JP2013501775A5 - - Google Patents
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- Publication number
- JP2013501775A5 JP2013501775A5 JP2012524330A JP2012524330A JP2013501775A5 JP 2013501775 A5 JP2013501775 A5 JP 2013501775A5 JP 2012524330 A JP2012524330 A JP 2012524330A JP 2012524330 A JP2012524330 A JP 2012524330A JP 2013501775 A5 JP2013501775 A5 JP 2013501775A5
- Authority
- JP
- Japan
- Prior art keywords
- mycobacterium bovis
- bovis bcg
- composition
- killed
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241001467552 Mycobacterium bovis BCG Species 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 12
- 238000004108 freeze drying Methods 0.000 claims 6
- 230000001580 bacterial effect Effects 0.000 claims 4
- 238000007920 subcutaneous administration Methods 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 230000002035 prolonged effect Effects 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000012266 salt solution Substances 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09290627.0 | 2009-08-13 | ||
| EP09290627A EP2292260A1 (en) | 2009-08-13 | 2009-08-13 | Use of mycobacterium bovis BCG killed by extended freeze drying (EFD) for preventing or treating atherosclerosis |
| PCT/IB2010/053652 WO2011018769A1 (en) | 2009-08-13 | 2010-08-12 | Use of mycobacterium bovis bcg killed by extended freeze drying (efd) for preventing or treating atherosclerosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013501775A JP2013501775A (ja) | 2013-01-17 |
| JP2013501775A5 true JP2013501775A5 (https=) | 2013-06-06 |
| JP5762407B2 JP5762407B2 (ja) | 2015-08-12 |
Family
ID=41402542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012524330A Expired - Fee Related JP5762407B2 (ja) | 2009-08-13 | 2010-08-12 | アテローム性動脈硬化を予防又は治療するための、長期凍結乾燥（ｅｆｄ）により死滅したマイコバクテリウム・ボビスｂｃｇの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8414865B2 (https=) |
| EP (2) | EP2292260A1 (https=) |
| JP (1) | JP5762407B2 (https=) |
| CA (1) | CA2770915C (https=) |
| DK (1) | DK2464378T3 (https=) |
| ES (1) | ES2563577T3 (https=) |
| WO (1) | WO2011018769A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013106785B4 (de) | 2013-06-28 | 2018-11-29 | Pilz Auslandsbeteiligungen Gmbh | Verfahren zur Synchronisation eines Lichtgitters und auf diesem Verfahren beruhendes Lichtgitter |
| CN111879948A (zh) | 2013-10-17 | 2020-11-03 | 综合医院公司 | 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物 |
| JP6628071B2 (ja) * | 2015-04-28 | 2020-01-08 | 国立大学法人北海道大学 | 低密度リポタンパク質酸化抑制剤 |
| US11266730B2 (en) * | 2015-09-29 | 2022-03-08 | The General Hospital Corporation | Methods of treating and diagnosing disease using biomarkers for BCG therapy |
| ES2962407T3 (es) | 2018-12-04 | 2024-03-18 | Sabiotec Spin Off S L | Inmunoestimulante para su uso contra patógenos |
| WO2024180083A1 (en) * | 2023-02-27 | 2024-09-06 | Westfälische Wilhelms-Universität Münster | Oral vaccine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| US6350457B1 (en) * | 1999-06-02 | 2002-02-26 | Genesis Research & Development Corporation Limited | Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae |
| EP2316466B1 (en) | 2001-12-11 | 2013-08-21 | Institut Pasteur | Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation |
| CA2531261A1 (en) | 2005-12-21 | 2007-06-21 | Institut Pasteur | Control of intestinal inflammatory syndromes with a preparation of killed or non infectious bacteria |
| EP1916000A1 (en) * | 2006-10-26 | 2008-04-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of measles virus nucleoprotein for treating atherosclerosis |
| EP2087898A1 (en) * | 2008-02-06 | 2009-08-12 | Institut Pasteur | A preparation of mycobacterium bovis BCG killed by extended freeze drying (EFD) for treating rheumatoid arthritis |
-
2009
- 2009-08-13 EP EP09290627A patent/EP2292260A1/en not_active Withdrawn
-
2010
- 2010-08-12 WO PCT/IB2010/053652 patent/WO2011018769A1/en not_active Ceased
- 2010-08-12 DK DK10754572.5T patent/DK2464378T3/en active
- 2010-08-12 ES ES10754572.5T patent/ES2563577T3/es active Active
- 2010-08-12 CA CA2770915A patent/CA2770915C/en not_active Expired - Fee Related
- 2010-08-12 US US13/389,929 patent/US8414865B2/en not_active Expired - Fee Related
- 2010-08-12 JP JP2012524330A patent/JP5762407B2/ja not_active Expired - Fee Related
- 2010-08-12 EP EP10754572.5A patent/EP2464378B1/en not_active Not-in-force
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