JP2013523682A5 - - Google Patents
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- Publication number
- JP2013523682A5 JP2013523682A5 JP2013501791A JP2013501791A JP2013523682A5 JP 2013523682 A5 JP2013523682 A5 JP 2013523682A5 JP 2013501791 A JP2013501791 A JP 2013501791A JP 2013501791 A JP2013501791 A JP 2013501791A JP 2013523682 A5 JP2013523682 A5 JP 2013523682A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- vaccine composition
- composition according
- alzheimer
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 21
- 229960005486 vaccine Drugs 0.000 claims 20
- 108090000765 processed proteins & peptides Proteins 0.000 claims 19
- 208000024827 Alzheimer disease Diseases 0.000 claims 10
- 206010012289 Dementia Diseases 0.000 claims 10
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 241001534160 Escherichia virus Qbeta Species 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 238000004220 aggregation Methods 0.000 claims 1
- 230000002776 aggregation Effects 0.000 claims 1
- 230000001430 anti-depressive effect Effects 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000000935 antidepressant agent Substances 0.000 claims 1
- 229940005513 antidepressants Drugs 0.000 claims 1
- 239000003472 antidiabetic agent Substances 0.000 claims 1
- 229940125708 antidiabetic agent Drugs 0.000 claims 1
- 239000003524 antilipemic agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 239000000164 antipsychotic agent Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- BUGYDGFZZOZRHP-UHFFFAOYSA-N memantine Chemical compound C1C(C2)CC3(C)CC1(C)CC2(N)C3 BUGYDGFZZOZRHP-UHFFFAOYSA-N 0.000 claims 1
- 229960004640 memantine Drugs 0.000 claims 1
- 239000002664 nootropic agent Substances 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10158273 | 2010-03-29 | ||
| EP10158273.2 | 2010-03-29 | ||
| US36169710P | 2010-07-06 | 2010-07-06 | |
| US61/361,697 | 2010-07-06 | ||
| PCT/EP2011/054735 WO2011120924A1 (en) | 2010-03-29 | 2011-03-28 | Composition comprising the amyloid beta 1-6 peptide coupled to a virus-like particle and an adjuvant |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016115660A Division JP2017008035A (ja) | 2010-03-29 | 2016-06-09 | ウイルス様粒子に結合しているアミロイドベータ１−６ペプチドおよびアジュバントを含む組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013523682A JP2013523682A (ja) | 2013-06-17 |
| JP2013523682A5 true JP2013523682A5 (https=) | 2014-05-01 |
| JP6088422B2 JP6088422B2 (ja) | 2017-03-01 |
Family
ID=42285305
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013501791A Expired - Fee Related JP6088422B2 (ja) | 2010-03-29 | 2011-03-28 | ウイルス様粒子に結合しているアミロイドベータ１−６ペプチドおよびアジュバントを含む組成物 |
| JP2016115660A Pending JP2017008035A (ja) | 2010-03-29 | 2016-06-09 | ウイルス様粒子に結合しているアミロイドベータ１−６ペプチドおよびアジュバントを含む組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016115660A Pending JP2017008035A (ja) | 2010-03-29 | 2016-06-09 | ウイルス様粒子に結合しているアミロイドベータ１−６ペプチドおよびアジュバントを含む組成物 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US20130011431A1 (https=) |
| EP (1) | EP2552489A1 (https=) |
| JP (2) | JP6088422B2 (https=) |
| KR (1) | KR20130018407A (https=) |
| CN (2) | CN104436212A (https=) |
| AR (1) | AR080810A1 (https=) |
| AU (1) | AU2011234656B2 (https=) |
| BR (1) | BR112012024708A2 (https=) |
| CA (1) | CA2793580A1 (https=) |
| CL (1) | CL2012002685A1 (https=) |
| CO (1) | CO6630127A2 (https=) |
| EC (1) | ECSP12012180A (https=) |
| GT (1) | GT201200265A (https=) |
| IL (1) | IL221540B (https=) |
| MA (1) | MA34084B1 (https=) |
| MX (1) | MX2012011340A (https=) |
| NZ (1) | NZ601729A (https=) |
| PE (1) | PE20130642A1 (https=) |
| PH (1) | PH12012501683A1 (https=) |
| RU (1) | RU2603486C2 (https=) |
| SG (2) | SG183806A1 (https=) |
| TN (1) | TN2012000431A1 (https=) |
| TW (2) | TW201618806A (https=) |
| WO (1) | WO2011120924A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3027205A4 (en) | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| WO2015165971A1 (en) * | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| PL3137094T3 (pl) * | 2014-04-29 | 2023-03-13 | Advantage Therapeutics, Inc. | Leczenie i profilaktyka choroby alzheimera (ad) |
| EP3137097B1 (en) * | 2014-04-29 | 2023-06-21 | ADvantage Therapeutics, Inc. | Treatment and prevention of alzheimer's disease (ad) |
| WO2015165961A1 (en) | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| EP3137093B1 (en) * | 2014-04-29 | 2017-09-13 | Affiris AG | Treatment and prevention of alzheimer's disease (ad) |
| ES2571055B1 (es) * | 2016-02-15 | 2016-12-28 | Araclon Biotech, S.L. | Conjugado amiloide y usos y procedimientos del mismo |
| US12233177B2 (en) | 2019-09-16 | 2025-02-25 | Amgen Inc. | Method for external sterilization of drug delivery device |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU201906B (en) | 1987-03-04 | 1991-01-28 | Sandoz Ag | Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them |
| US6153201A (en) * | 1993-03-09 | 2000-11-28 | University Of Rochester | Oral immunization with papillomavirus virus-like particles |
| FR2734484B1 (fr) * | 1995-05-24 | 1997-06-27 | Pasteur Merieux Serums Vacc | Composition vaccinale liquide et procede de fabrication |
| EP1006999A2 (en) * | 1997-07-08 | 2000-06-14 | Chiron Corporation | Use of submicron oil-in-water emulsions with dna vaccines |
| CA2452720C (en) * | 2001-07-26 | 2012-04-17 | Chiron S.R.L. | Vaccines comprising aluminium adjuvants and histidine |
| SI1524994T1 (sl) * | 2002-07-19 | 2011-08-31 | Cytos Biotechnology Ag | Sestavki cepiv, ki vsebujejo amiloidne beta 1-6 antigenske mreĹľe |
| CN100409896C (zh) * | 2003-03-31 | 2008-08-13 | 姚志彬 | 一种老年性痴呆疫苗及其制备方法 |
| CA2580208A1 (en) * | 2004-09-21 | 2006-03-30 | Cytos Biotechnology Ag | Virus-like particles comprising a fusion protein of the coat protein of ap205 and an antigenic polypeptide |
| GB0424563D0 (en) * | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
| CN101318015A (zh) * | 2008-06-25 | 2008-12-10 | 中山大学 | 老年性痴呆重组蛋白疫苗及其制备方法 |
-
2011
- 2011-03-28 BR BR112012024708A patent/BR112012024708A2/pt not_active Application Discontinuation
- 2011-03-28 CN CN201410789825.6A patent/CN104436212A/zh active Pending
- 2011-03-28 KR KR1020127025613A patent/KR20130018407A/ko not_active Ceased
- 2011-03-28 PE PE2012001825A patent/PE20130642A1/es not_active Application Discontinuation
- 2011-03-28 MA MA35241A patent/MA34084B1/fr unknown
- 2011-03-28 EP EP11711322A patent/EP2552489A1/en not_active Withdrawn
- 2011-03-28 SG SG2012060554A patent/SG183806A1/en unknown
- 2011-03-28 CN CN2011800162176A patent/CN102834118A/zh active Pending
- 2011-03-28 PH PH1/2012/501683A patent/PH12012501683A1/en unknown
- 2011-03-28 CA CA2793580A patent/CA2793580A1/en not_active Abandoned
- 2011-03-28 TW TW104125184A patent/TW201618806A/zh unknown
- 2011-03-28 RU RU2012145734/15A patent/RU2603486C2/ru not_active IP Right Cessation
- 2011-03-28 US US13/578,017 patent/US20130011431A1/en not_active Abandoned
- 2011-03-28 TW TW100110650A patent/TW201138805A/zh unknown
- 2011-03-28 SG SG10201505374TA patent/SG10201505374TA/en unknown
- 2011-03-28 MX MX2012011340A patent/MX2012011340A/es active IP Right Grant
- 2011-03-28 NZ NZ601729A patent/NZ601729A/xx not_active IP Right Cessation
- 2011-03-28 JP JP2013501791A patent/JP6088422B2/ja not_active Expired - Fee Related
- 2011-03-28 AR ARP110101001A patent/AR080810A1/es not_active Application Discontinuation
- 2011-03-28 AU AU2011234656A patent/AU2011234656B2/en not_active Ceased
- 2011-03-28 WO PCT/EP2011/054735 patent/WO2011120924A1/en not_active Ceased
-
2012
- 2012-08-20 IL IL221540A patent/IL221540B/en not_active IP Right Cessation
- 2012-08-30 TN TNP2012000431A patent/TN2012000431A1/en unknown
- 2012-09-25 EC ECSP12012180 patent/ECSP12012180A/es unknown
- 2012-09-26 GT GT201200265A patent/GT201200265A/es unknown
- 2012-09-27 CL CL2012002685A patent/CL2012002685A1/es unknown
- 2012-10-01 CO CO12171902A patent/CO6630127A2/es unknown
-
2014
- 2014-08-11 US US14/456,562 patent/US20140348871A1/en not_active Abandoned
-
2015
- 2015-06-26 US US14/751,492 patent/US20150297692A1/en not_active Abandoned
- 2015-12-17 US US14/972,187 patent/US20160101167A1/en not_active Abandoned
-
2016
- 2016-06-09 JP JP2016115660A patent/JP2017008035A/ja active Pending
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