JP2013526705A - 神経変性疾患のリスクの推移を検出およびプロファイリングする方法 - Google Patents

神経変性疾患のリスクの推移を検出およびプロファイリングする方法 Download PDF

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JP2013526705A
JP2013526705A JP2013510115A JP2013510115A JP2013526705A JP 2013526705 A JP2013526705 A JP 2013526705A JP 2013510115 A JP2013510115 A JP 2013510115A JP 2013510115 A JP2013510115 A JP 2013510115A JP 2013526705 A JP2013526705 A JP 2013526705A
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stem cell
determining
neurodegenerative disease
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disease
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JP2013526705A5 (enExample
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シー. シェカー マヤニール,
俊介 伊地
タダノリ トミタ
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アン アンド ロバート エイチ. ルーリー チルドレンズ ホスピタル オブ シカゴ
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/12Post-translational modifications [PTMs] in chemical analysis of biological material alkylation, e.g. methylation, (iso-)prenylation, farnesylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2835Movement disorders, e.g. Parkinson, Huntington, Tourette
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
JP2013510115A 2010-05-11 2011-04-21 神経変性疾患のリスクの推移を検出およびプロファイリングする方法 Pending JP2013526705A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39532110P 2010-05-11 2010-05-11
US61/395,321 2010-05-11
PCT/US2011/033387 WO2011142952A1 (en) 2010-05-11 2011-04-21 Method of detecting and profiling progression of the risk of neurodegenerative diseases

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JP2013526705A true JP2013526705A (ja) 2013-06-24
JP2013526705A5 JP2013526705A5 (enExample) 2014-03-27

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JP2013510115A Pending JP2013526705A (ja) 2010-05-11 2011-04-21 神経変性疾患のリスクの推移を検出およびプロファイリングする方法

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US (1) US20130029998A1 (enExample)
EP (1) EP2569625A4 (enExample)
JP (1) JP2013526705A (enExample)
CA (1) CA2795438A1 (enExample)
WO (1) WO2011142952A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019521953A (ja) * 2016-04-20 2019-08-08 エアラン セル テクノロジーズ, インコーポレイテッド K180ジメチル化h1.0タンパク質に関連する組成物および方法
JP2021500893A (ja) * 2017-10-25 2021-01-14 エアラン セル テクノロジーズ, インコーポレイテッド H1.0k180me2抗体、その作製および使用の方法
US12138282B2 (en) 2015-06-03 2024-11-12 Aelan Cell Technologies, Inc. Treatment with an IL-2 based therapy

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10282875B2 (en) 2015-12-11 2019-05-07 International Business Machines Corporation Graph-based analysis for bio-signal event sensing
KR102573778B1 (ko) 2017-02-17 2023-08-31 브리스톨-마이어스 스큅 컴퍼니 알파-시뉴클레인에 대한 항체 및 그의 용도

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7025A (en) * 1850-01-15 Buckle
US11016A (en) * 1854-06-06 Method of turning hubs
WO2009058102A1 (en) * 2007-11-02 2009-05-07 Agency For Science, Technology And Research Methods and compounds for preventing and treating a tumour
WO2010001933A1 (ja) * 2008-07-01 2010-01-07 学校法人日本大学 標的遺伝子特異的ヒストン修飾制御剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050037992A1 (en) * 2003-07-22 2005-02-17 John Lyons Composition and method for treating neurological disorders

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7025A (en) * 1850-01-15 Buckle
US11016A (en) * 1854-06-06 Method of turning hubs
WO2009058102A1 (en) * 2007-11-02 2009-05-07 Agency For Science, Technology And Research Methods and compounds for preventing and treating a tumour
WO2010001933A1 (ja) * 2008-07-01 2010-01-07 学校法人日本大学 標的遺伝子特異的ヒストン修飾制御剤

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN5013008714; SEONG: 'HUNTINGTIN FACILITATES POLYCOMB REPRESSIVE COMPLEX 2' HUMAN MOLECULAR GENETICS V19 N4, 20100215, P573-583 *
JPN5013008715; SUBIRA: 'FLOW CYTOMETRIC ANALYSIS OF CEREBROSPINAL FLUID SAMPLES AND ITS USEFULNESS IN ROUTINE CLINICAL PRACT' AMERICAN JOURNAL OF CLINICAL PATHOLOGY V117 N6, 200206, P952-958, AMERICAN SOCIETY FOR CLINICAL PATHOLOGY *
JPN5013008718; MORICI: HUNTINGTON'S OUTREACH PROJECT FOR EDUCATION, AT STANFORD , 20050830 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12138282B2 (en) 2015-06-03 2024-11-12 Aelan Cell Technologies, Inc. Treatment with an IL-2 based therapy
JP2019521953A (ja) * 2016-04-20 2019-08-08 エアラン セル テクノロジーズ, インコーポレイテッド K180ジメチル化h1.0タンパク質に関連する組成物および方法
JP6994469B2 (ja) 2016-04-20 2022-02-04 エアラン セル テクノロジーズ, インコーポレイテッド K180ジメチル化h1.0タンパク質に関連する組成物および方法
JP2024016122A (ja) * 2016-04-20 2024-02-06 エアラン セル テクノロジーズ, インコーポレイテッド K180ジメチル化h1.0タンパク質に関連する組成物および方法
US12210018B2 (en) 2016-04-20 2025-01-28 Aelan Cell Technologies, Inc. Compositions and methods related to the methylation of histone H1.0 protein
JP2021500893A (ja) * 2017-10-25 2021-01-14 エアラン セル テクノロジーズ, インコーポレイテッド H1.0k180me2抗体、その作製および使用の方法
JP7252953B2 (ja) 2017-10-25 2023-04-05 エアラン セル テクノロジーズ, インコーポレイテッド H1.0k180me2抗体、その作製および使用の方法

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CA2795438A1 (en) 2011-11-17
US20130029998A1 (en) 2013-01-31
EP2569625A4 (en) 2013-12-04
EP2569625A1 (en) 2013-03-20
WO2011142952A1 (en) 2011-11-17

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