JP2013536169A5 - - Google Patents
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- Publication number
- JP2013536169A5 JP2013536169A5 JP2013519943A JP2013519943A JP2013536169A5 JP 2013536169 A5 JP2013536169 A5 JP 2013536169A5 JP 2013519943 A JP2013519943 A JP 2013519943A JP 2013519943 A JP2013519943 A JP 2013519943A JP 2013536169 A5 JP2013536169 A5 JP 2013536169A5
- Authority
- JP
- Japan
- Prior art keywords
- hesperetin
- composition
- skin microcirculation
- plant extract
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 claims 14
- AIONOLUJZLIMTK-AWEZNQCLSA-N hesperetin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O)=CC(O)=C2C(=O)C1 AIONOLUJZLIMTK-AWEZNQCLSA-N 0.000 claims 14
- 229960001587 hesperetin Drugs 0.000 claims 14
- AIONOLUJZLIMTK-UHFFFAOYSA-N hesperetin Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(O)=CC(O)=C2C(=O)C1 AIONOLUJZLIMTK-UHFFFAOYSA-N 0.000 claims 14
- 235000010209 hesperetin Nutrition 0.000 claims 14
- FTODBIPDTXRIGS-UHFFFAOYSA-N homoeriodictyol Natural products C1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 FTODBIPDTXRIGS-UHFFFAOYSA-N 0.000 claims 14
- 230000004089 microcirculation Effects 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 239000000419 plant extract Substances 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 4
- 235000020971 citrus fruits Nutrition 0.000 claims 4
- 239000000284 extract Substances 0.000 claims 4
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 2
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical group O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 claims 2
- 241000207199 Citrus Species 0.000 claims 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 2
- 150000007942 carboxylates Chemical class 0.000 claims 2
- 229960000541 cetyl alcohol Drugs 0.000 claims 2
- -1 dimethylsiloxane Chemical class 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 235000010445 lecithin Nutrition 0.000 claims 2
- 239000000787 lecithin Substances 0.000 claims 2
- 229940067606 lecithin Drugs 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- 239000000230 xanthan gum Substances 0.000 claims 2
- 229940082509 xanthan gum Drugs 0.000 claims 2
- 235000010493 xanthan gum Nutrition 0.000 claims 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 235000019437 butane-1,3-diol Nutrition 0.000 claims 1
- 210000000744 eyelid Anatomy 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010231389.2A CN102266320B (zh) | 2010-07-20 | 2010-07-20 | 橙皮素的新用途 |
| CN201010231389.2 | 2010-07-20 | ||
| PCT/CN2011/075765 WO2012010022A1 (zh) | 2010-07-20 | 2011-06-15 | 橙皮素的新用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013536169A JP2013536169A (ja) | 2013-09-19 |
| JP2013536169A5 true JP2013536169A5 (https=) | 2015-09-03 |
| JP5871921B2 JP5871921B2 (ja) | 2016-03-01 |
Family
ID=45048905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013519943A Active JP5871921B2 (ja) | 2010-07-20 | 2011-06-15 | ヘスペレチンの新規使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9351952B2 (https=) |
| EP (1) | EP2596787B1 (https=) |
| JP (1) | JP5871921B2 (https=) |
| KR (1) | KR101817514B1 (https=) |
| CN (1) | CN102266320B (https=) |
| WO (1) | WO2012010022A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6175067B2 (ja) | 2011-11-25 | 2017-08-02 | ナチュラル・メディシン・インスティチュート・オブ・ジャージアン・ヤンシェンタン・カンパニー・リミテッド | ネオヘスペリジンの新規の使用 |
| CN104188819B (zh) * | 2014-09-25 | 2016-08-03 | 山西医科大学 | 一种透明质酸分散的橙皮素纳米爽肤水及其制备方法 |
| WO2017038951A1 (ja) | 2015-09-02 | 2017-03-09 | 株式会社林原 | 黄ぐすみ低減用皮膚外用剤 |
| CN111888371A (zh) * | 2020-08-07 | 2020-11-06 | 广东工业大学 | 一种糖基化橙皮素化合物在制备缓解痛经制品中的应用 |
| CN115053963A (zh) * | 2022-06-28 | 2022-09-16 | 仙乐健康科技股份有限公司 | 一种提升体温和促进体表微循环的组合物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2159985C (en) * | 1993-04-20 | 1999-07-13 | Raphael Warren | Methods of using hesperetin for sebum control and treatment of acne |
| FR2778663B1 (fr) * | 1998-05-15 | 2001-05-18 | Coletica | Nouveaux esters de flavonoides,leur utilisation en cosmetique, dermopharmacie, en pharmacie et en agro-alimentaire |
| JP2001072564A (ja) * | 1999-09-08 | 2001-03-21 | Kanebo Ltd | くま改善剤 |
| US6607735B2 (en) * | 2000-12-21 | 2003-08-19 | Johnson & Johnson Consumer Companies, Inc. | Method for reducing the appearance of dark circles under the eyes |
| WO2003053336A2 (en) * | 2001-12-19 | 2003-07-03 | The Quigley Corporation | Methods for the treatment of peripheral neural and vascular ailments |
| FR2834639A1 (fr) | 2002-01-11 | 2003-07-18 | Medix Lab | Composition comprenant en association au moins un flavonoide et au moins une huile vegetale, son utilisation comme agent dermatologique ou dermatocosmetique |
| FR2836042B1 (fr) * | 2002-02-15 | 2004-04-02 | Sederma Sa | Compositions cosmetiques ou dermopharmaceutiques pour diminuer les poches et cernes sous les yeux |
| US20080008673A1 (en) * | 2006-07-03 | 2008-01-10 | Claudie Willemin | Compositions comprising at least one C-glycoside derivative |
| FR2919501B1 (fr) * | 2007-08-02 | 2010-12-31 | Oreal | Utilisation d'hesperidine ou de l'un de ses derives pour la prevention et/ou le traitement des peaux relachees |
| JP5551582B2 (ja) * | 2008-03-17 | 2014-07-16 | 株式会社林原 | 皮膚外用剤 |
| CA2749750C (en) | 2008-04-15 | 2014-01-28 | Immanence Integrale Dermo Correction Inc. | Skin care compositions and methods of use thereof |
| FR2933608B1 (fr) | 2008-07-11 | 2014-01-10 | Lvmh Rech | Nouvelle utilisation d'un extrait de grande mauve agent hydratant, et composition cosmetique le contenant. |
| JP5203084B2 (ja) | 2008-07-30 | 2013-06-05 | 江崎グリコ株式会社 | 分散ヘスペレチン |
-
2010
- 2010-07-20 CN CN201010231389.2A patent/CN102266320B/zh active Active
-
2011
- 2011-06-15 US US13/810,828 patent/US9351952B2/en active Active
- 2011-06-15 EP EP11809210.5A patent/EP2596787B1/en active Active
- 2011-06-15 WO PCT/CN2011/075765 patent/WO2012010022A1/zh not_active Ceased
- 2011-06-15 KR KR1020137003693A patent/KR101817514B1/ko active Active
- 2011-06-15 JP JP2013519943A patent/JP5871921B2/ja active Active
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