JP2013516490A5 - - Google Patents

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Publication number
JP2013516490A5
JP2013516490A5 JP2012548200A JP2012548200A JP2013516490A5 JP 2013516490 A5 JP2013516490 A5 JP 2013516490A5 JP 2012548200 A JP2012548200 A JP 2012548200A JP 2012548200 A JP2012548200 A JP 2012548200A JP 2013516490 A5 JP2013516490 A5 JP 2013516490A5
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JP
Japan
Prior art keywords
alkyl
alkylene
pharmaceutically acceptable
acceptable salt
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012548200A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013516490A (ja
JP5705239B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/020639 external-priority patent/WO2011085291A1/en
Publication of JP2013516490A publication Critical patent/JP2013516490A/ja
Publication of JP2013516490A5 publication Critical patent/JP2013516490A5/ja
Application granted granted Critical
Publication of JP5705239B2 publication Critical patent/JP5705239B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012548200A 2010-01-11 2011-01-10 セロトニンおよびノルエピネフリン再取込みインヒビターとしての１−（２−フェノキシメチルフェニル）ピペラジン化合物 Expired - Fee Related JP5705239B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29394910P 2010-01-11 2010-01-11
US61/293,949 2010-01-11
PCT/US2011/020639 WO2011085291A1 (en) 2010-01-11 2011-01-10 1 - (2 - phenoxymethylphenyl) piperazine compounds as serotonin and norepinephrine reuptake inhibitors

Publications (3)

Publication Number Publication Date
JP2013516490A JP2013516490A (ja) 2013-05-13
JP2013516490A5 true JP2013516490A5 (https=) 2013-12-19
JP5705239B2 JP5705239B2 (ja) 2015-04-22

Family

ID=43608270

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012548200A Expired - Fee Related JP5705239B2 (ja) 2010-01-11 2011-01-10 セロトニンおよびノルエピネフリン再取込みインヒビターとしての１−（２−フェノキシメチルフェニル）ピペラジン化合物

Country Status (4)

Country Link
US (2) US8778949B2 (https=)
EP (1) EP2523945A1 (https=)
JP (1) JP5705239B2 (https=)
WO (1) WO2011085291A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8304433B2 (en) 2008-11-14 2012-11-06 Theravance, Inc. Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
DE2549999A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Piperidin-derivate und verfahren zu ihrer herstellung
IL56369A (en) * 1978-01-20 1984-05-31 Erba Farmitalia Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
US4198417A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenoxyphenylpiperidines
EP0190496A3 (en) 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
US4956388A (en) * 1986-12-22 1990-09-11 Eli Lilly And Company 3-aryloxy-3-substituted propanamines
DE3835291A1 (de) * 1988-04-19 1989-11-02 Bayer Ag 1,3-disubstituierte pyrrolidine
GB9324018D0 (en) * 1993-11-23 1994-01-12 Merck Sharp & Dohme Therapeutic agents
US6518284B2 (en) * 1998-11-18 2003-02-11 Faes, Fabrica Espanola De Productos Quimicos Y Farmaceuticos S.A. 4-substituted piperidines
JP2000204040A (ja) * 1999-01-14 2000-07-25 Sankyo Co Ltd 精神神経症状の治療剤又は予防剤
US6630504B2 (en) * 2000-08-31 2003-10-07 Pfizer Inc. Phenoxyphenylheterocyclyl derivatives as SSRIs
US7294637B2 (en) * 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
WO2004017977A2 (en) * 2002-08-23 2004-03-04 Eli Lilly And Company 2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors
PT1635828E (pt) * 2003-04-04 2008-07-01 Lundbeck & Co As H Derivados de 4-(2-feniloxifenil) piperidina ou de 1,2,3,6-tetrahidropiridina como inibidores da recaptação da serotonina
SI1638933T1 (sl) * 2003-06-17 2008-10-31 Pfizer Derivati N-pirolidin-3-il-amida kot inhibitorji ponovnega privzema serotonina in noradrenalina
CA2553289A1 (en) * 2004-01-13 2005-07-28 Pfizer Inc. Piperazine derivatives which exhibit activity as serotonin and noradrenaline re-uptake inhibitors
SE0400234D0 (sv) * 2004-02-06 2004-02-06 Active Biotech Ab New compounds, methods for their preparation and use thereof
US20070072859A1 (en) * 2004-03-05 2007-03-29 Eli Lilly And Company Pharmaceutical compounds
BRPI0510453A (pt) * 2004-04-30 2007-10-30 Warner Lambert Co composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central
US20070142389A1 (en) * 2005-12-20 2007-06-21 Pfizer Inc. Piperidine derivatives
EP2066630A1 (en) 2006-08-23 2009-06-10 Pfizer Products Incorporated Piperidine derivatives
US8026257B2 (en) * 2007-07-11 2011-09-27 Bristol-Myers Squibb Company Substituted heterocyclic ethers and their use in CNS disorders
WO2009081259A1 (en) 2007-12-21 2009-07-02 Pfizer Inc. Phenoxy-pyridyl derivatives
MX2010013876A (es) * 2008-06-20 2011-03-04 Metabolex Inc Agonistas de arilo grpr119 y sus usos .
US8304433B2 (en) * 2008-11-14 2012-11-06 Theravance, Inc. Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound
WO2011119461A1 (en) * 2010-03-22 2011-09-29 Theravance, Inc. 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds

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