JP2013531619A5 - - Google Patents
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- Publication number
- JP2013531619A5 JP2013531619A5 JP2013509204A JP2013509204A JP2013531619A5 JP 2013531619 A5 JP2013531619 A5 JP 2013531619A5 JP 2013509204 A JP2013509204 A JP 2013509204A JP 2013509204 A JP2013509204 A JP 2013509204A JP 2013531619 A5 JP2013531619 A5 JP 2013531619A5
- Authority
- JP
- Japan
- Prior art keywords
- cadherin
- fibrosis
- pharmaceutical composition
- sample
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33135510P | 2010-05-04 | 2010-05-04 | |
| US33135710P | 2010-05-04 | 2010-05-04 | |
| US61/331,355 | 2010-05-04 | ||
| US61/331,357 | 2010-05-04 | ||
| PCT/US2011/035110 WO2011140173A1 (en) | 2010-05-04 | 2011-05-04 | Detection and treatment of fibrosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016066848A Division JP6437946B2 (ja) | 2010-05-04 | 2016-03-29 | 線維症の検出および処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531619A JP2013531619A (ja) | 2013-08-08 |
| JP2013531619A5 true JP2013531619A5 (enExample) | 2014-07-03 |
| JP5911848B2 JP5911848B2 (ja) | 2016-04-27 |
Family
ID=44904050
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509204A Active JP5911848B2 (ja) | 2010-05-04 | 2011-05-04 | 線維症の検出および処置 |
| JP2016066848A Expired - Fee Related JP6437946B2 (ja) | 2010-05-04 | 2016-03-29 | 線維症の検出および処置 |
| JP2018187200A Pending JP2019031513A (ja) | 2010-05-04 | 2018-10-02 | 線維症の検出および処置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016066848A Expired - Fee Related JP6437946B2 (ja) | 2010-05-04 | 2016-03-29 | 線維症の検出および処置 |
| JP2018187200A Pending JP2019031513A (ja) | 2010-05-04 | 2018-10-02 | 線維症の検出および処置 |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP3138915A1 (enExample) |
| JP (3) | JP5911848B2 (enExample) |
| KR (2) | KR20130107203A (enExample) |
| AU (3) | AU2011248184B2 (enExample) |
| CA (1) | CA2805267C (enExample) |
| ES (1) | ES2596431T3 (enExample) |
| IL (2) | IL222841B (enExample) |
| WO (1) | WO2011140173A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015201254A1 (en) * | 2010-06-04 | 2015-04-16 | The Brigham And Women's Hospital, Inc. | Treatment of inflammatory disorders |
| US20130209476A1 (en) * | 2010-06-04 | 2013-08-15 | The Brigham And Women's Hospital Inc. | Treatment of inflammatory disorders |
| CN104203280A (zh) * | 2012-03-27 | 2014-12-10 | 诺华股份有限公司 | 纤维化的治疗 |
| KR101497935B1 (ko) * | 2013-04-19 | 2015-03-03 | 경북대학교 산학협력단 | 루테올린을 유효성분으로 포함하는 섬유증의 예방 또는 치료용 조성물 |
| US11097005B2 (en) | 2014-12-15 | 2021-08-24 | The Brigham And Women's Hospital, Inc. | Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity |
| WO2021256837A1 (ko) | 2020-06-15 | 2021-12-23 | 인제대학교 산학협력단 | 신장 질환 진단 또는 치료용 조성물 |
| KR102404883B1 (ko) * | 2020-11-30 | 2022-06-07 | (주)이노보테라퓨틱스 | 벤즈브로마론을 포함하는 켈로이드 또는 비대흉터 예방 또는 치료용 약학 조성물 |
| WO2023034803A1 (en) * | 2021-08-30 | 2023-03-09 | The Brigham And Women's Hospital, Inc. | Methods for treatment of fibrosis |
| ES2957479B2 (es) | 2022-06-07 | 2025-07-28 | Baigene S L | Metodo de obtencion de datos utiles para la prediccion del riesgo de un sujeto de sufrir fibrosis |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US4355023A (en) | 1980-09-30 | 1982-10-19 | The Massachusetts General Hospital | Antibody fragment compositions and process |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4470925A (en) | 1982-05-05 | 1984-09-11 | E. I. Du Pont De Nemours And Company | Immunoglobulin half-molecules and process for producing hybrid antibodies |
| US4462334A (en) | 1982-08-19 | 1984-07-31 | Kim Ho K | Solar animal structure |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5565354A (en) | 1986-09-05 | 1996-10-15 | Sandoz Ltd. | Production of human monoclonal antibodies specific for hepatitis B surface antigen |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5391723A (en) | 1989-05-31 | 1995-02-21 | Neorx Corporation | Oligonucleotide conjugates |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| EP0464533B1 (de) | 1990-06-28 | 1998-07-29 | Hoechst Aktiengesellschaft | Fusionsproteine mit immunglobulinanteilen, ihre Herstellung und Verwendung |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| GB9019812D0 (en) | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
| US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
| DE69334275D1 (de) | 1992-08-21 | 2009-05-20 | Univ Bruxelles | Immunoglobuline ohne Leichtkette |
| US5645829A (en) | 1993-06-18 | 1997-07-08 | Beth Israel Hospital Association | Mesothelial cell gene therapy |
| EP0804249A2 (en) | 1994-03-15 | 1997-11-05 | Brown University Research Foundation | Polymeric gene delivery system |
| US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| US5898031A (en) | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| US6787136B1 (en) * | 1999-09-03 | 2004-09-07 | The Brigham And Women's Hospital, Inc. | Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents |
| KR20080023768A (ko) | 2000-03-30 | 2008-03-14 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체 |
| US20030190598A1 (en) | 2000-05-26 | 2003-10-09 | Jasmid Tanha | Single-domain antigen-binding antibody fragments derived from llama antibodies |
| CN100523215C (zh) | 2000-12-01 | 2009-08-05 | 马普科技促进协会 | 介导rna干涉的小rna分子 |
| JP2004245842A (ja) * | 2003-02-14 | 2004-09-02 | Seikagaku Kogyo Co Ltd | 嚢胞性肺線維症の評価方法 |
| GB0521621D0 (en) * | 2005-10-24 | 2005-11-30 | Domantis Ltd | Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases |
| EP2135078B1 (en) | 2007-03-09 | 2013-08-21 | DiscoveRx Corporation | Methods for identifying agents and their use for the prevention or stabilization of fibrosis |
| WO2009055864A1 (en) * | 2007-10-31 | 2009-05-07 | Crc For Asthma And Airways Ltd | Methods and compositions for regulating airway tissue remodelling |
| CA2711394A1 (en) * | 2008-01-11 | 2009-07-16 | Synovex Corporation | Cadherin-11 antagonists and methods for the treatment of inflammatory joint disorders |
| JP2011514318A (ja) * | 2008-02-11 | 2011-05-06 | ノバルティス アーゲー | カドヘリン１１（ｃｄｈ１１）アンタゴニストの使用方法 |
| US9599603B2 (en) * | 2008-07-16 | 2017-03-21 | Case Western Reserve University | Methods and compositions for modulating adhesion and migration of cadherin expressing cells |
-
2011
- 2011-05-04 KR KR1020127031805A patent/KR20130107203A/ko not_active Ceased
- 2011-05-04 ES ES11778233.4T patent/ES2596431T3/es active Active
- 2011-05-04 EP EP16177820.4A patent/EP3138915A1/en not_active Withdrawn
- 2011-05-04 CA CA2805267A patent/CA2805267C/en not_active Expired - Fee Related
- 2011-05-04 JP JP2013509204A patent/JP5911848B2/ja active Active
- 2011-05-04 KR KR1020187037089A patent/KR20190000385A/ko not_active Ceased
- 2011-05-04 WO PCT/US2011/035110 patent/WO2011140173A1/en not_active Ceased
- 2011-05-04 AU AU2011248184A patent/AU2011248184B2/en not_active Ceased
- 2011-05-04 EP EP11778233.4A patent/EP2566967B1/en not_active Not-in-force
-
2012
- 2012-11-04 IL IL222841A patent/IL222841B/en active IP Right Grant
-
2016
- 2016-03-15 AU AU2016201644A patent/AU2016201644B2/en not_active Ceased
- 2016-03-29 JP JP2016066848A patent/JP6437946B2/ja not_active Expired - Fee Related
-
2018
- 2018-01-14 AU AU2018200312A patent/AU2018200312A1/en not_active Abandoned
- 2018-10-02 JP JP2018187200A patent/JP2019031513A/ja active Pending
-
2019
- 2019-04-10 IL IL265950A patent/IL265950A/en unknown
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