JP2013518280A5 - - Google Patents
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- Publication number
- JP2013518280A5 JP2013518280A5 JP2012551128A JP2012551128A JP2013518280A5 JP 2013518280 A5 JP2013518280 A5 JP 2013518280A5 JP 2012551128 A JP2012551128 A JP 2012551128A JP 2012551128 A JP2012551128 A JP 2012551128A JP 2013518280 A5 JP2013518280 A5 JP 2013518280A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- kinetic parameters
- sensing surface
- biosensor
- speed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 16
- 229920000642 polymer Polymers 0.000 claims 8
- 239000012530 fluid Substances 0.000 claims 5
- 238000010494 dissociation reaction Methods 0.000 claims 3
- 230000005593 dissociations Effects 0.000 claims 3
- 239000003446 ligand Substances 0.000 claims 3
- 229920002521 macromolecule Polymers 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000027455 binding Effects 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 238000012482 interaction analysis Methods 0.000 claims 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 2
- 230000002776 aggregation Effects 0.000 claims 1
- 238000004220 aggregation Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1050093 | 2010-01-29 | ||
| SE1050093-2 | 2010-01-29 | ||
| PCT/SE2011/050087 WO2011093782A1 (en) | 2010-01-29 | 2011-01-27 | Method for determination of aggregates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013518280A JP2013518280A (ja) | 2013-05-20 |
| JP2013518280A5 true JP2013518280A5 (enExample) | 2014-03-13 |
| JP5873810B2 JP5873810B2 (ja) | 2016-03-01 |
Family
ID=44319583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012551128A Active JP5873810B2 (ja) | 2010-01-29 | 2011-01-27 | 凝集体決定法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9470683B2 (enExample) |
| EP (1) | EP2529234B1 (enExample) |
| JP (1) | JP5873810B2 (enExample) |
| WO (1) | WO2011093782A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10458984B2 (en) | 2014-01-29 | 2019-10-29 | Ge Healthcare Bio-Sciences Ab | Method and system for interaction analysis |
| GB201720162D0 (en) | 2017-12-04 | 2018-01-17 | Univ Oxford Innovation Ltd | Method |
| CN113196055B (zh) | 2018-10-15 | 2025-06-27 | 马克斯·普朗克科学促进协会 | 用于治疗疾病的化合物及其筛选方法 |
| US20220074927A1 (en) * | 2019-02-05 | 2022-03-10 | Solve Research And Consultancy Ab | A Label-Free Detection Method for Characterization of the Behavior of a Component in a Liquid |
| JP7564110B2 (ja) | 2019-02-08 | 2024-10-08 | デューポイント セラピューティクス， インコーポレイテッド | 化合物の凝縮物に関連する特性を特性評価する方法およびその使用 |
| CN114729941A (zh) | 2019-09-18 | 2022-07-08 | 露点治疗公司 | 筛选凝聚物相关特异性的方法及其用途 |
| GB201917630D0 (en) * | 2019-12-03 | 2020-01-15 | Ge Healthcare Bio Sciences Ab | Method for determination of aggregates |
| WO2022270606A1 (ja) * | 2021-06-25 | 2022-12-29 | コニカミノルタ株式会社 | 解析システム、学習済みモデル生成装置および判別システムならびに解析方法、学習済みモデル生成方法および判別方法 |
| WO2022270043A1 (ja) * | 2021-06-25 | 2022-12-29 | コニカミノルタ株式会社 | 解析システム、学習済みモデル生成装置および判別システムならびに解析方法、学習済みモデル生成方法および判別方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9503028D0 (sv) * | 1995-09-01 | 1995-09-01 | Pharmacia Biosensor Ab | Method of analysing chemical and physical interactions at a sensor surface |
| GB0225491D0 (en) * | 2002-11-01 | 2002-12-11 | Farfield Sensors Ltd | Device |
| JP5596255B2 (ja) * | 2003-06-06 | 2014-09-24 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 分子相互作用パラメータの決定のための方法およびシステム |
| US7373255B2 (en) * | 2003-06-06 | 2008-05-13 | Biacore Ab | Method and system for determination of molecular interaction parameters |
| US20090288479A1 (en) * | 2003-11-17 | 2009-11-26 | Woody Shane C | Standing wave fluidic and biological tools |
| GB0705088D0 (en) | 2007-03-16 | 2007-04-25 | Akubio Ltd | Improvements in or relating to detection and/or characterisation of aggregates |
| AU2008296386A1 (en) * | 2007-08-28 | 2009-03-12 | Biogen Idec Ma Inc. | Compositions that bind multiple epitopes of IGF-1R |
| CN101874042B9 (zh) * | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| JP2009078946A (ja) | 2007-09-26 | 2009-04-16 | Fujifilm Corp | コア−シェル型金属酸化物粒子及びその製造方法 |
| EP2491391B1 (en) | 2009-10-23 | 2018-02-28 | GE Healthcare Bio-Sciences AB | Method for determination of macromolecular multimers |
-
2011
- 2011-01-27 WO PCT/SE2011/050087 patent/WO2011093782A1/en not_active Ceased
- 2011-01-27 US US13/575,197 patent/US9470683B2/en active Active
- 2011-01-27 JP JP2012551128A patent/JP5873810B2/ja active Active
- 2011-01-27 EP EP11737368.8A patent/EP2529234B1/en active Active
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