14 | Genelabs Tech Inc | Derivados de nucleosidos para tratar infecciones por el virus de la hepatitis c. |
| TW200418498A (en) | 2002-09-30 | 2004-10-01 | Genelabs Tech Inc | Nucleoside derivatives for treating hepatitis C virus infection |
| US7384937B2 (en) | 2002-11-06 | 2008-06-10 | Bristol-Myers Squibb Co. | Fused heterocyclic compounds and use thereof |
| CN1826328A (zh) * | 2003-07-22 | 2006-08-30 | 神经能质公司 | 经取代的吡啶－2－基胺类似物 |
| CN1926140A (zh) * | 2004-03-05 | 2007-03-07 | 大正制药株式会社 | 吡咯并嘧啶衍生物 |
| WO2005090469A1 (en) | 2004-03-15 | 2005-09-29 | Honeywell International Inc. | Cellulose reinforced resin compositions |
| WO2006023702A2 (en) | 2004-08-20 | 2006-03-02 | Cypress Bioscience, Inc. | Method for treating sleep related breathing disorders with setiptiline |
| CN101495464B (zh) * | 2005-12-29 | 2014-03-05 | 詹森药业有限公司 | 激肽原1受体拮抗剂 |
| US8227466B2 (en) * | 2006-05-17 | 2012-07-24 | Albert Einstein College Of Medicine Of Yeshiva University | Prostaglandin transporter inhibitors |
| GB0610317D0 (en) | 2006-05-24 | 2006-07-05 | Medical Res Council | Antiparasitic compounds and compositions |
| EP1889847A1 (en) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| EP2059512A1 (en) * | 2006-08-01 | 2009-05-20 | Praecis Pharmaceuticals Incorporated | P38 kinase inhibitors |
| WO2008024978A2 (en) | 2006-08-24 | 2008-02-28 | Serenex, Inc. | Tetrahydroindolone and tetrahydroindazolone derivatives |
| JP2010509233A (ja) * | 2006-11-03 | 2010-03-25 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 新規ｓＥＨ阻害剤およびそれらの使用 |
| WO2009115084A2 (de) | 2008-03-20 | 2009-09-24 | Schebo Biotech Ag | Neue pyrrolopyrimidin-derivate und deren verwendungen |
| CN101885707B (zh) * | 2009-05-15 | 2012-08-29 | 中国科学院化学研究所 | 三嗪类衍生物及其制备方法与作为杀虫剂的用途 |
-
2011
- 2011-11-29 SG SG10201601507YA patent/SG10201601507YA/en unknown
- 2011-11-29 SG SG2013041439A patent/SG190921A1/en unknown
- 2011-11-29 KR KR1020137016890A patent/KR20140049961A/ko not_active Ceased
- 2011-11-29 CA CA2819333A patent/CA2819333A1/en not_active Abandoned
- 2011-11-29 WO PCT/US2011/062386 patent/WO2012074999A1/en not_active Ceased
- 2011-11-29 JP JP2013542100A patent/JP5907986B2/ja active Active
- 2011-11-29 US US13/306,349 patent/US9351972B2/en active Active
- 2011-11-29 BR BR112013013429A patent/BR112013013429A2/pt not_active IP Right Cessation
- 2011-11-29 EP EP11845815.7A patent/EP2646423A4/en not_active Withdrawn
- 2011-11-29 CN CN201180066258.6A patent/CN103347866B/zh not_active Expired - Fee Related
- 2011-11-29 AU AU2011336764A patent/AU2011336764B2/en not_active Expired - Fee Related
-
2013
- 2013-05-30 ZA ZA2013/03960A patent/ZA201303960B/en unknown
-
2016
- 2016-05-16 US US15/155,897 patent/US20160256463A1/en not_active Abandoned
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