JP2012530725A5 - - Google Patents
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- Publication number
- JP2012530725A5 JP2012530725A5 JP2012516450A JP2012516450A JP2012530725A5 JP 2012530725 A5 JP2012530725 A5 JP 2012530725A5 JP 2012516450 A JP2012516450 A JP 2012516450A JP 2012516450 A JP2012516450 A JP 2012516450A JP 2012530725 A5 JP2012530725 A5 JP 2012530725A5
- Authority
- JP
- Japan
- Prior art keywords
- trpv6
- binding peptide
- composition
- compound
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003569 TRPV6 Human genes 0.000 claims 37
- 101150096736 TRPV6 gene Proteins 0.000 claims 37
- 150000001875 compounds Chemical class 0.000 claims 23
- 108090000765 processed proteins & peptides Proteins 0.000 claims 19
- 206010028980 Neoplasm Diseases 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 11
- 239000000523 sample Substances 0.000 claims 11
- 201000011510 cancer Diseases 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 210000001124 body fluid Anatomy 0.000 claims 4
- 239000010839 body fluid Substances 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 4
- 239000002405 nuclear magnetic resonance imaging agent Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical group [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 claims 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 229940123237 Taxane Drugs 0.000 claims 1
- 229940045799 anthracyclines and related substance Drugs 0.000 claims 1
- 229940041181 antineoplastic drug Drugs 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000002595 magnetic resonance imaging Methods 0.000 claims 1
- 230000001769 paralizing effect Effects 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22083309P | 2009-06-26 | 2009-06-26 | |
| US61/220,833 | 2009-06-26 | ||
| US24463409P | 2009-09-22 | 2009-09-22 | |
| US61/244,634 | 2009-09-22 | ||
| PCT/CA2010/000971 WO2010148501A1 (en) | 2009-06-26 | 2010-06-28 | Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530725A JP2012530725A (ja) | 2012-12-06 |
| JP2012530725A5 true JP2012530725A5 (https=) | 2013-08-15 |
| JP5836940B2 JP5836940B2 (ja) | 2015-12-24 |
Family
ID=43381003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516450A Active JP5836940B2 (ja) | 2009-06-26 | 2010-06-28 | ソリシジン由来ペプチドならびにｔｒｐｖ−６がんの検出および薬剤送達のための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20100329983A1 (https=) |
| EP (1) | EP2445932B1 (https=) |
| JP (1) | JP5836940B2 (https=) |
| BR (1) | BRPI1012675A2 (https=) |
| CA (1) | CA2766272C (https=) |
| ES (1) | ES2670588T3 (https=) |
| MX (1) | MX2012000086A (https=) |
| WO (1) | WO2010148501A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2445932B1 (en) | 2009-06-26 | 2018-02-28 | Soricimed Biopharma Inc. | Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery |
| US20130116404A1 (en) * | 2011-11-08 | 2013-05-09 | Case Western Reserve University | Targeted non-invasive imaging probes of egfr expressing cells |
| EP2895504B1 (en) * | 2012-09-14 | 2019-05-08 | John M. Stewart | Trpv3 agonists for the treatment of skin conditions |
| WO2019183633A1 (en) | 2018-03-23 | 2019-09-26 | Case Western Reserve Univeristy | Psma targeted conjugate compounds and uses thereof |
| CN111484982A (zh) * | 2020-05-14 | 2020-08-04 | 西南民族大学 | 一种人结直肠腺癌细胞trpv1基因敲除细胞株及应用 |
| US20260116965A1 (en) * | 2021-01-15 | 2026-04-30 | Coherent Biopharma (Suzhou) , Limited | Anti-trpv6 monoclonal antibody and application thereof |
| AU2022365387A1 (en) * | 2021-10-14 | 2024-05-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies against extracellular epitopes of human trpv6 channel and their diagnostic and therapeutic uses |
| US20250332265A1 (en) | 2021-11-09 | 2025-10-30 | Case Western Reserve University | Psma targeted conjugate compounds and uses thereof |
| CN118846104A (zh) * | 2024-06-27 | 2024-10-29 | 河北工业大学 | 一种近红外响应纳米复合物及其制备方法和应用 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7002A (en) * | 1850-01-08 | Obe-washek | ||
| GB2161165A (en) | 1984-06-12 | 1986-01-08 | Cambridge Patent Dev | Secondary antibodies |
| DK255887D0 (da) | 1987-05-20 | 1987-05-20 | Claus Koch | Immunoassay |
| GB8722018D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| US5496548A (en) | 1987-09-18 | 1996-03-05 | National Blood Authority | Human anti-RH(D) monoclonal antibodies, cell lines and methods of use of antibodies in immunoassays |
| US5688657A (en) | 1988-03-31 | 1997-11-18 | International Bio-Immune Systems, Inc. | Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor |
| ATE147634T1 (de) | 1988-12-19 | 1997-02-15 | American Cyanamid Co | Produkte zur behandlung des endotoxin -schocks bei einem säugetier |
| AU648022B2 (en) | 1989-03-14 | 1994-04-14 | Bionebraska, Inc. | Monoclonal antibodies for metallic cations on small molecules |
| US5500345A (en) | 1989-04-25 | 1996-03-19 | Iatron Laboratories, Inc. | Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein |
| CA2025266A1 (en) | 1989-10-04 | 1991-04-05 | Kiyoshi Kobayashi | Anti-hcg-.beta. core monoclonal antibody, its production and use |
| WO1991014452A1 (en) | 1990-03-27 | 1991-10-03 | The Salk Institute For Biological Studies | Method for inhibiting cell growth and compositions useful therefor |
| US5510241A (en) | 1990-10-01 | 1996-04-23 | The Minister Of Agriculture, Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britian And Northern Ireland | Method of testing for the presence of Salmonella serotypes expressing Salmonella enteritidis fimbrial antigen (SEFA) and reagents therefore |
| US5225331A (en) | 1991-04-25 | 1993-07-06 | National Research Council Of Canada | Immunoassay for detecting group b streptococcus |
| AU667533B2 (en) | 1992-03-26 | 1996-03-28 | Microcarb, Inc. | Monospecific polyclonal antibodies to shiga-like toxins |
| AU4231393A (en) | 1992-05-08 | 1993-12-13 | Genentech Inc. | Antibodies to leukemia inhibitory factor |
| US5424286A (en) * | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| JPH10236963A (ja) | 1997-02-26 | 1998-09-08 | Sagami Chem Res Center | カルシウムチャンネル拮抗剤 |
| AU7389098A (en) * | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| US6946475B1 (en) * | 1999-04-07 | 2005-09-20 | University Of Virginia Patent Foundation | Anticancer calcium channel blockers |
| EP1165508B1 (en) | 1999-04-07 | 2004-06-23 | The University of Virginia Patent Foundation | Anticancer calcium channel blockers |
| US6534642B1 (en) * | 1999-07-09 | 2003-03-18 | Matthias A. Hediger | Compositions corresponding to a calcium transporter and methods of making and using same |
| US6348317B1 (en) | 1999-11-18 | 2002-02-19 | The Arizona Board Of Regents | Fluorescent and DNA cleavage properties of peptide/dye conjugates |
| US20040001827A1 (en) | 2002-06-28 | 2004-01-01 | Dennis Mark S. | Serum albumin binding peptides for tumor targeting |
| US7176037B2 (en) | 2000-07-13 | 2007-02-13 | The Scripps Research Institute | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| DE60134178D1 (de) | 2000-07-28 | 2008-07-03 | Ulrich Wissenbach | Trp8 krebsmarker |
| AU2003281200A1 (en) | 2002-07-03 | 2004-01-23 | Tasuku Honjo | Immunopotentiating compositions |
| US7119168B2 (en) * | 2002-11-18 | 2006-10-10 | Bioprospecting Nb Inc. | Paralytic peptide for use in neuromuscular therapy |
| CA2544467C (en) * | 2002-11-18 | 2014-02-18 | John M. Stewart | Paralytic peptide for use in neuromuscular therapy |
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| PT1907424E (pt) | 2005-07-01 | 2015-10-09 | Squibb & Sons Llc | Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1) |
| JP5749154B2 (ja) * | 2008-03-19 | 2015-07-15 | ソリシメド・バイオファーマ・インコーポレーテッド | Ｔｒｐｖ６カルシウムチャネル活性阻害による癌治療のためのペプチド組成物 |
| US9181342B2 (en) | 2008-09-12 | 2015-11-10 | Isis Innovation Limited | PD-1 specific antibodies and uses thereof |
| US8552154B2 (en) | 2008-09-26 | 2013-10-08 | Emory University | Anti-PD-L1 antibodies and uses therefor |
| JP5245853B2 (ja) | 2009-01-19 | 2013-07-24 | セイコーエプソン株式会社 | 画像形成装置 |
| JP5844159B2 (ja) | 2009-02-09 | 2016-01-13 | ユニヴェルシテ デクス−マルセイユＵｎｉｖｅｒｓｉｔｅ Ｄ’Ａｉｘ−Ｍａｒｓｅｉｌｌｅ | Ｐｄ−１抗体およびｐｄ−ｌ１抗体ならびにその使用 |
| EP2445932B1 (en) | 2009-06-26 | 2018-02-28 | Soricimed Biopharma Inc. | Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery |
| EP2545078A1 (en) | 2010-03-11 | 2013-01-16 | UCB Pharma, S.A. | Pd-1 antibody |
| TW201134488A (en) | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| EP2895504B1 (en) | 2012-09-14 | 2019-05-08 | John M. Stewart | Trpv3 agonists for the treatment of skin conditions |
| CN112552401B (zh) | 2013-09-13 | 2023-08-25 | 广州百济神州生物制药有限公司 | 抗pd1抗体及其作为治疗剂与诊断剂的用途 |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| PE20170255A1 (es) | 2014-01-24 | 2017-03-22 | Dana Farber Cancer Inst Inc | Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas |
| AU2015243537B2 (en) | 2014-04-08 | 2020-10-22 | The Methodist Hospital | INOS-inhibitory compositions and their use as breast cancer therapeutics |
| JP6772199B2 (ja) | 2015-08-11 | 2020-10-21 | コヒレント バイオファーマ | 多リガンド−薬物複合体及びその使用 |
| EP3439658B1 (en) | 2016-04-04 | 2021-11-24 | ChemoCentryx, Inc. | Soluble c5ar antagonists |
| KR20180133442A (ko) | 2016-04-13 | 2018-12-14 | 비비아 바이오테크 에스.엘. | 생체외 bite 활성화된 t 세포 |
| CA3083950A1 (en) | 2017-12-01 | 2019-06-06 | Soricimed Biopharma Inc. | Trpv6 inhibitors and combination therapies for treating cancers |
-
2010
- 2010-06-28 EP EP10791109.1A patent/EP2445932B1/en active Active
- 2010-06-28 ES ES10791109.1T patent/ES2670588T3/es active Active
- 2010-06-28 JP JP2012516450A patent/JP5836940B2/ja active Active
- 2010-06-28 WO PCT/CA2010/000971 patent/WO2010148501A1/en not_active Ceased
- 2010-06-28 US US12/824,935 patent/US20100329983A1/en not_active Abandoned
- 2010-06-28 CA CA2766272A patent/CA2766272C/en active Active
- 2010-06-28 BR BRPI1012675A patent/BRPI1012675A2/pt not_active IP Right Cessation
- 2010-06-28 MX MX2012000086A patent/MX2012000086A/es not_active Application Discontinuation
-
2014
- 2014-12-22 US US14/579,157 patent/US10064964B2/en active Active
-
2018
- 2018-07-26 US US16/046,786 patent/US11090396B2/en active Active
-
2021
- 2021-07-15 US US17/376,670 patent/US12458618B2/en active Active
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