JP2013544254A5 - - Google Patents

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Publication number
JP2013544254A5
JP2013544254A5 JP2013539982A JP2013539982A JP2013544254A5 JP 2013544254 A5 JP2013544254 A5 JP 2013544254A5 JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013544254 A5 JP2013544254 A5 JP 2013544254A5
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JP
Japan
Prior art keywords
combination
receptor antagonist
chemotherapeutic agent
prolactin receptor
patient
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Application number
JP2013539982A
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English (en)
Japanese (ja)
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JP2013544254A (ja
JP6306886B2 (ja
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Priority claimed from US12/948,329 external-priority patent/US8648046B2/en
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Publication of JP2013544254A publication Critical patent/JP2013544254A/ja
Publication of JP2013544254A5 publication Critical patent/JP2013544254A5/ja
Application granted granted Critical
Publication of JP6306886B2 publication Critical patent/JP6306886B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013539982A 2010-11-17 2011-11-16 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 Expired - Fee Related JP6306886B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/948,329 US8648046B2 (en) 2009-02-26 2010-11-17 Compositions and methods for visualizing and eliminating cancer stem cells
US12/948,329 2010-11-17
PCT/US2011/061040 WO2012068282A1 (en) 2010-11-17 2011-11-16 Use of prolactin receptor antagonist and chemotherapeutic drug for treating ovarian cancer

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2015227552A Division JP2016029110A (ja) 2010-11-17 2015-11-20 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用
JP2018008262A Division JP2018062527A (ja) 2010-11-17 2018-01-22 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用

Publications (3)

Publication Number Publication Date
JP2013544254A JP2013544254A (ja) 2013-12-12
JP2013544254A5 true JP2013544254A5 (https=) 2014-12-18
JP6306886B2 JP6306886B2 (ja) 2018-04-04

Family

ID=45349276

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013539982A Expired - Fee Related JP6306886B2 (ja) 2010-11-17 2011-11-16 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用
JP2015227552A Pending JP2016029110A (ja) 2010-11-17 2015-11-20 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用
JP2018008262A Withdrawn JP2018062527A (ja) 2010-11-17 2018-01-22 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015227552A Pending JP2016029110A (ja) 2010-11-17 2015-11-20 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用
JP2018008262A Withdrawn JP2018062527A (ja) 2010-11-17 2018-01-22 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用

Country Status (9)

Country Link
US (2) US8648046B2 (https=)
EP (1) EP2640412B1 (https=)
JP (3) JP6306886B2 (https=)
KR (1) KR20140009196A (https=)
CN (2) CN103298481A (https=)
AU (1) AU2011328935B2 (https=)
CA (1) CA2817846A1 (https=)
IL (1) IL226271A (https=)
WO (1) WO2012068282A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013167750A2 (en) * 2012-05-11 2013-11-14 Prorec Bio Ab Method for diagnosis and treatment of prolactin associated disorders
CN105102480B (zh) 2012-12-24 2019-04-16 艾伯维公司 催乳素受体结合蛋白及其用途
KR102359214B1 (ko) 2014-04-04 2022-02-07 델 마 파마슈티컬스 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
TW201836647A (zh) 2017-04-06 2018-10-16 美商艾伯維有限公司 抗-prlr抗體藥物軛合物(adc)及其用途
EP3707166A4 (en) * 2017-11-06 2021-11-24 Daniel J. Monticello CHEMICAL ANTIGENIC RECEPTOR SYSTEMS WITH NEGATIVE DOMINANT LIGAND
WO2019169330A1 (en) * 2018-03-02 2019-09-06 Oncolix, Inc. Method for treating cancers expressing prolactin receptor
UY39610A (es) 2021-01-20 2022-08-31 Abbvie Inc Conjugados anticuerpo-fármaco anti-egfr
CN113956356B (zh) * 2021-10-27 2023-05-02 福州迈新生物技术开发有限公司 抗prl蛋白单克隆抗体、细胞系及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1055932A (en) 1975-10-22 1979-06-05 Hematech Inc. Blood substitute based on hemoglobin
DE2616086C2 (de) 1976-04-13 1986-04-03 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Substanz zur Verwendung in einem kolloidalen Blutvolumenersatzmittel aus Hydroxyethylstärke und Hämoglobin
EP1079851B1 (en) * 1998-05-12 2007-07-04 Greenville Hospital System Use of anti-prolactin agents to treat cancer
EP2180054A1 (en) * 1999-12-24 2010-04-28 Genentech, Inc. Methods and compositions for prolonging elimination half-times of bioactive compounds
EP1282642B1 (en) * 2000-05-09 2006-09-06 Greenville Hospital System Therapeutic pore-forming peptides
US7001888B2 (en) * 2002-03-29 2006-02-21 Threshold Pharmaceuticals, Inc. Compositions and methods for treating cancer
BR0314106A (pt) 2002-09-11 2005-07-19 Fresenius Kabi De Gmbh Polipeptìdeos hasilados, especialmente eritropoietina hasilada
NZ541122A (en) * 2002-12-26 2008-09-26 Mountain View Pharmaceuticals Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
US8754031B2 (en) * 2004-03-08 2014-06-17 Oncolix, Inc. Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway
US20050238628A1 (en) * 2004-04-08 2005-10-27 Blau Carl A Methods for treating cancer
US7422899B2 (en) * 2005-10-05 2008-09-09 Biogen Idec Ma Inc. Antibodies to the human prolactin receptor
CN100479863C (zh) * 2006-09-06 2009-04-22 中国医学科学院北京协和医院 Cofilin 1与癌症的紫杉烷类化疗药物耐药性的相关性
EP2094291A1 (en) * 2006-12-21 2009-09-02 Novo Nordisk A/S Dimeric prolactin receptor ligands
WO2009089537A2 (en) * 2008-01-11 2009-07-16 Northwestern University Anti-cancer compounds
US8754035B2 (en) * 2009-02-26 2014-06-17 Oncolix, Inc. Compositions and methods for visualizing and eliminating cancer stem cells

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