JP2013048628A5 - - Google Patents

Download PDF

Info

Publication number
JP2013048628A5
JP2013048628A5 JP2012226780A JP2012226780A JP2013048628A5 JP 2013048628 A5 JP2013048628 A5 JP 2013048628A5 JP 2012226780 A JP2012226780 A JP 2012226780A JP 2012226780 A JP2012226780 A JP 2012226780A JP 2013048628 A5 JP2013048628 A5 JP 2013048628A5
Authority
JP
Japan
Prior art keywords
substrate
ire
nucleotide
moiety
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012226780A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013048628A (ja
Filing date
Publication date
Priority claimed from US11/266,603 external-priority patent/US8017331B2/en
Application filed filed Critical
Publication of JP2013048628A publication Critical patent/JP2013048628A/ja
Publication of JP2013048628A5 publication Critical patent/JP2013048628A5/ja
Pending legal-status Critical Current

Links

JP2012226780A 2005-11-04 2012-10-12 IRE−1α基質 Pending JP2013048628A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/266,603 2005-11-04
US11/266,603 US8017331B2 (en) 2005-11-04 2005-11-04 IRE-1α substrates

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008538855A Division JP2009514526A (ja) 2005-11-04 2005-11-07 IRE−1α基質

Publications (2)

Publication Number Publication Date
JP2013048628A JP2013048628A (ja) 2013-03-14
JP2013048628A5 true JP2013048628A5 (https=) 2014-01-16

Family

ID=38004190

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008538855A Withdrawn JP2009514526A (ja) 2005-11-04 2005-11-07 IRE−1α基質
JP2012226780A Pending JP2013048628A (ja) 2005-11-04 2012-10-12 IRE−1α基質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008538855A Withdrawn JP2009514526A (ja) 2005-11-04 2005-11-07 IRE−1α基質

Country Status (4)

Country Link
US (2) US8017331B2 (https=)
EP (1) EP1943262B1 (https=)
JP (2) JP2009514526A (https=)
WO (1) WO2007053151A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009013332A (es) 2007-06-08 2010-01-25 Mannkind Corp Inhibidores de ire-1 alfa.
CN103079558B (zh) 2010-04-05 2025-09-12 上海复星医药产业发展有限公司 IRE-1α抑制剂
US9603949B2 (en) 2011-09-01 2017-03-28 University Of Iowa Research Foundation Oligonucleotide-based probes for detection of bacterial nucleases
WO2014141940A1 (ja) 2013-03-12 2014-09-18 株式会社ジェイテクト 風力発電装置
US10619219B2 (en) 2014-02-07 2020-04-14 University Of Iowa Research Foundation Oligonucleotide-based probes and methods for detection of microbes
EP3548476A4 (en) * 2016-12-02 2020-05-20 Quentis Therapeutics, Inc. SMALL MOLECULAR IRE1 INHIBITORS
WO2018222917A1 (en) * 2017-06-01 2018-12-06 Quentis Therapeutics, Inc. Ire1 small molecule inhibitors
JP7126084B2 (ja) 2017-06-01 2022-08-26 コーネル ユニバーシティー Ire1小分子阻害薬
US10392367B2 (en) 2017-06-01 2019-08-27 Quentis Therapeutics, Inc. IRE1 small molecule inhibitors
EP3688181A4 (en) 2017-09-29 2021-06-16 University of Iowa Research Foundation COMPOSITIONS AND METHOD OF DETECTING DIGITAL NUCLEASES
CN110950877B (zh) * 2019-12-11 2022-06-28 齐鲁工业大学 一种双检测荧光探针、制备方法及其在检测硫化氢和铜离子中的应用
US20240287572A1 (en) * 2021-04-16 2024-08-29 Meso Scale Technologies, Llc. Methods, compositions, and kits for detecting hydrolase enzyme activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05137600A (ja) * 1991-05-15 1993-06-01 Amoco Corp ビブリオ属細菌を検出するための組成物及び方法
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5610012A (en) * 1994-04-08 1997-03-11 Wisconsin Alumni Research Foundation DNA probes specific for virulent listeria monocytogenes
US5871983A (en) * 1996-09-13 1999-02-16 Eli Lilly And Company Glucosyltransferase gene GTFE from amycolatopsis orientalis
GB9626074D0 (en) * 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
JPH1156398A (ja) * 1997-08-11 1999-03-02 Hamamatsu Photonics Kk 二本鎖核酸分解酵素活性の測定方法
ATE377093T1 (de) * 2000-07-07 2007-11-15 Visigen Biotechnologies Inc Sequenzbestimmung in echtzeit
US20020187484A1 (en) * 2000-11-27 2002-12-12 Jon Thorson Molecular break lights probes for detecting nucleotide cleavage
JP4537053B2 (ja) * 2001-06-25 2010-09-01 ジョージア テック リサーチ コーポレーション 二重共鳴エネルギー転移核酸プローブ

Similar Documents

Publication Publication Date Title
JP2013048628A5 (https=)
Peng et al. A nonfluorescent, broad-range quencher dye for Förster resonance energy transfer assays
Yan et al. Chemiluminescence resonance energy transfer: From mechanisms to analytical applications
Lin et al. Fluorescence lifetime characterization of novel low-pH probes
WO2010096388A4 (en) Quenched dendrimeric dyes for florescence detection
JP2008513038A5 (https=)
Zhang et al. Hybridization induced fluorescence turn-on of AIEgen–oligonucleotide conjugates for specific DNA detection
Chiba et al. Artificial DNAs based on alkynyl C‐nucleosides as a superior scaffold for homo‐and heteroexcimer emissions
JP2012518072A5 (https=)
EP2118658B1 (en) Improved homogeneous luminescence bioassay
Fonseca et al. Selective Fluorescence Quenching in Cationic Fluorene‐Thiophene Diblock Copolymers for Ratiometric Sensing of Anions
CN103588960A (zh) 一类非标记离子型共轭聚电解质及其合成方法、在生物检测的应用
Endo et al. Pyrene‐stacked nanostructures constructed in the recombinant tobacco mosaic virus rod scaffold
US7566783B2 (en) Long wavelength long lifetime luminophores
Walter et al. Development of a Wavelength‐Shifting Fluorescent Module for the Adenosine Aptamer Using Photostable Cyanine Dyes
Gan et al. DNA‐induced circularly polarized luminescence of helicene racemates
Peng et al. CdSe/ZnS core shell quantum dot-based FRET binary oligonucleotide probes for detection of nucleic acids
Saikiran et al. Efficient near infrared fluorescence detection of elastase enzyme using peptide-bound unsymmetrical squaraine dye
Hu et al. A multifunctional DNA nanostructure based on multicolor FRET for nuclease activity assay
Varghese et al. Red–white–blue emission switching molecular beacons: Ratiometric multicolour DNA hybridization probes
Yongpruksa et al. Benzothiazines in organic synthesis. Synthesis of fluorescent 7-amino-2, 1-benzothiazines
WO2005030979A2 (en) Dark quenchers for fluorescence resonance energy transfer (fret) in bioassays
US7790392B2 (en) Homogeneous luminescence bioassay
Bao et al. Luminescent polypeptides
KR101249493B1 (ko) 핵산효소-분자비콘을 이용한 핵산의 검출방법