JP2013500739A5 - - Google Patents
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- Publication number
- JP2013500739A5 JP2013500739A5 JP2012523432A JP2012523432A JP2013500739A5 JP 2013500739 A5 JP2013500739 A5 JP 2013500739A5 JP 2012523432 A JP2012523432 A JP 2012523432A JP 2012523432 A JP2012523432 A JP 2012523432A JP 2013500739 A5 JP2013500739 A5 JP 2013500739A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- antibody
- disease
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 53
- 229920001184 polypeptide Polymers 0.000 claims 42
- 108090000765 processed proteins & peptides Proteins 0.000 claims 42
- 102000004196 processed proteins & peptides Human genes 0.000 claims 42
- 108020004707 nucleic acids Proteins 0.000 claims 30
- 102000039446 nucleic acids Human genes 0.000 claims 30
- 150000007523 nucleic acids Chemical class 0.000 claims 30
- 201000010099 disease Diseases 0.000 claims 29
- 208000035475 disorder Diseases 0.000 claims 24
- 108090000623 proteins and genes Proteins 0.000 claims 23
- 102000004169 proteins and genes Human genes 0.000 claims 23
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 21
- 206010028980 Neoplasm Diseases 0.000 claims 18
- 201000011510 cancer Diseases 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 8
- 230000001939 inductive effect Effects 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 238000002360 preparation method Methods 0.000 claims 8
- 208000023275 Autoimmune disease Diseases 0.000 claims 7
- 230000001154 acute effect Effects 0.000 claims 7
- 230000035558 fertility Effects 0.000 claims 7
- 239000000523 sample Substances 0.000 claims 7
- 208000020450 carbohydrate metabolism disease Diseases 0.000 claims 6
- 238000001514 detection method Methods 0.000 claims 6
- 230000001900 immune effect Effects 0.000 claims 6
- 208000017745 inborn carbohydrate metabolic disease Diseases 0.000 claims 6
- 238000002054 transplantation Methods 0.000 claims 6
- 206010002261 Androgen deficiency Diseases 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 238000003745 diagnosis Methods 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 5
- 230000002068 genetic effect Effects 0.000 claims 5
- 230000004153 glucose metabolism Effects 0.000 claims 5
- 208000030090 Acute Disease Diseases 0.000 claims 4
- 108020004705 Codon Proteins 0.000 claims 4
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 4
- 208000029578 Muscle disease Diseases 0.000 claims 4
- 208000021642 Muscular disease Diseases 0.000 claims 4
- 208000008589 Obesity Diseases 0.000 claims 4
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 4
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 claims 4
- 208000037976 chronic inflammation Diseases 0.000 claims 4
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 4
- 206010012601 diabetes mellitus Diseases 0.000 claims 4
- 208000030172 endocrine system disease Diseases 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 235000020824 obesity Nutrition 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 208000035473 Communicable disease Diseases 0.000 claims 3
- 102000003746 Insulin Receptor Human genes 0.000 claims 3
- 108010001127 Insulin Receptor Proteins 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 230000001684 chronic effect Effects 0.000 claims 3
- 230000002708 enhancing effect Effects 0.000 claims 3
- 208000027866 inflammatory disease Diseases 0.000 claims 3
- 101100191603 Arabidopsis thaliana PRT6 gene Proteins 0.000 claims 2
- 102100025064 Cellular tumor antigen p53 Human genes 0.000 claims 2
- 208000017701 Endocrine disease Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229960003604 testosterone Drugs 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 108010078791 Carrier Proteins Proteins 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 229920002527 Glycogen Polymers 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 210000000628 antibody-producing cell Anatomy 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000023852 carbohydrate metabolic process Effects 0.000 claims 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000004136 fatty acid synthesis Effects 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 229940096919 glycogen Drugs 0.000 claims 1
- 230000034659 glycolysis Effects 0.000 claims 1
- 230000001771 impaired effect Effects 0.000 claims 1
- 230000004941 influx Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL200202 | 2009-08-02 | ||
| IL200202A IL200202A0 (en) | 2009-08-02 | 2009-08-02 | Novel proteins |
| PCT/IL2010/000621 WO2011016026A2 (en) | 2009-08-02 | 2010-08-02 | Novel proteins |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015047903A Division JP5833780B2 (ja) | 2009-08-02 | 2015-03-11 | 新規タンパク質 |
| JP2015155720A Division JP2015212302A (ja) | 2009-08-02 | 2015-08-06 | 新規タンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013500739A JP2013500739A (ja) | 2013-01-10 |
| JP2013500739A5 true JP2013500739A5 (enExample) | 2013-09-12 |
Family
ID=42263570
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523432A Pending JP2013500739A (ja) | 2009-08-02 | 2010-08-02 | 新規タンパク質 |
| JP2015047903A Expired - Fee Related JP5833780B2 (ja) | 2009-08-02 | 2015-03-11 | 新規タンパク質 |
| JP2015155720A Pending JP2015212302A (ja) | 2009-08-02 | 2015-08-06 | 新規タンパク質 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015047903A Expired - Fee Related JP5833780B2 (ja) | 2009-08-02 | 2015-03-11 | 新規タンパク質 |
| JP2015155720A Pending JP2015212302A (ja) | 2009-08-02 | 2015-08-06 | 新規タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8647632B2 (enExample) |
| EP (2) | EP2461829B1 (enExample) |
| JP (3) | JP2013500739A (enExample) |
| KR (1) | KR101623355B1 (enExample) |
| CN (1) | CN102596247B (enExample) |
| AU (1) | AU2010280368B2 (enExample) |
| CA (1) | CA2769001C (enExample) |
| IL (3) | IL200202A0 (enExample) |
| IN (1) | IN2012DN00879A (enExample) |
| SG (2) | SG10201404735VA (enExample) |
| WO (1) | WO2011016026A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2742061A4 (en) * | 2011-08-08 | 2015-05-27 | Two To Biotech Ltd | NOVEL PEPTIDES, COMPOSITIONS COMPRISING THEM AND USES THEREOF IN METHODS FOR THE TREATMENT OF METABOLIC, CARDIAC AND IMMUNE DISORDERS |
| SG11201605354WA (en) * | 2014-01-02 | 2016-07-28 | Two To Biotech Ltd | Novel polypeptides |
| CN104262468B (zh) * | 2014-09-28 | 2017-01-18 | 新乡医学院 | 一种葡萄糖转运蛋白抑制多肽及其制备方法、应用 |
| ES2746157T3 (es) | 2015-03-05 | 2020-03-04 | Sekisui Specialty Chemicals Am | Dispersante de PVOH para polimerización de VCM |
| US11427872B2 (en) | 2015-12-11 | 2022-08-30 | National University Corporation Kochi University | Marker for pancreatic cancer and intraductal papillary mucinous neoplasms |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US5286846A (en) | 1991-06-14 | 1994-02-15 | The Government Of The United States Of America As Represented By The Dept. Of Health And Human Services | Amino acid derivative and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides |
| US6551795B1 (en) * | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
| WO2001087316A2 (en) * | 2000-05-15 | 2001-11-22 | Braswell, Glenn, A. | Composition and method for increasing testosterone levels |
| EP1296706B1 (en) * | 2000-06-19 | 2006-02-22 | The Uab Research Foundation | Osteoclast secreted chemokine and uses thereof |
| AU2003900747A0 (en) * | 2003-02-18 | 2003-03-06 | Garvan Institute Of Medical Research | Diagnosis and treatment of pancreatic cancer |
| US20080206231A1 (en) * | 2004-10-05 | 2008-08-28 | Oregon Health And Science University | Compositions and Methods for Treating Disease |
| US20080248134A1 (en) * | 2005-05-04 | 2008-10-09 | Auckland Uniservices Limited | Oral compositions, use and combinations of N-[2-(dimethylamino)ethyl]-2,6 dimethyl-1-oxo-1,2-dihydrobenzo[b]-1,6-naphthyridine-4-carboxamide and closely related analogues thereof |
| US20090018031A1 (en) * | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
-
2009
- 2009-08-02 IL IL200202A patent/IL200202A0/en unknown
-
2010
- 2010-08-02 WO PCT/IL2010/000621 patent/WO2011016026A2/en not_active Ceased
- 2010-08-02 KR KR1020127004449A patent/KR101623355B1/ko not_active Expired - Fee Related
- 2010-08-02 IN IN879DEN2012 patent/IN2012DN00879A/en unknown
- 2010-08-02 EP EP10806144.1A patent/EP2461829B1/en not_active Not-in-force
- 2010-08-02 CA CA2769001A patent/CA2769001C/en not_active Expired - Fee Related
- 2010-08-02 JP JP2012523432A patent/JP2013500739A/ja active Pending
- 2010-08-02 AU AU2010280368A patent/AU2010280368B2/en not_active Ceased
- 2010-08-02 SG SG10201404735VA patent/SG10201404735VA/en unknown
- 2010-08-02 SG SG2012005070A patent/SG178097A1/en unknown
- 2010-08-02 CN CN201080044688.3A patent/CN102596247B/zh not_active Expired - Fee Related
- 2010-08-02 EP EP15182357.2A patent/EP2985035A1/en not_active Withdrawn
- 2010-08-02 US US13/387,392 patent/US8647632B2/en active Active
-
2012
- 2012-01-26 IL IL217758A patent/IL217758A/en not_active IP Right Cessation
-
2015
- 2015-03-11 JP JP2015047903A patent/JP5833780B2/ja not_active Expired - Fee Related
- 2015-07-23 IL IL240134A patent/IL240134A/en not_active IP Right Cessation
- 2015-08-06 JP JP2015155720A patent/JP2015212302A/ja active Pending
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