JP6306886B2 - 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 - Google Patents
卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 Download PDFInfo
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- JP6306886B2 JP6306886B2 JP2013539982A JP2013539982A JP6306886B2 JP 6306886 B2 JP6306886 B2 JP 6306886B2 JP 2013539982 A JP2013539982 A JP 2013539982A JP 2013539982 A JP2013539982 A JP 2013539982A JP 6306886 B2 JP6306886 B2 JP 6306886B2
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- prolactin
- prolactin receptor
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- ovarian cancer
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Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2257—Prolactin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US12/948,329 US8648046B2 (en) | 2009-02-26 | 2010-11-17 | Compositions and methods for visualizing and eliminating cancer stem cells |
| US12/948,329 | 2010-11-17 | ||
| PCT/US2011/061040 WO2012068282A1 (en) | 2010-11-17 | 2011-11-16 | Use of prolactin receptor antagonist and chemotherapeutic drug for treating ovarian cancer |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| JP2015227552A Division JP2016029110A (ja) | 2010-11-17 | 2015-11-20 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2018008262A Division JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
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| JP2013544254A JP2013544254A (ja) | 2013-12-12 |
| JP2013544254A5 JP2013544254A5 (https=) | 2014-12-18 |
| JP6306886B2 true JP6306886B2 (ja) | 2018-04-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2013539982A Expired - Fee Related JP6306886B2 (ja) | 2010-11-17 | 2011-11-16 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2015227552A Pending JP2016029110A (ja) | 2010-11-17 | 2015-11-20 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2018008262A Withdrawn JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2015227552A Pending JP2016029110A (ja) | 2010-11-17 | 2015-11-20 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
| JP2018008262A Withdrawn JP2018062527A (ja) | 2010-11-17 | 2018-01-22 | 卵巣がんを治療するためのプロラクチン受容体拮抗薬および化学療法剤の使用 |
Country Status (9)
| Country | Link |
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| US (2) | US8648046B2 (https=) |
| EP (1) | EP2640412B1 (https=) |
| JP (3) | JP6306886B2 (https=) |
| KR (1) | KR20140009196A (https=) |
| CN (2) | CN103298481A (https=) |
| AU (1) | AU2011328935B2 (https=) |
| CA (1) | CA2817846A1 (https=) |
| IL (1) | IL226271A (https=) |
| WO (1) | WO2012068282A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013167750A2 (en) * | 2012-05-11 | 2013-11-14 | Prorec Bio Ab | Method for diagnosis and treatment of prolactin associated disorders |
| CN105102480B (zh) | 2012-12-24 | 2019-04-16 | 艾伯维公司 | 催乳素受体结合蛋白及其用途 |
| KR102359214B1 (ko) | 2014-04-04 | 2022-02-07 | 델 마 파마슈티컬스 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
| TW201836647A (zh) | 2017-04-06 | 2018-10-16 | 美商艾伯維有限公司 | 抗－ｐｒｌｒ抗體藥物軛合物（ａｄｃ）及其用途 |
| EP3707166A4 (en) * | 2017-11-06 | 2021-11-24 | Daniel J. Monticello | CHEMICAL ANTIGENIC RECEPTOR SYSTEMS WITH NEGATIVE DOMINANT LIGAND |
| WO2019169330A1 (en) * | 2018-03-02 | 2019-09-06 | Oncolix, Inc. | Method for treating cancers expressing prolactin receptor |
| UY39610A (es) | 2021-01-20 | 2022-08-31 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| CN113956356B (zh) * | 2021-10-27 | 2023-05-02 | 福州迈新生物技术开发有限公司 | 抗prl蛋白单克隆抗体、细胞系及其应用 |
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| CA1055932A (en) | 1975-10-22 | 1979-06-05 | Hematech Inc. | Blood substitute based on hemoglobin |
| DE2616086C2 (de) | 1976-04-13 | 1986-04-03 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg | Substanz zur Verwendung in einem kolloidalen Blutvolumenersatzmittel aus Hydroxyethylstärke und Hämoglobin |
| EP1079851B1 (en) * | 1998-05-12 | 2007-07-04 | Greenville Hospital System | Use of anti-prolactin agents to treat cancer |
| EP2180054A1 (en) * | 1999-12-24 | 2010-04-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| EP1282642B1 (en) * | 2000-05-09 | 2006-09-06 | Greenville Hospital System | Therapeutic pore-forming peptides |
| US7001888B2 (en) * | 2002-03-29 | 2006-02-21 | Threshold Pharmaceuticals, Inc. | Compositions and methods for treating cancer |
| BR0314106A (pt) | 2002-09-11 | 2005-07-19 | Fresenius Kabi De Gmbh | Polipeptìdeos hasilados, especialmente eritropoietina hasilada |
| NZ541122A (en) * | 2002-12-26 | 2008-09-26 | Mountain View Pharmaceuticals | Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity |
| US8754031B2 (en) * | 2004-03-08 | 2014-06-17 | Oncolix, Inc. | Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway |
| US20050238628A1 (en) * | 2004-04-08 | 2005-10-27 | Blau Carl A | Methods for treating cancer |
| US7422899B2 (en) * | 2005-10-05 | 2008-09-09 | Biogen Idec Ma Inc. | Antibodies to the human prolactin receptor |
| CN100479863C (zh) * | 2006-09-06 | 2009-04-22 | 中国医学科学院北京协和医院 | Cofilin 1与癌症的紫杉烷类化疗药物耐药性的相关性 |
| EP2094291A1 (en) * | 2006-12-21 | 2009-09-02 | Novo Nordisk A/S | Dimeric prolactin receptor ligands |
| WO2009089537A2 (en) * | 2008-01-11 | 2009-07-16 | Northwestern University | Anti-cancer compounds |
| US8754035B2 (en) * | 2009-02-26 | 2014-06-17 | Oncolix, Inc. | Compositions and methods for visualizing and eliminating cancer stem cells |
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2010
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2011
- 2011-11-16 CA CA2817846A patent/CA2817846A1/en not_active Abandoned
- 2011-11-16 US US13/988,014 patent/US20130231286A1/en not_active Abandoned
- 2011-11-16 WO PCT/US2011/061040 patent/WO2012068282A1/en not_active Ceased
- 2011-11-16 CN CN2011800552054A patent/CN103298481A/zh active Pending
- 2011-11-16 AU AU2011328935A patent/AU2011328935B2/en not_active Ceased
- 2011-11-16 KR KR1020137013005A patent/KR20140009196A/ko not_active Ceased
- 2011-11-16 EP EP11796851.1A patent/EP2640412B1/en not_active Not-in-force
- 2011-11-16 JP JP2013539982A patent/JP6306886B2/ja not_active Expired - Fee Related
- 2011-11-16 CN CN201610675696.7A patent/CN106177915A/zh active Pending
-
2013
- 2013-05-09 IL IL226271A patent/IL226271A/en active IP Right Grant
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2015
- 2015-11-20 JP JP2015227552A patent/JP2016029110A/ja active Pending
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2018
- 2018-01-22 JP JP2018008262A patent/JP2018062527A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016029110A (ja) | 2016-03-03 |
| CN106177915A (zh) | 2016-12-07 |
| IL226271A (en) | 2017-05-29 |
| KR20140009196A (ko) | 2014-01-22 |
| JP2013544254A (ja) | 2013-12-12 |
| US8648046B2 (en) | 2014-02-11 |
| WO2012068282A1 (en) | 2012-05-24 |
| EP2640412B1 (en) | 2017-08-02 |
| IL226271A0 (en) | 2013-07-31 |
| AU2011328935B2 (en) | 2016-08-11 |
| EP2640412A1 (en) | 2013-09-25 |
| JP2018062527A (ja) | 2018-04-19 |
| AU2011328935A1 (en) | 2013-05-30 |
| US20130231286A1 (en) | 2013-09-05 |
| CN103298481A (zh) | 2013-09-11 |
| US20110065639A1 (en) | 2011-03-17 |
| CA2817846A1 (en) | 2012-05-24 |
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