JP2013506836A - プロテインキナーゼｃｋ２介在性疾患のｃｋ２阻害剤に対する感受性および反応を予測するバイオマーカー - Google Patents

プロテインキナーゼｃｋ２介在性疾患のｃｋ２阻害剤に対する感受性および反応を予測するバイオマーカー Download PDF

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JP2013506836A
JP2013506836A JP2012532136A JP2012532136A JP2013506836A JP 2013506836 A JP2013506836 A JP 2013506836A JP 2012532136 A JP2012532136 A JP 2012532136A JP 2012532136 A JP2012532136 A JP 2012532136A JP 2013506836 A JP2013506836 A JP 2013506836A
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polypeptide
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inhibitor
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デニス ドライジン
ショーン オブライエン
ケナ アンデレス
ダニエル ディー． フォンホフ
ジョン ケイ． シー． リム
クレア エス． パジェット
ジョシュア アール． ブリーサス
キャロライン ビー． ホ
ウィリアム ジー． ライス
アダム シディキ−ジェイン
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サイリーン ファーマシューティカルズ インコーポレーティッド
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
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    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
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  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2012532136A 2009-10-02 2010-10-04 プロテインキナーゼｃｋ２介在性疾患のｃｋ２阻害剤に対する感受性および反応を予測するバイオマーカー Pending JP2013506836A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US24827009P 2009-10-02 2009-10-02
US61/248,270 2009-10-02
US25580509P 2009-10-28 2009-10-28
US61/255,805 2009-10-28
US32377110P 2010-04-13 2010-04-13
US61/323,771 2010-04-13
US38068510P 2010-09-07 2010-09-07
US61/380,685 2010-09-07
PCT/US2010/051341 WO2011041785A1 (en) 2009-10-02 2010-10-04 Biomarkers for predicting the sensitivity and response of protein kinase ck2-mediated diseases to ck2 inhibitors

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JP2013506836A true JP2013506836A (ja) 2013-02-28

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JP2012532136A Pending JP2013506836A (ja) 2009-10-02 2010-10-04 プロテインキナーゼｃｋ２介在性疾患のｃｋ２阻害剤に対する感受性および反応を予測するバイオマーカー

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US (1) US20110212845A1 (https=)
EP (1) EP2483686A1 (https=)
JP (1) JP2013506836A (https=)
KR (1) KR20120104196A (https=)
AU (1) AU2010300307A1 (https=)
BR (1) BR112012007555B1 (https=)
CA (1) CA2776278A1 (https=)
IL (1) IL218935A0 (https=)
IN (1) IN2012DN03817A (https=)
MX (1) MX2012003997A (https=)
WO (1) WO2011041785A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150127611A (ko) * 2013-03-11 2015-11-17 노파르티스 아게 Wnt 억제제와 연관된 마커
JP2017507146A (ja) * 2014-02-18 2017-03-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Ｎｒｐ−１／ｏｂｒ複合体シグナル伝達経路により媒介される疾患の処置のための方法及び医薬組成物
JP2017524127A (ja) * 2014-07-18 2017-08-24 サノフイ 癌に罹患していることが疑われる患者のアフリベルセプトを用いた処置の結果を予測するための方法
WO2023190820A1 (ja) * 2022-03-30 2023-10-05 公立大学法人福島県立医科大学 抗ＣＫ２α抗体又はその断片
JP2024508547A (ja) * 2021-03-01 2024-02-27 ケンブリッジ・エンタープライズ・リミテッド ベンゾ［ｃ］［２，６］ナフチリジン誘導体、組成物およびその治療的使用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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GB201212773D0 (en) * 2012-07-18 2012-08-29 Ucl Business Plc Vascular remodelling
US9146545B2 (en) 2012-11-27 2015-09-29 Honeywell International Inc. Multivariable control system for setpoint design
WO2015053452A1 (ko) * 2013-10-08 2015-04-16 한국생명공학연구원 Ｃｘ－４９４５를 유효성분으로 함유하는 스플라이싱 조절제
KR101593595B1 (ko) * 2013-10-08 2016-02-12 한국생명공학연구원 Ｃｘ－４９４５를 유효성분으로 함유하는 스플라이싱 조절제
WO2016133860A1 (en) * 2015-02-16 2016-08-25 Board Of Regents Of The University Of Nebraska Cancer biomarkers and methods of use thereof
CN115160341B (zh) * 2022-07-18 2023-07-18 中国医学科学院医学实验动物研究所 苯并噁嗪类化合物及其药物用途
KR102641010B1 (ko) * 2023-12-04 2024-02-28 대한민국 실미타세르팁을 유효성분으로 포함하는 중증열성혈소판감소증후군 예방 또는 치료용 약학 조성물

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TW200715636A (en) 2005-10-04 2007-04-16 Antig Tech Co Ltd Method of controlling fuel concentration used in direct liquid fuel cell
US7956064B2 (en) 2006-09-01 2011-06-07 Cylene Pharmaceuticals, Inc. Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators
US8488289B2 (en) 2006-09-27 2013-07-16 International Rectifier Corporation Current protection circuit for intelligent power switch
US20090035609A1 (en) 2007-07-31 2009-02-05 Apple Inc. Intelligent universal rechargeable batteries for battery charging system for mobile and accessory devices

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150127611A (ko) * 2013-03-11 2015-11-17 노파르티스 아게 Wnt 억제제와 연관된 마커
JP2016513456A (ja) * 2013-03-11 2016-05-16 ノバルティス アーゲー Ｗｎｔ阻害剤に関連するマーカー
KR102194746B1 (ko) 2013-03-11 2020-12-24 노파르티스 아게 Wnt 억제제와 연관된 마커
JP2017507146A (ja) * 2014-02-18 2017-03-16 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Ｎｒｐ−１／ｏｂｒ複合体シグナル伝達経路により媒介される疾患の処置のための方法及び医薬組成物
JP2017524127A (ja) * 2014-07-18 2017-08-24 サノフイ 癌に罹患していることが疑われる患者のアフリベルセプトを用いた処置の結果を予測するための方法
JP2024508547A (ja) * 2021-03-01 2024-02-27 ケンブリッジ・エンタープライズ・リミテッド ベンゾ［ｃ］［２，６］ナフチリジン誘導体、組成物およびその治療的使用
WO2023190820A1 (ja) * 2022-03-30 2023-10-05 公立大学法人福島県立医科大学 抗ＣＫ２α抗体又はその断片

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IL218935A0 (en) 2012-07-31
BR112012007555A2 (pt) 2016-10-25
BR112012007555B1 (pt) 2020-09-29
CA2776278A1 (en) 2011-04-07
KR20120104196A (ko) 2012-09-20
AU2010300307A1 (en) 2012-05-24
IN2012DN03817A (https=) 2015-08-28
MX2012003997A (es) 2012-07-25
WO2011041785A1 (en) 2011-04-07
US20110212845A1 (en) 2011-09-01
EP2483686A1 (en) 2012-08-08

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