JP2013538864A - 生物活性アミノ酸配列及びその使用 - Google Patents

生物活性アミノ酸配列及びその使用 Download PDF

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Publication number
JP2013538864A
JP2013538864A JP2013532197A JP2013532197A JP2013538864A JP 2013538864 A JP2013538864 A JP 2013538864A JP 2013532197 A JP2013532197 A JP 2013532197A JP 2013532197 A JP2013532197 A JP 2013532197A JP 2013538864 A JP2013538864 A JP 2013538864A
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Prior art keywords
hrgd
hydrogel
sequence
cell
peptide
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Japanese (ja)
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JP2013538864A5 (enExample
Inventor
ローラン ジャニン
ロラン カレンズ
ワファ ムサ
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ソルヴェイ（ソシエテ アノニム）
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Publication of JP2013538864A publication Critical patent/JP2013538864A/ja
Publication of JP2013538864A5 publication Critical patent/JP2013538864A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F122/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
    • C08F122/36—Amides or imides
    • C08F122/38—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2013532197A 2010-10-08 2011-10-06 生物活性アミノ酸配列及びその使用 Pending JP2013538864A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10187070.7 2010-10-08
EP10187070 2010-10-08
EP10187069.9 2010-10-08
EP10187069 2010-10-08
PCT/EP2011/067481 WO2012045824A1 (en) 2010-10-08 2011-10-06 A bioactive amino acid sequence and use therefrom

Publications (2)

Publication Number Publication Date
JP2013538864A true JP2013538864A (ja) 2013-10-17
JP2013538864A5 JP2013538864A5 (enExample) 2014-11-13

Family

ID=45927243

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013532197A Pending JP2013538864A (ja) 2010-10-08 2011-10-06 生物活性アミノ酸配列及びその使用

Country Status (4)

Country Link
US (2) US20130210147A1 (enExample)
EP (2) EP2625191A1 (enExample)
JP (1) JP2013538864A (enExample)
WO (2) WO2012045822A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014019971A1 (en) 2012-08-01 2014-02-06 Peptisyntha Sa Peptides comprising a short-chain polyethylene glycol moiety
EP2692361A1 (en) * 2012-08-01 2014-02-05 Peptisyntha Sa Peptides comprising a short-chain polyethylene glycol moiety
EP2698429A1 (en) * 2012-08-17 2014-02-19 Centre National de la Recherche Scientifique (CNRS) Support for the culture of adherent cells and method for their detachment
US10130735B2 (en) * 2012-09-21 2018-11-20 Technologias Avanzadas Inspiralia S.L. Scaffold for cardiac patch
US20160243281A1 (en) * 2013-10-04 2016-08-25 The Regents Of The University Of California Hyaluronic acid and alginate hydrogel composition
WO2015103643A2 (en) 2014-01-06 2015-07-09 The General Hospital Corporation Integrin antagonists
EP3071591B1 (en) 2014-01-22 2021-05-05 Agency For Science, Technology And Research Antimicrobial peptidomimetics
US10195313B2 (en) 2014-04-10 2019-02-05 Wisconsin Alumni Research Foundation Method for forming hydrogel arrays using surfaces with differential wettability
CN107629129B (zh) * 2016-07-19 2023-08-04 清华大学 生产和纯化多肽的方法
US11001656B2 (en) * 2016-07-29 2021-05-11 Phillips 66 Company Method of forming thermoresponsive polymers
EP3561001B1 (en) * 2016-12-20 2025-06-25 National University Corporation Hokkaido University Temperature-responsive gel having lcst with no volume phase transition, and production method therefor
US20210146003A1 (en) * 2017-06-16 2021-05-20 University Of Southern California A novel method to improve adhesive strength of reversible polymers and hydrogels
WO2020048996A1 (en) 2018-09-06 2020-03-12 ETH Zürich Self-assembling globular proteins and uses thereof
GB2614162B (en) * 2020-09-09 2024-11-06 Social Profit Network Methods and compositions for delivery of biotin to mitochondria
CN113621028A (zh) * 2021-07-27 2021-11-09 南通大学 一种多肽自组装水凝胶支架及其应用
CN115948322B (zh) * 2021-10-09 2024-07-02 中国科学院上海药物研究所 一种单层自组装多肽溶液培养细胞的方法
CN115925786B (zh) * 2022-08-29 2025-03-21 青岛科技大学 一种多肽、多肽复合水凝胶及其制备方法和应用
WO2024155651A2 (en) * 2023-01-17 2024-07-25 Rutgers, The State University Of New Jersey Nanosheet-hydrogel composites and methods of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515796A (ja) * 2001-02-06 2005-06-02 マサチューセッツ　インスティテュート　オブ　テクノロジー ペプチド足場での組織細胞のカプセル化およびその使用
JP2010504972A (ja) * 2006-09-26 2010-02-18 マサチューセッツ・インスティテュート・オブ・テクノロジー 修飾自己組織化ペプチド

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US5677276A (en) * 1994-12-23 1997-10-14 La Jolla Cancer Research Foundation Immobilization of peptides to hyaluronate
US7449180B2 (en) * 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
US7713923B2 (en) 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515796A (ja) * 2001-02-06 2005-06-02 マサチューセッツ　インスティテュート　オブ　テクノロジー ペプチド足場での組織細胞のカプセル化およびその使用
JP2010504972A (ja) * 2006-09-26 2010-02-18 マサチューセッツ・インスティテュート・オブ・テクノロジー 修飾自己組織化ペプチド

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6015038645; Ｐｅｐｔｉｄｅ　Ｓｃｉｅｎｃｅ　２０００ Ｖｏｌ．３７, 2001, ｐ．３３３-３３６ *
JPN6015038647; Ｂｉｏｍａｃｒｏｍｏｌｅｃｕｌｅｓ Ｖｏｌ．７, 2006, ｐ．３８-４７ *
JPN6015038649; Ｂｉｏｔｅｃｈｎｏｌｏｇｙ　Ｌｅｔｔｅｒｓ Ｖｏｌ．２７, 2005, ｐ．２２７-２３１ *

Also Published As

Publication number Publication date
EP2625191A1 (en) 2013-08-14
US20130281602A1 (en) 2013-10-24
WO2012045822A1 (en) 2012-04-12
US20130210147A1 (en) 2013-08-15
WO2012045824A1 (en) 2012-04-12
EP2625192A1 (en) 2013-08-14

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