JP2013516425A5 - - Google Patents
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- Publication number
- JP2013516425A5 JP2013516425A5 JP2012547305A JP2012547305A JP2013516425A5 JP 2013516425 A5 JP2013516425 A5 JP 2013516425A5 JP 2012547305 A JP2012547305 A JP 2012547305A JP 2012547305 A JP2012547305 A JP 2012547305A JP 2013516425 A5 JP2013516425 A5 JP 2013516425A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- revascularization
- administration
- vascular occlusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 28
- 230000000250 revascularization Effects 0.000 claims 18
- 206010053648 Vascular occlusion Diseases 0.000 claims 7
- 208000021331 vascular occlusion disease Diseases 0.000 claims 7
- 206010047249 Venous thrombosis Diseases 0.000 claims 3
- 206010007559 Cardiac failure congestive Diseases 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 101800001904 NT-proBNP Proteins 0.000 claims 2
- 102400001263 NT-proBNP Human genes 0.000 claims 2
- 208000007536 Thrombosis Diseases 0.000 claims 2
- 239000003527 fibrinolytic agent Substances 0.000 claims 2
- 229960000103 thrombolytic agent Drugs 0.000 claims 2
- 206010051055 Deep vein thrombosis Diseases 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 208000000770 Non-ST Elevated Myocardial Infarction Diseases 0.000 claims 1
- 102000013566 Plasminogen Human genes 0.000 claims 1
- 108010051456 Plasminogen Proteins 0.000 claims 1
- 208000001647 Renal Insufficiency Diseases 0.000 claims 1
- 208000006117 ST-elevation myocardial infarction Diseases 0.000 claims 1
- 108010023197 Streptokinase Proteins 0.000 claims 1
- 108090000373 Tissue Plasminogen Activator Proteins 0.000 claims 1
- 102000003978 Tissue Plasminogen Activator Human genes 0.000 claims 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 claims 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000002411 adverse Effects 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 238000002399 angioplasty Methods 0.000 claims 1
- 230000007211 cardiovascular event Effects 0.000 claims 1
- 238000007887 coronary angioplasty Methods 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000002526 effect on cardiovascular system Effects 0.000 claims 1
- 230000003073 embolic effect Effects 0.000 claims 1
- 230000024924 glomerular filtration Effects 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 230000002440 hepatic effect Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000007917 intracranial administration Methods 0.000 claims 1
- 201000007272 intracranial sinus thrombosis Diseases 0.000 claims 1
- 201000006370 kidney failure Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 229940012957 plasmin Drugs 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 108010073863 saruplase Proteins 0.000 claims 1
- 229960005202 streptokinase Drugs 0.000 claims 1
- 108010008962 streptokinase-plasminogen complex Proteins 0.000 claims 1
- 229960000187 tissue plasminogen activator Drugs 0.000 claims 1
- 229960005356 urokinase Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29169909P | 2009-12-31 | 2009-12-31 | |
| US61/291,699 | 2009-12-31 | ||
| US36313810P | 2010-07-09 | 2010-07-09 | |
| US61/363,138 | 2010-07-09 | ||
| PCT/US2010/062538 WO2011082324A1 (en) | 2009-12-31 | 2010-12-30 | Methods for the prevention or treatment of vessel occlusion injury |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015104447A Division JP2015147810A (ja) | 2009-12-31 | 2015-05-22 | 血管閉塞傷害の予防または治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516425A JP2013516425A (ja) | 2013-05-13 |
| JP2013516425A5 true JP2013516425A5 (cg-RX-API-DMAC7.html) | 2014-02-20 |
Family
ID=44226816
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547305A Pending JP2013516425A (ja) | 2009-12-31 | 2010-12-30 | 血管閉塞傷害の予防または治療方法 |
| JP2015104447A Pending JP2015147810A (ja) | 2009-12-31 | 2015-05-22 | 血管閉塞傷害の予防または治療方法 |
| JP2016205764A Pending JP2017025093A (ja) | 2009-12-31 | 2016-10-20 | 血管閉塞傷害の予防または治療方法 |
| JP2018025914A Pending JP2018087225A (ja) | 2009-12-31 | 2018-02-16 | 血管閉塞傷害の予防または治療方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015104447A Pending JP2015147810A (ja) | 2009-12-31 | 2015-05-22 | 血管閉塞傷害の予防または治療方法 |
| JP2016205764A Pending JP2017025093A (ja) | 2009-12-31 | 2016-10-20 | 血管閉塞傷害の予防または治療方法 |
| JP2018025914A Pending JP2018087225A (ja) | 2009-12-31 | 2018-02-16 | 血管閉塞傷害の予防または治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (7) | US20130195837A1 (cg-RX-API-DMAC7.html) |
| EP (5) | EP2910250A1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP2013516425A (cg-RX-API-DMAC7.html) |
| CN (2) | CN102791280A (cg-RX-API-DMAC7.html) |
| AU (4) | AU2010339410A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2786280A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011082324A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2808029A3 (en) * | 2010-03-15 | 2015-04-01 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| CN103249423A (zh) * | 2010-07-09 | 2013-08-14 | 康肽德生物医药技术有限公司 | 预防或治疗缺血/再灌注损伤之后无复流的方法 |
| CN107496899A (zh) * | 2011-09-29 | 2017-12-22 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| CA2858550A1 (en) * | 2011-12-09 | 2013-06-13 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| CA2869080C (en) * | 2012-03-30 | 2020-09-01 | Stealth Peptides International, Inc. | Methods and compositions for the prevention and treatment neuropathy |
| EP4397314B1 (en) * | 2012-10-22 | 2025-12-03 | Stealth BioTherapeutics Inc. | Treatment of left ventricular remodeling |
| US10793597B2 (en) | 2013-03-01 | 2020-10-06 | Stealth Biotherapeutics Corp | Methods for the treatment of mitochondrial diseases associated with a mutation in SURF 1 or POLG gene resulting in a disruption of mitochondrial oxidative phosphorylation |
| EP3626252A1 (en) | 2013-03-01 | 2020-03-25 | Stealth Biotherapeutics Corp | Methods and compositions for the prevention or treatment of barth syndrome |
| EP3586864A1 (en) * | 2013-05-14 | 2020-01-01 | Stealth Biotherapeutics Corp | Methods for the prevention or treatment of left ventricle remodeling |
| US10047395B2 (en) | 2013-06-26 | 2018-08-14 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
| WO2015009414A1 (en) * | 2013-06-26 | 2015-01-22 | Stealth Peptides International, Inc. | Methods and compositions for regulating srca2a expression levels in myocardial infarction |
| WO2016004441A1 (en) * | 2014-07-03 | 2016-01-07 | Stealth Peptides International, Inc. | Methods for the prevention or treatment of acute myocardial infarction injury |
| US10744178B2 (en) | 2014-08-21 | 2020-08-18 | Stealth Biotherapeutics Corp | Methods and compositions for the prevention and treatment of disease |
| CA3010321A1 (en) * | 2015-12-31 | 2017-07-06 | Scott Duncan | Therapeutic compositions including peptides and uses thereof |
| WO2017156403A1 (en) * | 2016-03-11 | 2017-09-14 | Stealth Biotherapeutics | Crystalline salt forms |
| US11034724B2 (en) | 2017-04-05 | 2021-06-15 | Stealth Biotherapeutics Corp. | Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2 |
| IL305687B2 (en) * | 2017-12-15 | 2024-12-01 | Stealth Biotherapeutics Inc | Mitochondria-targeting peptides |
| US10676506B2 (en) | 2018-01-26 | 2020-06-09 | Stealth Biotherapeutics Corp. | Crystalline bis- and tris-hydrochloride salt of elamipretide |
| CN117243895A (zh) * | 2023-07-13 | 2023-12-19 | 河南大学 | 一种磷脂dspe-peg2000-ss31、负载药物的方法及其抗脑胶质瘤的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| SI2656854T1 (sl) * | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| CA3024434A1 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| EP3725324A1 (en) * | 2005-09-16 | 2020-10-21 | Cornell Research Foundation, Inc. | Aromatic-cationic peptide for use in a method for reducing cd36 expression |
| CN107802821A (zh) * | 2008-02-26 | 2018-03-16 | 康奈尔大学 | 用于防止和治疗急性肾损伤的方法 |
| EP2808029A3 (en) * | 2010-03-15 | 2015-04-01 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
-
2010
- 2010-12-30 US US13/519,780 patent/US20130195837A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062538 patent/WO2011082324A1/en not_active Ceased
- 2010-12-30 EP EP14197463.4A patent/EP2910250A1/en not_active Withdrawn
- 2010-12-30 EP EP10841732.0A patent/EP2519248A4/en not_active Withdrawn
- 2010-12-30 EP EP18183533.1A patent/EP3446698A1/en not_active Withdrawn
- 2010-12-30 CA CA2786280A patent/CA2786280A1/en not_active Abandoned
- 2010-12-30 EP EP16157727.5A patent/EP3090754A1/en not_active Withdrawn
- 2010-12-30 AU AU2010339410A patent/AU2010339410A1/en not_active Abandoned
- 2010-12-30 EP EP17169757.6A patent/EP3269380A1/en not_active Withdrawn
- 2010-12-30 JP JP2012547305A patent/JP2013516425A/ja active Pending
- 2010-12-30 CN CN201080065018XA patent/CN102791280A/zh active Pending
- 2010-12-30 CN CN201410010496.0A patent/CN103751763A/zh active Pending
-
2014
- 2014-01-07 US US14/149,606 patent/US20140341879A1/en not_active Abandoned
-
2015
- 2015-03-06 US US14/640,633 patent/US20160030501A1/en not_active Abandoned
- 2015-05-22 JP JP2015104447A patent/JP2015147810A/ja active Pending
- 2015-10-12 AU AU2015242952A patent/AU2015242952A1/en not_active Abandoned
-
2016
- 2016-05-26 US US15/165,139 patent/US20170100451A1/en not_active Abandoned
- 2016-10-20 JP JP2016205764A patent/JP2017025093A/ja active Pending
-
2017
- 2017-05-31 AU AU2017203662A patent/AU2017203662A1/en not_active Abandoned
- 2017-09-27 US US15/716,644 patent/US20180228864A1/en not_active Abandoned
-
2018
- 2018-02-16 JP JP2018025914A patent/JP2018087225A/ja active Pending
- 2018-12-05 US US16/211,125 patent/US20190336566A1/en not_active Abandoned
-
2019
- 2019-02-07 AU AU2019200823A patent/AU2019200823A1/en not_active Abandoned
-
2020
- 2020-02-28 US US16/804,900 patent/US20210023160A1/en not_active Abandoned
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