JP2013516425A - 血管閉塞傷害の予防または治療方法 - Google Patents

血管閉塞傷害の予防または治療方法 Download PDF

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JP2013516425A
JP2013516425A JP2012547305A JP2012547305A JP2013516425A JP 2013516425 A JP2013516425 A JP 2013516425A JP 2012547305 A JP2012547305 A JP 2012547305A JP 2012547305 A JP2012547305 A JP 2012547305A JP 2013516425 A JP2013516425 A JP 2013516425A
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peptide
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revascularization
administered
acid
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JP2013516425A5 (cg-RX-API-DMAC7.html
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ケニース ボロウ
ディー トラヴィス ウィルソン
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ステルス ペプチドズ インターナショナル インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2012547305A 2009-12-31 2010-12-30 血管閉塞傷害の予防または治療方法 Pending JP2013516425A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29169909P 2009-12-31 2009-12-31
US61/291,699 2009-12-31
US36313810P 2010-07-09 2010-07-09
US61/363,138 2010-07-09
PCT/US2010/062538 WO2011082324A1 (en) 2009-12-31 2010-12-30 Methods for the prevention or treatment of vessel occlusion injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015104447A Division JP2015147810A (ja) 2009-12-31 2015-05-22 血管閉塞傷害の予防または治療方法

Publications (2)

Publication Number Publication Date
JP2013516425A true JP2013516425A (ja) 2013-05-13
JP2013516425A5 JP2013516425A5 (cg-RX-API-DMAC7.html) 2014-02-20

Family

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012547305A Pending JP2013516425A (ja) 2009-12-31 2010-12-30 血管閉塞傷害の予防または治療方法
JP2015104447A Pending JP2015147810A (ja) 2009-12-31 2015-05-22 血管閉塞傷害の予防または治療方法
JP2016205764A Pending JP2017025093A (ja) 2009-12-31 2016-10-20 血管閉塞傷害の予防または治療方法
JP2018025914A Pending JP2018087225A (ja) 2009-12-31 2018-02-16 血管閉塞傷害の予防または治療方法

Family Applications After (3)

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JP2015104447A Pending JP2015147810A (ja) 2009-12-31 2015-05-22 血管閉塞傷害の予防または治療方法
JP2016205764A Pending JP2017025093A (ja) 2009-12-31 2016-10-20 血管閉塞傷害の予防または治療方法
JP2018025914A Pending JP2018087225A (ja) 2009-12-31 2018-02-16 血管閉塞傷害の予防または治療方法

Country Status (7)

Country Link
US (7) US20130195837A1 (cg-RX-API-DMAC7.html)
EP (5) EP2910250A1 (cg-RX-API-DMAC7.html)
JP (4) JP2013516425A (cg-RX-API-DMAC7.html)
CN (2) CN102791280A (cg-RX-API-DMAC7.html)
AU (4) AU2010339410A1 (cg-RX-API-DMAC7.html)
CA (1) CA2786280A1 (cg-RX-API-DMAC7.html)
WO (1) WO2011082324A1 (cg-RX-API-DMAC7.html)

Cited By (1)

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JP2021506823A (ja) * 2017-12-15 2021-02-22 ステルス バイオセラピューティクス コーポレーション ミトコンドリア標的化ペプチド

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EP2808029A3 (en) * 2010-03-15 2015-04-01 Stealth Peptides International, Inc. Combination therapies using cyclosporine and aromatic cationic peptides
CN103249423A (zh) * 2010-07-09 2013-08-14 康肽德生物医药技术有限公司 预防或治疗缺血/再灌注损伤之后无复流的方法
CN107496899A (zh) * 2011-09-29 2017-12-22 梅约医学教育与研究基金会 芳族阳离子肽和使用它们的方法
CA2858550A1 (en) * 2011-12-09 2013-06-13 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
CA2869080C (en) * 2012-03-30 2020-09-01 Stealth Peptides International, Inc. Methods and compositions for the prevention and treatment neuropathy
EP4397314B1 (en) * 2012-10-22 2025-12-03 Stealth BioTherapeutics Inc. Treatment of left ventricular remodeling
US10793597B2 (en) 2013-03-01 2020-10-06 Stealth Biotherapeutics Corp Methods for the treatment of mitochondrial diseases associated with a mutation in SURF 1 or POLG gene resulting in a disruption of mitochondrial oxidative phosphorylation
EP3626252A1 (en) 2013-03-01 2020-03-25 Stealth Biotherapeutics Corp Methods and compositions for the prevention or treatment of barth syndrome
EP3586864A1 (en) * 2013-05-14 2020-01-01 Stealth Biotherapeutics Corp Methods for the prevention or treatment of left ventricle remodeling
US10047395B2 (en) 2013-06-26 2018-08-14 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
WO2015009414A1 (en) * 2013-06-26 2015-01-22 Stealth Peptides International, Inc. Methods and compositions for regulating srca2a expression levels in myocardial infarction
WO2016004441A1 (en) * 2014-07-03 2016-01-07 Stealth Peptides International, Inc. Methods for the prevention or treatment of acute myocardial infarction injury
US10744178B2 (en) 2014-08-21 2020-08-18 Stealth Biotherapeutics Corp Methods and compositions for the prevention and treatment of disease
CA3010321A1 (en) * 2015-12-31 2017-07-06 Scott Duncan Therapeutic compositions including peptides and uses thereof
WO2017156403A1 (en) * 2016-03-11 2017-09-14 Stealth Biotherapeutics Crystalline salt forms
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
CN117243895A (zh) * 2023-07-13 2023-12-19 河南大学 一种磷脂dspe-peg2000-ss31、负载药物的方法及其抗脑胶质瘤的应用

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021506823A (ja) * 2017-12-15 2021-02-22 ステルス バイオセラピューティクス コーポレーション ミトコンドリア標的化ペプチド
JP7335880B2 (ja) 2017-12-15 2023-08-30 ステルス バイオセラピューティクス インコーポレイテッド ミトコンドリア標的化ペプチド
JP2023162279A (ja) * 2017-12-15 2023-11-08 ステルス バイオセラピューティクス インコーポレイテッド ミトコンドリア標的化ペプチド
JP7576670B2 (ja) 2017-12-15 2024-10-31 ステルス バイオセラピューティクス インコーポレイテッド ミトコンドリア標的化ペプチド

Also Published As

Publication number Publication date
EP3269380A1 (en) 2018-01-17
JP2015147810A (ja) 2015-08-20
CA2786280A1 (en) 2011-07-07
US20180228864A1 (en) 2018-08-16
AU2019200823A1 (en) 2019-02-28
EP3446698A1 (en) 2019-02-27
WO2011082324A1 (en) 2011-07-07
JP2018087225A (ja) 2018-06-07
AU2015242952A1 (en) 2015-10-29
CN102791280A (zh) 2012-11-21
JP2017025093A (ja) 2017-02-02
US20170100451A1 (en) 2017-04-13
EP2519248A4 (en) 2013-06-26
EP3090754A1 (en) 2016-11-09
US20130195837A1 (en) 2013-08-01
US20210023160A1 (en) 2021-01-28
AU2017203662A1 (en) 2017-06-15
EP2519248A1 (en) 2012-11-07
AU2010339410A1 (en) 2012-07-19
US20190336566A1 (en) 2019-11-07
CN103751763A (zh) 2014-04-30
EP2910250A1 (en) 2015-08-26
US20140341879A1 (en) 2014-11-20
US20160030501A1 (en) 2016-02-04

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