JP2013534313A5 - - Google Patents
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- Publication number
- JP2013534313A5 JP2013534313A5 JP2013522346A JP2013522346A JP2013534313A5 JP 2013534313 A5 JP2013534313 A5 JP 2013534313A5 JP 2013522346 A JP2013522346 A JP 2013522346A JP 2013522346 A JP2013522346 A JP 2013522346A JP 2013534313 A5 JP2013534313 A5 JP 2013534313A5
- Authority
- JP
- Japan
- Prior art keywords
- hmgb1
- antibody
- stool sample
- protein
- ibd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM2010A000442A IT1406051B1 (it) | 2010-08-05 | 2010-08-05 | Uso di hmgb1 come marcatore biologico di infiammazione intestinale umana, metodo non invasivo per la sua rilevazione in campioni fecali e kit relativo. |
| ITRM2010A000442 | 2010-08-05 | ||
| PCT/IT2011/000276 WO2012017466A1 (en) | 2010-08-05 | 2011-08-01 | Use of hmgb1 as' a biological marker of bowel inflammatory conditions, non-invasive method for its detection in fecal samples and kit thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013534313A JP2013534313A (ja) | 2013-09-02 |
| JP2013534313A5 true JP2013534313A5 (https=) | 2014-09-18 |
Family
ID=43739596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013522346A Pending JP2013534313A (ja) | 2010-08-05 | 2011-08-01 | 腸の炎症状態の生物学的マーカーとしてのｈｍｇｂ１の使用、糞便サンプル中のｈｍｇｂ１を検出するための非侵襲法およびそのキット |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20130137123A1 (https=) |
| EP (1) | EP2601525A1 (https=) |
| JP (1) | JP2013534313A (https=) |
| CN (1) | CN103069276A (https=) |
| AU (1) | AU2011287193B2 (https=) |
| BR (1) | BR112013002145A2 (https=) |
| CA (1) | CA2807107C (https=) |
| CL (1) | CL2013000223A1 (https=) |
| EA (1) | EA201390197A1 (https=) |
| IL (1) | IL223845A (https=) |
| IT (1) | IT1406051B1 (https=) |
| MX (1) | MX2013001327A (https=) |
| PE (1) | PE20131062A1 (https=) |
| WO (1) | WO2012017466A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015067913A1 (en) | 2013-11-07 | 2015-05-14 | Diagnodus Limited | Biomarkers |
| DK2968443T3 (da) | 2013-03-15 | 2021-12-06 | Protagonist Therapeutics Inc | Hepcidinanaloger og anvendelser deraf |
| PT3143037T (pt) | 2014-05-16 | 2021-09-24 | Protagonist Therapeutics Inc | Antagonistas peptídicos tioéter de integrina alfa4beta7 |
| US9624268B2 (en) | 2014-07-17 | 2017-04-18 | Protagonist Therapeutics, Inc. | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| US20200064357A1 (en) * | 2016-11-09 | 2020-02-27 | Protagonist Therapeutics, Inc. | Methods for determining and monitoring gastrointestinal inflammation |
| PL3622082T3 (pl) | 2017-05-12 | 2023-07-31 | Evonik Operations Gmbh | Sposób wykrywania chorób wywołanych przez C. perfringens w stadzie ptaków |
| IT201700083044A1 (it) | 2017-07-20 | 2019-01-20 | Laura Stronati | “uso della gelsolina come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali” |
| IT201700083055A1 (it) | 2017-07-20 | 2019-01-20 | Laura Stronati | “uso della proteina inibitore 2 della dissociazione di rho gdp come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali” |
| EP3749345A4 (en) | 2018-02-08 | 2022-04-06 | Protagonist Therapeutics, Inc. | CONJUGATED HEPCIDIN MIMETICS |
| US12031991B2 (en) * | 2018-03-02 | 2024-07-09 | Evonik Operations Gmbh | In vitro method for detecting intestinal barrier failure in animals |
| CN109030817A (zh) * | 2018-07-04 | 2018-12-18 | 长沙都正医学检验有限责任公司 | Hmgb1检测试剂盒及其制备方法 |
| TW202019948A (zh) | 2018-07-12 | 2020-06-01 | 美商領導醫療有限公司 | 介白素-23受體之肽抑制劑及其治療發炎疾病之用途 |
| DK3894863T3 (en) | 2018-12-14 | 2023-02-20 | Evonik Operations Gmbh | In vitro-fremgangsmåde til påvisning af aviær intestinal dysbiose |
| US11684653B2 (en) * | 2019-03-06 | 2023-06-27 | The Cleveland Clinic Foundation | Compositions and method for reducing virulence of microorganisms |
| HRP20250769T1 (hr) | 2020-01-15 | 2025-08-29 | Janssen Biotech, Inc. | Peptidni inhibitori receptora za interleukin-23 i njihova uporaba u liječenju upalnih bolesti |
| AU2021209086A1 (en) | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| AU2021383828A1 (en) | 2020-11-20 | 2023-07-06 | Janssen Pharmaceutica Nv | Compositions of peptide inhibitors of interleukin-23 receptor |
| WO2023288019A2 (en) | 2021-07-14 | 2023-01-19 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of interleukin-23 receptor |
| CN116973572B (zh) * | 2023-06-02 | 2025-03-07 | 东南大学附属中大医院 | 基于血、粪便铁蛋白检测评估肠屏障损伤严重程度的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6822078B2 (en) * | 1996-07-17 | 2004-11-23 | Kaneka Corp. | Diagnostic drugs for autoimmune diseases |
| US6355623B2 (en) * | 1998-09-24 | 2002-03-12 | Hopital-Sainte-Justine | Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage |
| US6303321B1 (en) * | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| US7700307B2 (en) * | 2003-03-08 | 2010-04-20 | Auvation Limited | Mitochondrial stress-70 protein markers for colorectal cancer |
| US7585504B2 (en) * | 2004-10-22 | 2009-09-08 | Medimmune, Llc | High affinity antibodies against HMGB1 and methods of use thereof |
| US20090297546A1 (en) * | 2006-12-20 | 2009-12-03 | Shino-Test Corporation | Avian-derived antibody capable of binding specifically to human hmgb1, immunological determination method for human hmgb1, and immunological determination reagent for human hmgb1 |
| EA201000131A1 (ru) * | 2007-08-02 | 2010-08-30 | АйЭсЭс ИММЬЮН СИСТЕМ СТИМУЛЕЙШН АБ | Диагностика, определение стадии и мониторинг воспалительного заболевания кишечника |
| US7879553B2 (en) * | 2008-03-14 | 2011-02-01 | Exagen Diagnostics, Inc. | Biomarkers for inflammatory bowel disease and irritable bowel syndrome |
-
2010
- 2010-08-05 IT ITRM2010A000442A patent/IT1406051B1/it active
-
2011
- 2011-08-01 BR BR112013002145A patent/BR112013002145A2/pt not_active IP Right Cessation
- 2011-08-01 WO PCT/IT2011/000276 patent/WO2012017466A1/en not_active Ceased
- 2011-08-01 EP EP11754539.2A patent/EP2601525A1/en not_active Withdrawn
- 2011-08-01 CA CA2807107A patent/CA2807107C/en not_active Expired - Fee Related
- 2011-08-01 MX MX2013001327A patent/MX2013001327A/es unknown
- 2011-08-01 US US13/814,294 patent/US20130137123A1/en not_active Abandoned
- 2011-08-01 JP JP2013522346A patent/JP2013534313A/ja active Pending
- 2011-08-01 CN CN2011800327624A patent/CN103069276A/zh active Pending
- 2011-08-01 EA EA201390197A patent/EA201390197A1/ru unknown
- 2011-08-01 PE PE2013000131A patent/PE20131062A1/es not_active Application Discontinuation
- 2011-08-01 AU AU2011287193A patent/AU2011287193B2/en not_active Ceased
-
2012
- 2012-12-24 IL IL223845A patent/IL223845A/en active IP Right Grant
-
2013
- 2013-01-23 CL CL2013000223A patent/CL2013000223A1/es unknown
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