JP2013541586A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013541586A5 JP2013541586A5 JP2013537756A JP2013537756A JP2013541586A5 JP 2013541586 A5 JP2013541586 A5 JP 2013541586A5 JP 2013537756 A JP2013537756 A JP 2013537756A JP 2013537756 A JP2013537756 A JP 2013537756A JP 2013541586 A5 JP2013541586 A5 JP 2013541586A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pyrazin
- yloxy
- pyrazol
- piperidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41113710P | 2010-11-08 | 2010-11-08 | |
| US61/411,137 | 2010-11-08 | ||
| PCT/US2011/058692 WO2012064548A1 (en) | 2010-11-08 | 2011-11-01 | Compounds useful for inhibiting chk1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013541586A JP2013541586A (ja) | 2013-11-14 |
| JP2013541586A5 true JP2013541586A5 (https=) | 2014-12-18 |
| JP5792316B2 JP5792316B2 (ja) | 2015-10-07 |
Family
ID=45044707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537756A Active JP5792316B2 (ja) | 2010-11-08 | 2011-11-01 | Ｃｈｋ１を阻害するのに有用な化合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9067920B2 (https=) |
| EP (1) | EP2638033B1 (https=) |
| JP (1) | JP5792316B2 (https=) |
| KR (1) | KR101533166B1 (https=) |
| CN (1) | CN103180311B (https=) |
| AR (1) | AR083575A1 (https=) |
| AU (1) | AU2011326230B2 (https=) |
| BR (1) | BR112013010009B1 (https=) |
| CA (1) | CA2816944C (https=) |
| DK (1) | DK2638033T3 (https=) |
| EA (1) | EA022096B1 (https=) |
| ES (1) | ES2541414T3 (https=) |
| HR (1) | HRP20150530T1 (https=) |
| JO (1) | JO3145B1 (https=) |
| ME (1) | ME02119B (https=) |
| MX (1) | MX2013005181A (https=) |
| PL (1) | PL2638033T3 (https=) |
| PT (1) | PT2638033E (https=) |
| RS (1) | RS54012B1 (https=) |
| SI (1) | SI2638033T1 (https=) |
| TW (1) | TWI501956B (https=) |
| WO (1) | WO2012064548A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| CN108601781B (zh) | 2016-02-04 | 2019-11-22 | 广州必贝特医药技术有限公司 | 作为检测点激酶1(chk1)抑制剂的3,5-二取代吡唑及其制备及应用 |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| CN112457306A (zh) | 2019-09-06 | 2021-03-09 | 上海瑛派药业有限公司 | 3,5-二取代吡唑化合物作为激酶抑制剂及其应用 |
| TW202237586A (zh) * | 2020-11-30 | 2022-10-01 | 日商住友製藥股份有限公司 | 5-雜芳基-1h-吡唑-3-胺衍生物 |
| US11564920B2 (en) | 2020-11-30 | 2023-01-31 | Sumitomo Pharma Co., Ltd. | 5-heteroaryl-1H-pyrazol-3-amine derivative |
| US11932648B2 (en) | 2021-06-28 | 2024-03-19 | Blueprint Medicines Corporation | CDK2 inhibitors |
| AU2022421580A1 (en) | 2021-12-24 | 2024-07-18 | Sumitomo Pharma Co., Ltd. | 1h-pyrazole-3-amine derivative having bicyclic backbone |
| WO2023229032A1 (ja) * | 2022-05-27 | 2023-11-30 | 住友ファーマ株式会社 | 免疫チェックポイント阻害剤に対して治療抵抗性を示すがんの治療薬 |
| KR20260010389A (ko) * | 2023-04-14 | 2026-01-20 | 블루프린트 메디신즈 코포레이션 | Cdk2 억제제 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0412820A (pt) * | 2003-07-25 | 2006-09-26 | Pfizer | compostos de aminopirazol e utilização como inibidores de chk1 |
| ATE501138T1 (de) * | 2004-01-05 | 2011-03-15 | Astrazeneca Ab | Thiophenderivate als chk-1-inhibitoren |
| PL1756084T3 (pl) * | 2004-06-04 | 2009-06-30 | Arena Pharm Inc | Podstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie zaburzeń z metabolizmem związanych |
| CN101218229A (zh) * | 2005-05-05 | 2008-07-09 | 阿斯利康(瑞典)有限公司 | 吡唑基-氨基取代的嘧啶及其在癌症治疗中的应用 |
| EP1893607A4 (en) * | 2005-06-09 | 2010-07-21 | Merck Sharp & Dohme | CHECKPOINT KINASE INHIBITORS |
| WO2008117050A1 (en) * | 2007-03-27 | 2008-10-02 | Astrazeneca Ab | Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer |
| PA8850801A1 (es) * | 2008-12-17 | 2010-07-27 | Lilly Co Eli | Compuestos útiles para inhibir chk1 |
-
2011
- 2011-10-27 JO JOP/2011/0323A patent/JO3145B1/ar active
- 2011-10-27 AR ARP110103973A patent/AR083575A1/es active IP Right Grant
- 2011-10-28 TW TW100139492A patent/TWI501956B/zh active
- 2011-11-01 BR BR112013010009-5A patent/BR112013010009B1/pt active IP Right Grant
- 2011-11-01 PT PT117882639T patent/PT2638033E/pt unknown
- 2011-11-01 KR KR1020137011808A patent/KR101533166B1/ko active Active
- 2011-11-01 EA EA201390499A patent/EA022096B1/ru not_active IP Right Cessation
- 2011-11-01 ME MEP-2015-69A patent/ME02119B/me unknown
- 2011-11-01 CN CN201180053779.8A patent/CN103180311B/zh active Active
- 2011-11-01 WO PCT/US2011/058692 patent/WO2012064548A1/en not_active Ceased
- 2011-11-01 PL PL11788263T patent/PL2638033T3/pl unknown
- 2011-11-01 SI SI201130467T patent/SI2638033T1/sl unknown
- 2011-11-01 AU AU2011326230A patent/AU2011326230B2/en active Active
- 2011-11-01 US US13/877,923 patent/US9067920B2/en active Active
- 2011-11-01 MX MX2013005181A patent/MX2013005181A/es active IP Right Grant
- 2011-11-01 EP EP11788263.9A patent/EP2638033B1/en active Active
- 2011-11-01 ES ES11788263.9T patent/ES2541414T3/es active Active
- 2011-11-01 RS RS20150352A patent/RS54012B1/sr unknown
- 2011-11-01 HR HRP20150530TT patent/HRP20150530T1/hr unknown
- 2011-11-01 DK DK11788263T patent/DK2638033T3/en active
- 2011-11-01 CA CA2816944A patent/CA2816944C/en active Active
- 2011-11-01 JP JP2013537756A patent/JP5792316B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013541586A5 (https=) | ||
| ME02119B (me) | Spojevi korisni za inhibiranje chk1 | |
| HRP20130167T1 (hr) | Spojevi korisni za inhibiranje chk1 | |
| PH12021550418A1 (en) | Macrocycles with hetrocyclic p2` groups as factor xia inhibitors | |
| RU2015154275A (ru) | Комбинации антитела против pd-l1 и ингибитора mek и/или ингибитора braf | |
| JP2020517616A5 (https=) | ||
| MX2014012695A (es) | Derivados de isoindolona. | |
| CN107548391A (zh) | 嘧啶或吡啶类化合物、其制备方法和医药用途 | |
| MX2014012741A (es) | Derivados de imidazotiadiazol e imidazopirazina como inhibidores del receptor 4 activado de proteasa (par4) para tratamiento de agregacion plaquetaria. | |
| TN2017000511A1 (en) | New hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them. | |
| JP2017509586A5 (https=) | ||
| MX2014012454A (es) | Derivados de imidazotiadiazol como inhibidores del receptor 4 activado de proteasa (par4) para el tratamiento de agregacion plaquetaria. | |
| NZ626942A (en) | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | |
| TR201904658T4 (tr) | Bisiklik füzyonla birleştirilmiş heteroaril veya aril bileşikleri ve bunların ırak4 inhibitörleri olarak kullanımları. | |
| WO2014152389A8 (en) | Imaging agent for detection of diseased cells | |
| HK1208681A1 (en) | Pyridinone and pyridazinone derivatives | |
| JO3115B1 (ar) | مركبات بيريدازينون واستخدامها كمثبطات daao | |
| GEP201706778B (en) | Pyridinyl and fused pyridinyl triazolone derivatives | |
| JP2009536652A5 (https=) | ||
| UY30310A1 (es) | Derivados 2-azetidinona, sales, solvatos, composiciones farmacéuticas conteniéndolos, procesos de preparacion y aplicaciones | |
| JP2017532360A5 (https=) | ||
| JP2017519027A5 (https=) | ||
| JP2016507575A5 (https=) | ||
| NZ731966A (en) | Novel imaging composition and uses thereof | |
| MY194116A (en) | Pharmaceutical compounds |