JP2013532130A5 - - Google Patents
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- JP2013532130A5 JP2013532130A5 JP2013510364A JP2013510364A JP2013532130A5 JP 2013532130 A5 JP2013532130 A5 JP 2013532130A5 JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013532130 A5 JP2013532130 A5 JP 2013532130A5
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- JP
- Japan
- Prior art keywords
- represented
- compound
- pharmaceutically acceptable
- acceptable salt
- structural formula
- Prior art date
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- 150000001875 compounds Chemical class 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33499110P | 2010-05-14 | 2010-05-14 | |
| US61/334,991 | 2010-05-14 | ||
| US37074510P | 2010-08-04 | 2010-08-04 | |
| US61/370,745 | 2010-08-04 | ||
| US37586310P | 2010-08-22 | 2010-08-22 | |
| US61/375,863 | 2010-08-22 | ||
| PCT/US2011/036701 WO2011143669A2 (en) | 2010-05-14 | 2011-05-16 | Compositions and methods for treating neoplasia, inflammatory disease and other disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015049960A Division JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013532130A JP2013532130A (ja) | 2013-08-15 |
| JP2013532130A5 true JP2013532130A5 (enrdf_load_stackoverflow) | 2014-11-06 |
| JP5715241B2 JP5715241B2 (ja) | 2015-05-07 |
Family
ID=49052897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013510364A Active JP5715241B2 (ja) | 2010-05-14 | 2011-05-16 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
| JP2015049960A Active JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015049960A Active JP5937247B2 (ja) | 2010-05-14 | 2015-03-12 | 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (2) | JP5715241B2 (enrdf_load_stackoverflow) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3182721B2 (ja) | 1997-08-06 | 2001-07-03 | 理兆 上田 | 自動車のペダル装置 |
| JP5913292B2 (ja) * | 2010-05-14 | 2016-04-27 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | 代謝を調節する組成物および方法 |
| EP2571503B1 (en) | 2010-05-14 | 2015-01-07 | Dana-Farber Cancer Institute, Inc. | Compositions and their use in treating neoplasia, inflammatory disease and other disorders |
| MX2014015986A (es) * | 2012-06-25 | 2016-02-11 | Oncoethix Gmbh | Metodo para tratar linfoma utilizando compuestos de tienotriazolodiazepina. |
| CN105899212A (zh) * | 2013-08-06 | 2016-08-24 | 翁科埃斯克斯有限公司 | 利用β溴结构域抑制剂治疗弥漫性大B细胞淋巴瘤(DLBCL)的方法 |
| US11446309B2 (en) | 2013-11-08 | 2022-09-20 | Dana-Farber Cancer Institute, Inc. | Combination therapy for cancer using bromodomain and extra-terminal (BET) protein inhibitors |
| JP2017506666A (ja) | 2014-02-28 | 2017-03-09 | テンシャ セラピューティクス，インコーポレイテッド | 高インスリン血症に関連した症状の処置 |
| WO2016210275A1 (en) * | 2015-06-26 | 2016-12-29 | Tensha Therapeutics, Inc. | Treatment of nut midline carcinoma |
| US11306105B2 (en) * | 2015-09-11 | 2022-04-19 | Dana-Farber Cancer Institute, Inc. | Cyano thienotriazolodiazepines and uses thereof |
| CN108472299A (zh) * | 2015-09-11 | 2018-08-31 | 达纳-法伯癌症研究所股份有限公司 | 乙酰胺噻吩并三唑并二氮杂环庚三烯及其用途 |
| AU2016331190A1 (en) * | 2015-10-02 | 2018-04-12 | Dana-Farber Cancer Institute, Inc. | Combination therapy of bromodomain inhibitors and checkpoint blockade |
| CN109071562B (zh) * | 2016-02-15 | 2022-03-22 | 密执安大学评议会 | 作为bet溴结构域抑制剂的稠合1,4-氧氮杂䓬和相关类似物 |
| MX2019006956A (es) * | 2016-12-16 | 2019-08-01 | Hoffmann La Roche | Proceso para la fabricacion de derivados de diazepina. |
| CN109503618A (zh) * | 2017-09-14 | 2019-03-22 | 成都海创药业有限公司 | 一种brd4抑制剂 |
| WO2019238557A1 (en) * | 2018-06-13 | 2019-12-19 | Dybly Ag | Preparation of condensed triazepine derivatives and their use as bet inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1227555A (zh) * | 1996-06-12 | 1999-09-01 | 日本烟草产业株式会社 | 细胞因子生成抑制剂、三氮䓬化合物及其中间体 |
| US7589167B2 (en) * | 2000-02-22 | 2009-09-15 | J. David Gladstone Institutes | ZA loops of bromodomains |
| CA2515790C (en) * | 2003-02-27 | 2012-11-27 | Abbott Laboratories | Heterocyclic kinase inhibitors |
| CN101910182B (zh) * | 2007-12-28 | 2013-07-17 | 田边三菱制药株式会社 | 抗癌剂 |
| EA023441B1 (ru) * | 2009-11-05 | 2016-06-30 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | Бензодиазепиновый ингибитор бромодомена |
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2011
- 2011-05-16 JP JP2013510364A patent/JP5715241B2/ja active Active
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2015
- 2015-03-12 JP JP2015049960A patent/JP5937247B2/ja active Active