JP2013521058A5 - - Google Patents
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- Publication number
- JP2013521058A5 JP2013521058A5 JP2012556176A JP2012556176A JP2013521058A5 JP 2013521058 A5 JP2013521058 A5 JP 2013521058A5 JP 2012556176 A JP2012556176 A JP 2012556176A JP 2012556176 A JP2012556176 A JP 2012556176A JP 2013521058 A5 JP2013521058 A5 JP 2013521058A5
- Authority
- JP
- Japan
- Prior art keywords
- potential
- epidermal tissue
- electrode
- tissue
- voltage generator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001519 tissue Anatomy 0.000 claims 13
- 238000004520 electroporation Methods 0.000 claims 3
- 230000000451 tissue damage Effects 0.000 claims 2
- 231100000827 tissue damage Toxicity 0.000 claims 2
- 230000000007 visual effect Effects 0.000 claims 2
- 210000000434 stratum corneum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30942210P | 2010-03-01 | 2010-03-01 | |
| US61/309,422 | 2010-03-01 | ||
| PCT/US2011/026701 WO2011109406A1 (en) | 2010-03-01 | 2011-03-01 | A tolerable and minimally invasive skin electroporation device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013521058A JP2013521058A (ja) | 2013-06-10 |
| JP2013521058A5 true JP2013521058A5 (cg-RX-API-DMAC7.html) | 2014-04-17 |
| JP5706451B2 JP5706451B2 (ja) | 2015-04-22 |
Family
ID=44542539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556176A Active JP5706451B2 (ja) | 2010-03-01 | 2011-03-01 | 耐容性で最小侵襲性の皮膚電気穿孔装置 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11565107B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2542300B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5706451B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101872408B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102905755B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011223753B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012021805A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2789736A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2542300T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA025705B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2594498T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2012009986A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2542300T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2542300T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011109406A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102081868B1 (ko) * | 2011-06-28 | 2020-02-26 | 이노비오 파마수티컬즈, 인크. | 최소 침습 피부 전기천공 장치 |
| AU2015203882C1 (en) * | 2011-06-28 | 2017-09-21 | Inovio Pharmaceuticals, Inc. | A minimally invasive dermal electroporation device |
| US11013917B2 (en) | 2013-06-21 | 2021-05-25 | Newsouth Innovations Pty Limited | Method and apparatus for close-field electroporation |
| CN104689478A (zh) * | 2013-12-09 | 2015-06-10 | 深圳市瑞吉思科技有限公司 | 细胞再生仪 |
| CN103861202B (zh) * | 2014-03-18 | 2016-06-01 | 苏州壹达生物科技有限公司 | 一种利用空心电极针电穿孔给药的装置 |
| ES2807439T3 (es) * | 2015-03-31 | 2021-02-23 | Oncosec Medical Inc | Sistemas para electroporación mejorada basada en la detección de tejidos |
| AU2016381186B2 (en) | 2015-12-30 | 2022-01-20 | Inovio Pharmaceuticals, Inc. | Electroporation device with detachable needle array with lock-out system |
| WO2018064463A1 (en) * | 2016-09-30 | 2018-04-05 | University Of Florida Research Foundation, Inc. | Systems and methods including porous membrane for low-voltage continuous cell electroporation |
| CN107890608A (zh) * | 2017-12-01 | 2018-04-10 | 王嘉浩 | 淋巴细胞增升仪 |
| EP3880295B1 (en) * | 2019-02-04 | 2023-07-12 | Rutgers, the State University of New Jersey | Device for tissue electrotransfer using a microelectrode |
| US11071860B2 (en) | 2019-02-06 | 2021-07-27 | Oncosec Medical Incorporated | Systems and methods for detecting fault conditions in electroporation therapy |
| BR102019013578A2 (pt) * | 2019-06-28 | 2021-01-05 | Eqt Equipamentos E Tecnologia Ltda. | Ponta aplicadora de eletroporação para procedimento de eletroquimioterapia |
| KR102576604B1 (ko) | 2021-02-16 | 2023-09-08 | 주식회사 밀알 | 의료용 정밀 약물주입 및 전기천공 융합 전극 |
| KR20220159203A (ko) | 2021-05-25 | 2022-12-02 | 주식회사 밀알 | 의료용 정밀 약물주입 및 전기천공 융합 전극 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3994287A (en) * | 1974-07-01 | 1976-11-30 | Centre De Recherche Industrielle Du Quebec | Trocar |
| US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
| US6277116B1 (en) * | 1994-05-06 | 2001-08-21 | Vidaderm | Systems and methods for shrinking collagen in the dermis |
| ATE241405T1 (de) * | 1996-07-03 | 2003-06-15 | Altea Therapeutics Corp | Mehrfache mechanische mikroperforierung von haut oder schleimhäuten |
| US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
| NZ337853A (en) | 1997-04-03 | 2002-03-28 | Electrofect As | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
| WO1999001158A1 (fr) | 1997-06-30 | 1999-01-14 | Rhone-Poulenc Rorer S.A. | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
| US6241701B1 (en) * | 1997-08-01 | 2001-06-05 | Genetronics, Inc. | Apparatus for electroporation mediated delivery of drugs and genes |
| TW368420B (en) | 1997-11-04 | 1999-09-01 | Genetronics Inc | Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum |
| US7922709B2 (en) * | 1998-07-13 | 2011-04-12 | Genetronics, Inc. | Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation |
| EP1163024B1 (en) | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Delivery of macromolecules into cells |
| US6678558B1 (en) * | 1999-03-25 | 2004-01-13 | Genetronics, Inc. | Method and apparatus for reducing electroporation-mediated muscle reaction and pain response |
| US7113821B1 (en) * | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
| US20070016268A1 (en) | 2000-01-07 | 2007-01-18 | John Carter | Percutaneous electrode array |
| US7245963B2 (en) * | 2002-03-07 | 2007-07-17 | Advisys, Inc. | Electrode assembly for constant-current electroporation and use |
| US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
| EP1499255B1 (en) * | 2002-04-19 | 2015-07-22 | Syneron Medical Ltd. | Handheld transdermal drug delivery and analyte extraction |
| US20060036210A1 (en) | 2004-06-30 | 2006-02-16 | Lei Zhang | Modular electroporation device with disposable electrode and drug delivery components |
| US20100168501A1 (en) * | 2006-10-02 | 2010-07-01 | Daniel Rogers Burnett | Method and apparatus for magnetic induction therapy |
| CA3063263C (en) * | 2006-02-11 | 2024-01-16 | Genetronics, Inc. | Device and method for single-needle in vivo electroporation |
| CN101563132A (zh) * | 2006-10-17 | 2009-10-21 | Vgx药品公司 | 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法 |
| US20080287866A1 (en) * | 2007-01-31 | 2008-11-20 | Adam Heller | Methods and compositions for the treatment of pain |
-
2011
- 2011-03-01 KR KR1020127025208A patent/KR101872408B1/ko active Active
- 2011-03-01 DK DK11751208.7T patent/DK2542300T3/en active
- 2011-03-01 MX MX2012009986A patent/MX2012009986A/es active IP Right Grant
- 2011-03-01 AU AU2011223753A patent/AU2011223753B2/en active Active
- 2011-03-01 EP EP11751208.7A patent/EP2542300B1/en active Active
- 2011-03-01 WO PCT/US2011/026701 patent/WO2011109406A1/en not_active Ceased
- 2011-03-01 JP JP2012556176A patent/JP5706451B2/ja active Active
- 2011-03-01 PT PT117512087T patent/PT2542300T/pt unknown
- 2011-03-01 EA EA201201203A patent/EA025705B1/ru not_active IP Right Cessation
- 2011-03-01 CN CN201180011473.6A patent/CN102905755B/zh active Active
- 2011-03-01 US US13/581,702 patent/US11565107B2/en active Active
- 2011-03-01 ES ES11751208.7T patent/ES2594498T3/es active Active
- 2011-03-01 PL PL11751208T patent/PL2542300T3/pl unknown
- 2011-03-01 CA CA2789736A patent/CA2789736A1/en active Pending
- 2011-03-01 BR BR112012021805A patent/BR112012021805A2/pt active IP Right Grant
-
2022
- 2022-07-25 US US17/814,703 patent/US12491361B2/en active Active
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