JP2013511958A - Imp−3オリゴペプチドおよびそれを含むワクチン - Google Patents

Imp−3オリゴペプチドおよびそれを含むワクチン Download PDF

Info

Publication number
JP2013511958A
JP2013511958A JP2012524961A JP2012524961A JP2013511958A JP 2013511958 A JP2013511958 A JP 2013511958A JP 2012524961 A JP2012524961 A JP 2012524961A JP 2012524961 A JP2012524961 A JP 2012524961A JP 2013511958 A JP2013511958 A JP 2013511958A
Authority
JP
Japan
Prior art keywords
hla
antigen
oligopeptide
imp
ctl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012524961A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013511958A5 (enExample
Inventor
泰治 西村
美智子 原尾
雄介 冨田
祐輔 中村
卓也 角田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncotherapy Science Inc
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of JP2013511958A publication Critical patent/JP2013511958A/ja
Publication of JP2013511958A5 publication Critical patent/JP2013511958A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/19Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5156Animal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/55Lung
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012524961A 2009-12-01 2010-11-30 Imp−3オリゴペプチドおよびそれを含むワクチン Pending JP2013511958A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26565709P 2009-12-01 2009-12-01
US61/265,657 2009-12-01
US37143410P 2010-08-06 2010-08-06
US61/371,434 2010-08-06
PCT/JP2010/006966 WO2011067920A1 (en) 2009-12-01 2010-11-30 Imp-3 oligopeptides and vaccines including the same

Publications (2)

Publication Number Publication Date
JP2013511958A true JP2013511958A (ja) 2013-04-11
JP2013511958A5 JP2013511958A5 (enExample) 2014-01-23

Family

ID=44114782

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012524961A Pending JP2013511958A (ja) 2009-12-01 2010-11-30 Imp−3オリゴペプチドおよびそれを含むワクチン

Country Status (14)

Country Link
US (1) US20120308590A1 (enExample)
EP (1) EP2507256A4 (enExample)
JP (1) JP2013511958A (enExample)
KR (1) KR20120099106A (enExample)
CN (1) CN102741271B (enExample)
AU (1) AU2010327878B2 (enExample)
BR (1) BR112012013139A2 (enExample)
CA (1) CA2782271A1 (enExample)
IL (1) IL219976A0 (enExample)
MX (1) MX2012006126A (enExample)
RU (1) RU2550695C2 (enExample)
SG (2) SG181107A1 (enExample)
TW (1) TW201124530A (enExample)
WO (1) WO2011067920A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016021506A1 (ja) * 2014-08-04 2016-02-11 オンコセラピー・サイエンス株式会社 Koc1由来ペプチドおよびそれを含むワクチン
JP2016525498A (ja) * 2013-05-24 2016-08-25 オンコセラピー・サイエンス株式会社 Th1細胞のIMP−3エピトープペプチドおよびこれを含有するワクチン
JP2019512242A (ja) * 2016-03-16 2019-05-16 イマティクス バイオテクノロジーズ ゲーエムベーハー がんに対する免疫療法で使用するための形質移入t細胞およびt細胞受容体
JP2019515653A (ja) * 2016-03-16 2019-06-13 イマティクス バイオテクノロジーズ ゲーエムベーハー がんに対する免疫療法で使用されるペプチドおよびペプチドの組み合わせ
US11730796B2 (en) 2016-03-16 2023-08-22 Immatics Biotechnologies Gmbh Transfected t-cells and t-cell receptors for use in immunotherapy against cancers

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140138900A (ko) 2012-03-09 2014-12-04 온코세라피 사이언스 가부시키가이샤 펩티드를 포함한 의약 조성물
GB201603568D0 (en) * 2016-03-01 2016-04-13 Immatics Biotechnologies Gmbh Efficient treatment options including peptides and combination of peptide and cell based medicaments for use in immunotherapy against urinary bladder cancer
HUE058717T2 (hu) 2017-01-25 2022-09-28 Ose Immunotherapeutics Eljárás egy stabil emulzió elõállítására peptid szállításához
EP3727434A1 (en) * 2017-12-23 2020-10-28 Rubius Therapeutics, Inc. Artificial antigen presenting cells and methods of use
CN114853847B (zh) 2022-06-29 2022-09-27 中国农业大学 辣椒籽分离的寡肽ftle及其在预防或治疗癌症中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002020036A1 (de) * 2000-09-06 2002-03-14 Mueller Friederike Arzneimittel mit einer für das rna-bindende koc-protein kodierenden dna-sequenz, einem koc-protein oder einer dna-sequenz des koc-promotors
JP2008510464A (ja) * 2004-08-19 2008-04-10 コリクサ コーポレイション 肺癌の治療および診断のための組成物および方法
JP2008530975A (ja) * 2005-02-25 2008-08-14 オンコセラピー・サイエンス株式会社 Ttk、urlc10、またはkoc1ポリペプチドを発現する肺癌に対するペプチドワクチン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10611818B2 (en) * 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
PL2172211T3 (pl) * 2008-10-01 2015-05-29 Immatics Biotechnologies Gmbh Kompozycja związanych z guzem peptydów i związana z tym szczepionka przeciwrakowa do leczenia glejaka (GBM) i innych rodzajów raka

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002020036A1 (de) * 2000-09-06 2002-03-14 Mueller Friederike Arzneimittel mit einer für das rna-bindende koc-protein kodierenden dna-sequenz, einem koc-protein oder einer dna-sequenz des koc-promotors
JP2008510464A (ja) * 2004-08-19 2008-04-10 コリクサ コーポレイション 肺癌の治療および診断のための組成物および方法
JP2008530975A (ja) * 2005-02-25 2008-08-14 オンコセラピー・サイエンス株式会社 Ttk、urlc10、またはkoc1ポリペプチドを発現する肺癌に対するペプチドワクチン

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6015007974; Cancer Sci. 98 (11), 2007, p.1803-1808 *
JPN7015000540; J. Immunol. 152, 1994, p.163-175 *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016525498A (ja) * 2013-05-24 2016-08-25 オンコセラピー・サイエンス株式会社 Th1細胞のIMP−3エピトープペプチドおよびこれを含有するワクチン
JP7070945B2 (ja) 2014-08-04 2022-05-18 オンコセラピー・サイエンス株式会社 Koc1由来ペプチドおよびそれを含むワクチン
JPWO2016021506A1 (ja) * 2014-08-04 2017-05-18 オンコセラピー・サイエンス株式会社 Koc1由来ペプチドおよびそれを含むワクチン
AU2015300256B2 (en) * 2014-08-04 2020-01-30 Oncotherapy Science, Inc. KOC1-Derived peptide and vaccine including same
US10576102B2 (en) 2014-08-04 2020-03-03 Oncotherapy Science, Inc. KOC1-derived peptide and vaccine including same
JP2020182487A (ja) * 2014-08-04 2020-11-12 オンコセラピー・サイエンス株式会社 Koc1由来ペプチドおよびそれを含むワクチン
IL280417A (en) * 2014-08-04 2021-03-01 Oncotherapy Science Inc A peptide derived from KOC1 and a vaccine containing it
WO2016021506A1 (ja) * 2014-08-04 2016-02-11 オンコセラピー・サイエンス株式会社 Koc1由来ペプチドおよびそれを含むワクチン
US11547723B2 (en) 2014-08-04 2023-01-10 Oncotherapy Science, Inc. KOC1-derived peptide and vaccine including same
JP2019512242A (ja) * 2016-03-16 2019-05-16 イマティクス バイオテクノロジーズ ゲーエムベーハー がんに対する免疫療法で使用するための形質移入t細胞およびt細胞受容体
JP2019515653A (ja) * 2016-03-16 2019-06-13 イマティクス バイオテクノロジーズ ゲーエムベーハー がんに対する免疫療法で使用されるペプチドおよびペプチドの組み合わせ
JP2022130472A (ja) * 2016-03-16 2022-09-06 イマティクス バイオテクノロジーズ ゲーエムベーハー がんに対する免疫療法で使用されるペプチドおよびペプチドの組み合わせ
US11730796B2 (en) 2016-03-16 2023-08-22 Immatics Biotechnologies Gmbh Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
US12466878B2 (en) 2016-03-16 2025-11-11 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers

Also Published As

Publication number Publication date
RU2012127358A (ru) 2014-01-10
RU2550695C2 (ru) 2015-05-10
SG181107A1 (en) 2012-07-30
US20120308590A1 (en) 2012-12-06
EP2507256A1 (en) 2012-10-10
SG10201407944TA (en) 2015-01-29
WO2011067920A1 (en) 2011-06-09
CN102741271B (zh) 2014-11-05
KR20120099106A (ko) 2012-09-06
AU2010327878B2 (en) 2014-11-20
AU2010327878A1 (en) 2012-06-21
IL219976A0 (en) 2012-07-31
BR112012013139A2 (pt) 2016-10-11
CN102741271A (zh) 2012-10-17
MX2012006126A (es) 2012-06-19
CA2782271A1 (en) 2011-06-09
EP2507256A4 (en) 2013-10-16
TW201124530A (en) 2011-07-16

Similar Documents

Publication Publication Date Title
JP5728717B2 (ja) Foxm1ペプチドおよびそれを含むワクチン
RU2550695C2 (ru) Олигопептиды imp-3 и содержащие их вакцины
JP5663790B2 (ja) Rab6kifl/kif20aエピトープペプチドおよびそれを含むワクチン
JP5728716B2 (ja) C1orf59ペプチドおよびそれを含むワクチン
US9745343B2 (en) Method of inducing an immune response by administering WDRPUH epitope peptides
WO2010070877A1 (en) Elovl7 epitope peptides and vaccines containing the same
AU2010216980B2 (en) FOXM1 peptides and vaccines containing the same
HK1240953A1 (en) Wdrpuh epitope peptides and vaccines containing the same
HK1165460B (en) Foxm1 peptides and vaccines containing the same
HK1165460A (en) Foxm1 peptides and vaccines containing the same

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131127

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131127

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150302

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20150317

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150706