JP2013528398A - ブタノール産生用の酵母生産培養物 - Google Patents

ブタノール産生用の酵母生産培養物 Download PDF

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Publication number
JP2013528398A
JP2013528398A JP2013515512A JP2013515512A JP2013528398A JP 2013528398 A JP2013528398 A JP 2013528398A JP 2013515512 A JP2013515512 A JP 2013515512A JP 2013515512 A JP2013515512 A JP 2013515512A JP 2013528398 A JP2013528398 A JP 2013528398A
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butanol
culture
yeast
gdcw
production
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JP2013528398A5 (https=
Inventor
ヴァサンタ・ナガラジャン
マイケル・ジー・ブラムッチ
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ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー
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Publication of JP2013528398A publication Critical patent/JP2013528398A/ja
Publication of JP2013528398A5 publication Critical patent/JP2013528398A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2013515512A 2010-06-17 2011-06-16 ブタノール産生用の酵母生産培養物 Abandoned JP2013528398A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35573310P 2010-06-17 2010-06-17
US61/355,733 2010-06-17
PCT/US2011/040697 WO2011159894A1 (en) 2010-06-17 2011-06-16 Yeast production culture for the production of butanol

Publications (2)

Publication Number Publication Date
JP2013528398A true JP2013528398A (ja) 2013-07-11
JP2013528398A5 JP2013528398A5 (https=) 2014-07-03

Family

ID=44627329

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013515512A Abandoned JP2013528398A (ja) 2010-06-17 2011-06-16 ブタノール産生用の酵母生産培養物

Country Status (12)

Country Link
US (1) US20120149080A1 (https=)
EP (1) EP2582786A1 (https=)
JP (1) JP2013528398A (https=)
KR (1) KR20130027551A (https=)
CN (1) CN103201376A (https=)
AU (1) AU2011268326B2 (https=)
BR (1) BR112012031847A2 (https=)
CA (1) CA2801576A1 (https=)
MX (1) MX2012014550A (https=)
NZ (1) NZ603546A (https=)
WO (1) WO2011159894A1 (https=)
ZA (1) ZA201208575B (https=)

Families Citing this family (29)

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US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
CN101680007A (zh) 2007-04-18 2010-03-24 纳幕尔杜邦公司 使用高活性酮醇酸还原异构酶来发酵生产异丁醇
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
NZ591126A (en) 2008-09-29 2012-08-31 Butamax Tm Advanced Biofuels INCREASED HETEROLOGOUS Fe-S ENZYME ACTIIVTY IN YEAST
NZ600509A (en) 2009-12-29 2014-08-29 Butamax Tm Advanced Biofuels Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
BR112012020589B8 (pt) 2010-02-17 2021-05-18 Butamax Tm Advanced Biofuels célula hospedeira recombinante de levedura, método para fabricar um produto, método para converter 2,3-diidroxiisovalerato em alfa-cetoisovalerato, método para aumentar a atividade específica de um polipeptídeo heterólogo, método para aumentar o fluxo em uma via biossintética e método para aumentar a atividade de uma proteína
CA2810244C (en) 2010-09-07 2020-10-06 Butamax(Tm) Advanced Biofuels Llc Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
US9206443B2 (en) 2011-03-14 2015-12-08 Easel Biotechnologies, Llc Microbial synthesis of aldehydes and corresponding alcohols
WO2012129555A2 (en) 2011-03-24 2012-09-27 Butamax (Tm) Advanced Biofuels Llc Host cells and methods for production of isobutanol
AU2012286640B2 (en) 2011-07-28 2016-09-01 Butamax Advanced Biofuels Llc Keto-isovalerate decarboxylase enzymes and methods of use thereof
ES2728279T3 (es) 2011-11-03 2019-10-23 Easel Biotechnologies Llc Producción microbiana de n-butiraldehído
EP2788096A2 (en) 2011-12-09 2014-10-15 Butamax Advanced Biofuels LLC Process to remove product alcohols from fermentation broth
JP2015503351A (ja) 2011-12-30 2015-02-02 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー ブタノール生産のための遺伝的スイッチ
CA2861613A1 (en) 2011-12-30 2013-07-04 Butamax Advanced Biofuels Llc Fermentative production of alcohols
CA2868153A1 (en) 2012-03-23 2013-09-26 Butamax Advanced Biofuels Llc Acetate supplemention of medium for butanologens
CN104619835B (zh) * 2012-05-11 2018-06-19 布特马斯先进生物燃料有限责任公司 酮醇酸还原异构酶及其使用方法
AU2013305714A1 (en) 2012-08-22 2015-02-05 Butamax Advanced Biofuels Llc Production of fermentation products
WO2014047421A1 (en) 2012-09-21 2014-03-27 Butamax(Tm) Advanced Biofuels Llc Production of renewable hydrocarbon compositions
CA2886157A1 (en) 2012-09-26 2014-04-03 Butamax Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
US9650624B2 (en) 2012-12-28 2017-05-16 Butamax Advanced Biofuels Llc DHAD variants for butanol production
AU2014244216A1 (en) 2013-03-14 2015-09-24 E.I. Du Pont De Nemours And Company Glycerol 3- phosphate dehydrogenase for butanol production
US9034631B2 (en) * 2013-03-14 2015-05-19 Poet Research, Inc. Systems and methods for yeast propagation
US9771602B2 (en) 2013-03-15 2017-09-26 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
WO2014151190A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Dhad variants and methods of screening
US9663759B2 (en) * 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
CA2957920A1 (en) 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same
CA2973776A1 (en) * 2015-02-10 2016-08-18 Erbsloh Geisenheim AG Method of producing yeast mutants and the use thereof
US11692207B2 (en) 2016-05-05 2023-07-04 Newpek S.A. De C.V. Enzymatic methods for butanol production

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
US4284724A (en) 1977-08-25 1981-08-18 Hideki Fukuda Method of highly concentrated cultivation of yeasts
US4414329A (en) 1980-01-15 1983-11-08 Phillips Petroleum Company Biochemical conversions by yeast fermentation at high cell densities
US4765992A (en) 1984-06-01 1988-08-23 Universite De Bordeaux Ii Stimulation of alcoholic fermentation by adsorption of toxic substances with cell walls
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
RU2394913C2 (ru) * 2005-10-26 2010-07-20 Е.И.Дюпон Де Немур Энд Компани Ферментативное получение четырехуглеродных спиртов
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
CN101680007A (zh) 2007-04-18 2010-03-24 纳幕尔杜邦公司 使用高活性酮醇酸还原异构酶来发酵生产异丁醇
WO2009046370A2 (en) 2007-10-04 2009-04-09 Bio Architecture Lab, Inc. Biofuel production
CN101918572A (zh) * 2007-10-26 2010-12-15 阿伯燃料公司 正丁醇的生产方法
WO2009085953A2 (en) 2007-12-20 2009-07-09 E. I. Du Pont De Nemours And Company Ketol-acid reductoisomerase using nadh
MY153731A (en) 2007-12-27 2015-03-13 Gevo Inc Recovery of higher alcohols from dilute aqueous solutions
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
NZ588988A (en) * 2008-06-04 2012-08-31 Butamax Tm Advanced Biofuels A method for producing butanol using two-phase extractive fermentation
BRPI0909989A2 (pt) 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
ES2521675T3 (es) 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas
BRPI0914521A2 (pt) 2008-10-27 2016-07-26 Butamax Advanced Biofuels Llc célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol
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IN2012DN02227A (https=) 2009-09-29 2015-08-21 Butamax Tm Advanced Biofuels
BR112012006939A2 (pt) 2009-09-29 2015-09-08 Butamax Tm Advanced Biofuels célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides

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Publication number Publication date
EP2582786A1 (en) 2013-04-24
BR112012031847A2 (pt) 2016-02-16
WO2011159894A1 (en) 2011-12-22
CN103201376A (zh) 2013-07-10
CA2801576A1 (en) 2011-12-22
US20120149080A1 (en) 2012-06-14
MX2012014550A (es) 2013-01-29
AU2011268326A1 (en) 2012-12-06
AU2011268326B2 (en) 2015-02-05
ZA201208575B (en) 2014-01-29
NZ603546A (en) 2014-10-31
KR20130027551A (ko) 2013-03-15

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