JP2013537915A - オピオイドの制御放出製剤 - Google Patents
オピオイドの制御放出製剤 Download PDFInfo
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- JP2013537915A JP2013537915A JP2013530379A JP2013530379A JP2013537915A JP 2013537915 A JP2013537915 A JP 2013537915A JP 2013530379 A JP2013530379 A JP 2013530379A JP 2013530379 A JP2013530379 A JP 2013530379A JP 2013537915 A JP2013537915 A JP 2013537915A
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- oxycodone
- salt
- opioid
- hours
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38622710P | 2010-09-24 | 2010-09-24 | |
| US61/386,227 | 2010-09-24 | ||
| US13/024,319 US20110195989A1 (en) | 2010-02-09 | 2011-02-09 | Controlled Release Formulations of Opioids |
| US13/024,319 | 2011-02-09 | ||
| PCT/US2011/053132 WO2012040651A2 (en) | 2010-09-24 | 2011-09-23 | Controlled release formulations of opioids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013537915A true JP2013537915A (ja) | 2013-10-07 |
| JP2013537915A5 JP2013537915A5 (https=) | 2014-11-06 |
Family
ID=44741728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013530379A Pending JP2013537915A (ja) | 2010-09-24 | 2011-09-23 | オピオイドの制御放出製剤 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2618820A2 (https=) |
| JP (1) | JP2013537915A (https=) |
| CN (1) | CN103476403A (https=) |
| AU (1) | AU2011305161A1 (https=) |
| CA (1) | CA2812570A1 (https=) |
| WO (1) | WO2012040651A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017521448A (ja) * | 2014-07-17 | 2017-08-03 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド | 即時放出性乱用抑止性液体充填剤形 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1429744A1 (en) | 2001-09-21 | 2004-06-23 | Egalet A/S | Morphine polymer release system |
| US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
| WO2004084868A1 (en) | 2003-03-26 | 2004-10-07 | Egalet A/S | Morphine controlled release system |
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| NZ597283A (en) | 2009-06-24 | 2013-07-26 | Egalet Ltd | Controlled release formulations |
| AU2013204592A1 (en) * | 2012-04-09 | 2013-10-24 | QRxPharma Ltd. | Controlled release formulations of opioids |
| AU2013285988A1 (en) | 2012-07-06 | 2015-02-12 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
| AU2018390826B2 (en) | 2017-12-20 | 2024-09-12 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| CN114515282B (zh) * | 2020-11-19 | 2023-09-08 | 山东大学 | Sorbic acid在制备抗冠状病毒感染药物中的应用 |
Citations (6)
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| JPH10508608A (ja) * | 1994-11-04 | 1998-08-25 | ユーロ−セルティーク，エス．エイ． | 溶融押出しによる経口投与可能なオピオイド製剤 |
| JP2002532410A (ja) * | 1998-12-17 | 2002-10-02 | ユーロ−セルティーク，エス．エイ． | 急速に効果を発揮し且つ効果的な血漿薬物濃度が急速に低下する制御放出性製剤 |
| US20030092724A1 (en) * | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| JP2004528338A (ja) * | 2001-05-02 | 2004-09-16 | ユーロ−セルティーク，エス．エイ． | 一日に一回のオキシコドン製剤 |
| JP2006528976A (ja) * | 2003-05-12 | 2006-12-28 | スパーナス ファーマシューティカル インコーポレイテッド | 減少された乱用潜在性を有する薬物製剤 |
| US20090291975A1 (en) * | 2008-05-20 | 2009-11-26 | Warren Stern | Dual opioid pain therapy |
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|---|---|---|---|---|
| US20060240105A1 (en) * | 1998-11-02 | 2006-10-26 | Elan Corporation, Plc | Multiparticulate modified release composition |
| EP1450824A4 (en) * | 2001-11-02 | 2005-09-28 | Elan Corp Plc | PHARMACEUTICAL COMPOSITION |
| WO2006073396A1 (en) | 2005-01-05 | 2006-07-13 | Regents Of The University Of Minnesota | Analgesic conjugates |
| CN101151021A (zh) * | 2005-03-28 | 2008-03-26 | 奥瑞克索股份公司 | 用于疼痛治疗的新药物组合物 |
| US20090082466A1 (en) | 2006-01-27 | 2009-03-26 | Najib Babul | Abuse Resistant and Extended Release Formulations and Method of Use Thereof |
| JP2010509227A (ja) * | 2006-11-07 | 2010-03-25 | ネクター セラピューティックス エイエル，コーポレイション | オピオイド作動薬およびオピオイド拮抗薬の用量形態および同時投与 |
| US20110195989A1 (en) * | 2010-02-09 | 2011-08-11 | Rudnic Edward M | Controlled Release Formulations of Opioids |
-
2011
- 2011-09-23 EP EP11764653.9A patent/EP2618820A2/en not_active Withdrawn
- 2011-09-23 CA CA2812570A patent/CA2812570A1/en not_active Abandoned
- 2011-09-23 JP JP2013530379A patent/JP2013537915A/ja active Pending
- 2011-09-23 WO PCT/US2011/053132 patent/WO2012040651A2/en not_active Ceased
- 2011-09-23 AU AU2011305161A patent/AU2011305161A1/en not_active Abandoned
- 2011-09-23 CN CN2011800562785A patent/CN103476403A/zh active Pending
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| JP2002532410A (ja) * | 1998-12-17 | 2002-10-02 | ユーロ−セルティーク，エス．エイ． | 急速に効果を発揮し且つ効果的な血漿薬物濃度が急速に低下する制御放出性製剤 |
| JP2004528338A (ja) * | 2001-05-02 | 2004-09-16 | ユーロ−セルティーク，エス．エイ． | 一日に一回のオキシコドン製剤 |
| US20030092724A1 (en) * | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| JP2006528976A (ja) * | 2003-05-12 | 2006-12-28 | スパーナス ファーマシューティカル インコーポレイテッド | 減少された乱用潜在性を有する薬物製剤 |
| US20090291975A1 (en) * | 2008-05-20 | 2009-11-26 | Warren Stern | Dual opioid pain therapy |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017521448A (ja) * | 2014-07-17 | 2017-08-03 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド | 即時放出性乱用抑止性液体充填剤形 |
| JP2018197241A (ja) * | 2014-07-17 | 2018-12-13 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド | 即時放出性乱用抑止性液体充填剤形 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012040651A3 (en) | 2012-05-18 |
| CN103476403A (zh) | 2013-12-25 |
| EP2618820A2 (en) | 2013-07-31 |
| WO2012040651A2 (en) | 2012-03-29 |
| AU2011305161A1 (en) | 2013-05-09 |
| CA2812570A1 (en) | 2012-03-29 |
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