JP2013510159A5 - - Google Patents

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Publication number
JP2013510159A5
JP2013510159A5 JP2012537955A JP2012537955A JP2013510159A5 JP 2013510159 A5 JP2013510159 A5 JP 2013510159A5 JP 2012537955 A JP2012537955 A JP 2012537955A JP 2012537955 A JP2012537955 A JP 2012537955A JP 2013510159 A5 JP2013510159 A5 JP 2013510159A5
Authority
JP
Japan
Prior art keywords
compound
difluoro
formula
fluoropyridine
pyridin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012537955A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013510159A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/055176 external-priority patent/WO2011056806A1/en
Publication of JP2013510159A publication Critical patent/JP2013510159A/ja
Publication of JP2013510159A5 publication Critical patent/JP2013510159A5/ja
Pending legal-status Critical Current

Links

JP2012537955A 2009-11-03 2010-11-02 ピラジノントロンビン阻害剤およびその中間体の製造方法 Pending JP2013510159A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2663CH2009 2009-11-03
IN2663/CHE/2009 2009-11-03
PCT/US2010/055176 WO2011056806A1 (en) 2009-11-03 2010-11-02 Process for the preparation of pyrazinone thrombin inhibitor and its intermediates

Publications (2)

Publication Number Publication Date
JP2013510159A JP2013510159A (ja) 2013-03-21
JP2013510159A5 true JP2013510159A5 (https=) 2013-12-19

Family

ID=43926105

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012537955A Pending JP2013510159A (ja) 2009-11-03 2010-11-02 ピラジノントロンビン阻害剤およびその中間体の製造方法

Country Status (10)

Country Link
US (1) US8541580B2 (https=)
EP (1) EP2496087A4 (https=)
JP (1) JP2013510159A (https=)
KR (1) KR20120106727A (https=)
CN (1) CN102711481A (https=)
AU (1) AU2010315338A1 (https=)
CA (1) CA2778922A1 (https=)
MX (1) MX2012005165A (https=)
RU (1) RU2012118499A (https=)
WO (1) WO2011056806A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140090663A (ko) 2011-11-07 2014-07-17 디아크론 파마슈티칼스, 인코포레이티드 직접 트롬빈 억제제의 연장 방출성 제형
MX392191B (es) 2015-10-26 2025-03-21 Bayer Cropscience Ag Derivados de heterociclos biciclicos condensados como agentes de control de plagas.
JP7535532B2 (ja) 2019-02-26 2024-08-16 バイエル・アクチエンゲゼルシヤフト 有害生物防除剤としての縮合二環式複素環式誘導体
EP3931193A1 (en) 2019-02-26 2022-01-05 Bayer Aktiengesellschaft Fused bicyclic heterocycle derivatives as pesticides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147078A (en) * 1998-05-19 2000-11-14 Merck & Co., Inc. Pyrazinone thrombin inhibitors
UA58636C2 (uk) * 1999-06-04 2003-08-15 Мерк Енд Ко., Інк. Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
EP1341784A2 (en) * 2000-12-06 2003-09-10 Merck & Co., Inc. Process for making a thrombin inhibitor
EP1422221A1 (en) * 2002-11-20 2004-05-26 Bayer CropScience SA Novel process for the preparation of 2-aminomethylpyridine derivative

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