JP2013540439A5 - - Google Patents
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- Publication number
- JP2013540439A5 JP2013540439A5 JP2013530355A JP2013530355A JP2013540439A5 JP 2013540439 A5 JP2013540439 A5 JP 2013540439A5 JP 2013530355 A JP2013530355 A JP 2013530355A JP 2013530355 A JP2013530355 A JP 2013530355A JP 2013540439 A5 JP2013540439 A5 JP 2013540439A5
- Authority
- JP
- Japan
- Prior art keywords
- shear region
- sample
- channel
- shear
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 239000012530 fluid Substances 0.000 claims 6
- 238000011084 recovery Methods 0.000 claims 6
- 239000000919 ceramic Substances 0.000 claims 2
- 230000009089 cytolysis Effects 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000013467 fragmentation Methods 0.000 claims 2
- 238000006062 fragmentation reaction Methods 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000010979 ruby Substances 0.000 claims 2
- 229910001750 ruby Inorganic materials 0.000 claims 2
- 229910052594 sapphire Inorganic materials 0.000 claims 2
- 239000010980 sapphire Substances 0.000 claims 2
- 238000010008 shearing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38639210P | 2010-09-24 | 2010-09-24 | |
| US61/386,392 | 2010-09-24 | ||
| PCT/US2011/052959 WO2012040571A2 (en) | 2010-09-24 | 2011-09-23 | Method and apparatus for fragmenting nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013540439A JP2013540439A (ja) | 2013-11-07 |
| JP2013540439A5 true JP2013540439A5 (https=) | 2014-11-06 |
| JP5791724B2 JP5791724B2 (ja) | 2015-10-07 |
Family
ID=45871060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013530355A Active JP5791724B2 (ja) | 2010-09-24 | 2011-09-23 | 核酸を断片化する方法及び装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9108194B2 (https=) |
| EP (1) | EP2619302B1 (https=) |
| JP (1) | JP5791724B2 (https=) |
| WO (1) | WO2012040571A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011054474B4 (de) * | 2011-07-20 | 2014-02-13 | Stratec Biomedical Ag | System zur Stabilisierung, Aufbewahrung und Lagerung einer Nukleinsäure |
| US20140370499A1 (en) * | 2011-12-23 | 2014-12-18 | The Broad Institute, Inc. | Device and method for fragmenting polymers and particles |
| AU2013202805B2 (en) * | 2013-03-14 | 2015-07-16 | Gen-Probe Incorporated | System and method for extending the capabilities of a diagnostic analyzer |
| JP6410464B2 (ja) * | 2014-05-12 | 2018-10-24 | 三井電気精機株式会社 | Ｄｎａ断片化装置及びｄｎａ断片化方法 |
| WO2016145039A1 (en) | 2015-03-10 | 2016-09-15 | Rubicon Genomics, Inc. | Enhanced fragmentation and repair of nucleic acids |
| KR102701140B1 (ko) * | 2022-07-25 | 2024-09-02 | 주식회사 제론셀베인 | 균일한 크기의 핵산 단편 제조 방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0552290B1 (en) | 1990-10-11 | 2000-02-02 | Advanced Research & Technology Institute | Process and apparatus for fragmenting biomaterials |
| JPH08295025A (ja) * | 1995-04-26 | 1996-11-12 | Hitachi Ltd | インクジェット記録装置 |
| US5846832A (en) * | 1995-09-20 | 1998-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for shear breakage of polynucleotides |
| US6622335B1 (en) * | 2000-03-29 | 2003-09-23 | Lam Research Corporation | Drip manifold for uniform chemical delivery |
| CA2419961A1 (en) * | 2000-08-18 | 2002-02-28 | Integrigen, Inc. | Methods and compositions for directed molecular evolution using dna-end modification |
| GB2394912B (en) | 2002-11-01 | 2006-07-12 | Norchip As | A microfabricated fluidic device for fragmentation |
| AU2003278682B2 (en) * | 2002-11-18 | 2007-07-19 | Agency For Science, Technology And Research | Method and system for cell and/or nucleic acid molecules isolation |
| US20060133957A1 (en) * | 2003-01-17 | 2006-06-22 | Knapp Merrill A | Device and method for fragmenting material by hydrodynamic shear |
| JP4338139B2 (ja) * | 2005-03-29 | 2009-10-07 | ツネイシホールディングス株式会社 | 液滴噴射ノズル |
| EP2250286A1 (en) | 2008-02-15 | 2010-11-17 | Life Technologies Corporation | Methods and compositions for shearing of polymers by sonication |
| US8252250B2 (en) * | 2008-11-26 | 2012-08-28 | Illumina, Inc. | Electroosmotic pump with improved gas management |
-
2011
- 2011-09-23 JP JP2013530355A patent/JP5791724B2/ja active Active
- 2011-09-23 EP EP11827604.7A patent/EP2619302B1/en active Active
- 2011-09-23 US US13/242,665 patent/US9108194B2/en active Active
- 2011-09-23 WO PCT/US2011/052959 patent/WO2012040571A2/en not_active Ceased
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