JP5873810B2 - 凝集体決定法 - Google Patents

凝集体決定法 Download PDF

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Publication number
JP5873810B2
JP5873810B2 JP2012551128A JP2012551128A JP5873810B2 JP 5873810 B2 JP5873810 B2 JP 5873810B2 JP 2012551128 A JP2012551128 A JP 2012551128A JP 2012551128 A JP2012551128 A JP 2012551128A JP 5873810 B2 JP5873810 B2 JP 5873810B2
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JP
Japan
Prior art keywords
polymer
aggregates
binding
kinetic parameters
monomer
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JP2012551128A
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English (en)
Japanese (ja)
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JP2013518280A (ja
JP2013518280A5 (enExample
Inventor
ローファス,ステファン
パーソン,ビヨーン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Sweden AB
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Amersham Bioscience AB
GE Healthcare Bio Sciences Corp
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Application filed by Amersham Bioscience AB, GE Healthcare Bio Sciences Corp filed Critical Amersham Bioscience AB
Publication of JP2013518280A publication Critical patent/JP2013518280A/ja
Publication of JP2013518280A5 publication Critical patent/JP2013518280A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2012551128A 2010-01-29 2011-01-27 凝集体決定法 Active JP5873810B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1050093 2010-01-29
SE1050093-2 2010-01-29
PCT/SE2011/050087 WO2011093782A1 (en) 2010-01-29 2011-01-27 Method for determination of aggregates

Publications (3)

Publication Number Publication Date
JP2013518280A JP2013518280A (ja) 2013-05-20
JP2013518280A5 JP2013518280A5 (enExample) 2014-03-13
JP5873810B2 true JP5873810B2 (ja) 2016-03-01

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ID=44319583

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012551128A Active JP5873810B2 (ja) 2010-01-29 2011-01-27 凝集体決定法

Country Status (4)

Country Link
US (1) US9470683B2 (enExample)
EP (1) EP2529234B1 (enExample)
JP (1) JP5873810B2 (enExample)
WO (1) WO2011093782A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106471372B (zh) * 2014-01-29 2019-10-11 通用电气健康护理生物科学股份公司 用于相互作用分析的方法和系统
GB201720162D0 (en) 2017-12-04 2018-01-17 Univ Oxford Innovation Ltd Method
CA3115315A1 (en) 2018-10-15 2020-04-23 Anthony A. HYMAN Compounds for treatment of diseases and methods of screening therefor
EP3921836A1 (en) * 2019-02-05 2021-12-15 Solve Research and Consultancy AB A label-free detection method for characterization of the behavior of a component in a liquid
WO2020163795A1 (en) 2019-02-08 2020-08-13 Dewpoint Therapeutics, Inc. Methods of characterizing condensate-associated characteristics of compounds and uses thereof
CA3153010A1 (en) 2019-09-18 2021-03-25 Dewpoint Therapeutics, Inc. Methods of screening for condensate-associated specificity and uses thereof
GB201917630D0 (en) * 2019-12-03 2020-01-15 Ge Healthcare Bio Sciences Ab Method for determination of aggregates
WO2022270043A1 (ja) * 2021-06-25 2022-12-29 コニカミノルタ株式会社 解析システム、学習済みモデル生成装置および判別システムならびに解析方法、学習済みモデル生成方法および判別方法
WO2022270606A1 (ja) * 2021-06-25 2022-12-29 コニカミノルタ株式会社 解析システム、学習済みモデル生成装置および判別システムならびに解析方法、学習済みモデル生成方法および判別方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503028D0 (sv) * 1995-09-01 1995-09-01 Pharmacia Biosensor Ab Method of analysing chemical and physical interactions at a sensor surface
GB0225491D0 (en) * 2002-11-01 2002-12-11 Farfield Sensors Ltd Device
US7373255B2 (en) * 2003-06-06 2008-05-13 Biacore Ab Method and system for determination of molecular interaction parameters
AU2004245883B2 (en) * 2003-06-06 2009-09-24 Cytiva Sweden Ab Method and system for determination of molecular interaction parameters
US20090288479A1 (en) * 2003-11-17 2009-11-26 Woody Shane C Standing wave fluidic and biological tools
GB0705088D0 (en) * 2007-03-16 2007-04-25 Akubio Ltd Improvements in or relating to detection and/or characterisation of aggregates
CN101842116A (zh) * 2007-08-28 2010-09-22 比奥根艾迪克Ma公司 结合igf-1r多个表位的组合物
DK2202245T3 (en) * 2007-09-26 2016-11-21 Chugai Pharmaceutical Co Ltd A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR
JP2009078946A (ja) 2007-09-26 2009-04-16 Fujifilm Corp コア−シェル型金属酸化物粒子及びその製造方法
EP2491391B1 (en) 2009-10-23 2018-02-28 GE Healthcare Bio-Sciences AB Method for determination of macromolecular multimers

Also Published As

Publication number Publication date
WO2011093782A1 (en) 2011-08-04
EP2529234A1 (en) 2012-12-05
US9470683B2 (en) 2016-10-18
JP2013518280A (ja) 2013-05-20
EP2529234B1 (en) 2015-11-25
EP2529234A4 (en) 2013-07-03
US20120295369A1 (en) 2012-11-22

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