FR3042990B1 - Adaptateur microfluidique couplant deux zones d'ecoulement - Google Patents

Adaptateur microfluidique couplant deux zones d'ecoulement Download PDF

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Publication number
FR3042990B1
FR3042990B1 FR1560416A FR1560416A FR3042990B1 FR 3042990 B1 FR3042990 B1 FR 3042990B1 FR 1560416 A FR1560416 A FR 1560416A FR 1560416 A FR1560416 A FR 1560416A FR 3042990 B1 FR3042990 B1 FR 3042990B1
Authority
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France
Prior art keywords
microfluidic
chamber
liquid
adapter coupling
flow zones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1560416A
Other languages
English (en)
Other versions
FR3042990A1 (fr
Inventor
Anne-Gaelle Bourdat
Dulk Remco Den
Melanie Flaender
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR1560416A priority Critical patent/FR3042990B1/fr
Priority to EP16196304.6A priority patent/EP3162441A1/fr
Publication of FR3042990A1 publication Critical patent/FR3042990A1/fr
Application granted granted Critical
Publication of FR3042990B1 publication Critical patent/FR3042990B1/fr
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention porte sur un adaptateur microfluidique adapté pour coupler une première zone d'écoulement à une deuxième zone d'écoulement, comportant : - une chambre microfluidique (3) de volume prédéterminé, - une entrée microfluidique (5) débouchant dans une première partie (37) de ladite chambre (3), ladite entrée microfluidique (5) étant configurée pour admettre un liquide dans ladite chambre microfluidique (3) selon un premier mode d'écoulement, - un évent (9) disposé dans une seconde partie (39) de ladite chambre microfluidique (3), ledit évent étant configuré pour évacuer l'air s'échappant des bulles d'air contenues dans ledit liquide lors d'un éclatement des bulles interfaciales, et - une sortie microfluidique (7) disposée dans la première partie (37) de la chambre microfluidique (3), ladite sortie microfluidique étant configurée pour évacuer ledit liquide libéré de ses bulles d'air selon un deuxième mode d'écoulement.
FR1560416A 2015-10-30 2015-10-30 Adaptateur microfluidique couplant deux zones d'ecoulement Active FR3042990B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1560416A FR3042990B1 (fr) 2015-10-30 2015-10-30 Adaptateur microfluidique couplant deux zones d'ecoulement
EP16196304.6A EP3162441A1 (fr) 2015-10-30 2016-10-28 Dispositif microfluidique couplant deux zones d'écoulement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1560416A FR3042990B1 (fr) 2015-10-30 2015-10-30 Adaptateur microfluidique couplant deux zones d'ecoulement

Publications (2)

Publication Number Publication Date
FR3042990A1 FR3042990A1 (fr) 2017-05-05
FR3042990B1 true FR3042990B1 (fr) 2021-01-01

Family

ID=55025218

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1560416A Active FR3042990B1 (fr) 2015-10-30 2015-10-30 Adaptateur microfluidique couplant deux zones d'ecoulement

Country Status (2)

Country Link
EP (1) EP3162441A1 (fr)
FR (1) FR3042990B1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3068027B1 (fr) * 2017-06-26 2023-03-10 Commissariat Energie Atomique Dispositif microfluidique a plusieurs chambres en parallele
US11458467B2 (en) 2019-08-06 2022-10-04 Bio-Rad Laboratories Inc. Structures to define flow confinement shape and confinement stability with uniform aspiration
US11130125B2 (en) 2019-08-06 2021-09-28 Bio-Rad Laboratories, Inc. Prevention and bubble removal from microfluidic devices
CN113030452B (zh) * 2021-03-02 2022-11-08 南京信息工程大学 用于微量液体分析的蒸发效应补偿装置及其工作方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011079698B4 (de) * 2011-07-25 2022-08-04 Robert Bosch Gmbh Mikrofluidische Vorrichtung mit einer Kammer zur Lagerung einer Flüssigkeit
JP2015166707A (ja) * 2014-03-04 2015-09-24 キヤノン株式会社 マイクロ流路デバイス

Also Published As

Publication number Publication date
EP3162441A1 (fr) 2017-05-03
FR3042990A1 (fr) 2017-05-05

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