JP2013256473A5 - - Google Patents
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- Publication number
- JP2013256473A5 JP2013256473A5 JP2012134048A JP2012134048A JP2013256473A5 JP 2013256473 A5 JP2013256473 A5 JP 2013256473A5 JP 2012134048 A JP2012134048 A JP 2012134048A JP 2012134048 A JP2012134048 A JP 2012134048A JP 2013256473 A5 JP2013256473 A5 JP 2013256473A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- hydrogen atom
- compound represented
- hydroxyl group
- methyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims 4
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 206010040880 Skin irritation Diseases 0.000 claims 3
- 230000036556 skin irritation Effects 0.000 claims 3
- 231100000475 skin irritation Toxicity 0.000 claims 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 101000764872 Homo sapiens Transient receptor potential cation channel subfamily A member 1 Proteins 0.000 claims 2
- DTGKSKDOIYIVQL-MRTMQBJTSA-N Isoborneol Natural products C1C[C@@]2(C)[C@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-MRTMQBJTSA-N 0.000 claims 2
- 102100026186 Transient receptor potential cation channel subfamily A member 1 Human genes 0.000 claims 2
- 229940116229 borneol Drugs 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 230000000116 mitigating effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012134048A JP6061508B2 (ja) | 2012-06-13 | 2012-06-13 | Trpa1活性抑制剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012134048A JP6061508B2 (ja) | 2012-06-13 | 2012-06-13 | Trpa1活性抑制剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013256473A JP2013256473A (ja) | 2013-12-26 |
| JP2013256473A5 true JP2013256473A5 (enExample) | 2014-10-09 |
| JP6061508B2 JP6061508B2 (ja) | 2017-01-18 |
Family
ID=49953237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012134048A Active JP6061508B2 (ja) | 2012-06-13 | 2012-06-13 | Trpa1活性抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6061508B2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6410352B2 (ja) * | 2014-10-10 | 2018-10-24 | 花王株式会社 | 刺激感緩和剤 |
| JP6804162B2 (ja) * | 2018-09-14 | 2020-12-23 | 株式会社マンダム | 皮膚外用剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003206239A (ja) * | 2001-12-28 | 2003-07-22 | Lion Corp | 温感組成物及び外用剤組成物 |
| JP2007077143A (ja) * | 2005-08-19 | 2007-03-29 | Rohto Pharmaceut Co Ltd | アシタザノラスト含有組成物 |
| CN101292976B (zh) * | 2008-06-26 | 2010-07-28 | 贵州宏宇药业有限公司 | 一种含有1,8-桉叶素和艾纳香素的药物组合物及其用途 |
| RU2573293C2 (ru) * | 2010-03-26 | 2016-01-20 | Филип Моррис Продактс С.А. | Ингибирование раздражающих ощущений при потреблении некурительных табачных продуктов |
-
2012
- 2012-06-13 JP JP2012134048A patent/JP6061508B2/ja active Active
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