JP2012530725A5 - - Google Patents
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- Publication number
- JP2012530725A5 JP2012530725A5 JP2012516450A JP2012516450A JP2012530725A5 JP 2012530725 A5 JP2012530725 A5 JP 2012530725A5 JP 2012516450 A JP2012516450 A JP 2012516450A JP 2012516450 A JP2012516450 A JP 2012516450A JP 2012530725 A5 JP2012530725 A5 JP 2012530725A5
- Authority
- JP
- Japan
- Prior art keywords
- trpv6
- binding peptide
- composition
- compound
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003569 TRPV6 Human genes 0.000 claims 37
- 101150096736 TRPV6 gene Proteins 0.000 claims 37
- 150000001875 compounds Chemical class 0.000 claims 23
- 108090000765 processed proteins & peptides Proteins 0.000 claims 19
- 206010028980 Neoplasm Diseases 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 11
- 239000000523 sample Substances 0.000 claims 11
- 201000011510 cancer Diseases 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 210000001124 body fluid Anatomy 0.000 claims 4
- 239000010839 body fluid Substances 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 4
- 239000002405 nuclear magnetic resonance imaging agent Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- WTFXARWRTYJXII-UHFFFAOYSA-N iron(2+);iron(3+);oxygen(2-) Chemical group [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3] WTFXARWRTYJXII-UHFFFAOYSA-N 0.000 claims 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 229940123237 Taxane Drugs 0.000 claims 1
- 229940045799 anthracyclines and related substance Drugs 0.000 claims 1
- 229940041181 antineoplastic drug Drugs 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000002595 magnetic resonance imaging Methods 0.000 claims 1
- 230000001769 paralizing effect Effects 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000001052 transient effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22083309P | 2009-06-26 | 2009-06-26 | |
| US61/220,833 | 2009-06-26 | ||
| US24463409P | 2009-09-22 | 2009-09-22 | |
| US61/244,634 | 2009-09-22 | ||
| PCT/CA2010/000971 WO2010148501A1 (en) | 2009-06-26 | 2010-06-28 | Soricidin derived peptides and methods for the detection of trpv-6 cancers and drug delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530725A JP2012530725A (ja) | 2012-12-06 |
| JP2012530725A5 true JP2012530725A5 (enExample) | 2013-08-15 |
| JP5836940B2 JP5836940B2 (ja) | 2015-12-24 |
Family
ID=43381003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516450A Active JP5836940B2 (ja) | 2009-06-26 | 2010-06-28 | ソリシジン由来ペプチドならびにｔｒｐｖ−６がんの検出および薬剤送達のための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20100329983A1 (enExample) |
| EP (1) | EP2445932B1 (enExample) |
| JP (1) | JP5836940B2 (enExample) |
| BR (1) | BRPI1012675A2 (enExample) |
| CA (1) | CA2766272C (enExample) |
| ES (1) | ES2670588T3 (enExample) |
| MX (1) | MX2012000086A (enExample) |
| WO (1) | WO2010148501A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1012675A2 (pt) | 2009-06-26 | 2016-04-05 | Soricimed Biopharma Inc | compostos e métodos para a detecção de cânceres expressando trpv-6 e liberação de fármacos |
| US20130116404A1 (en) * | 2011-11-08 | 2013-05-09 | Case Western Reserve University | Targeted non-invasive imaging probes of egfr expressing cells |
| EP2895504B1 (en) * | 2012-09-14 | 2019-05-08 | John M. Stewart | Trpv3 agonists for the treatment of skin conditions |
| WO2019183633A1 (en) | 2018-03-23 | 2019-09-26 | Case Western Reserve Univeristy | Psma targeted conjugate compounds and uses thereof |
| CN111484982A (zh) * | 2020-05-14 | 2020-08-04 | 西南民族大学 | 一种人结直肠腺癌细胞trpv1基因敲除细胞株及应用 |
| KR20230132450A (ko) * | 2021-01-15 | 2023-09-15 | 코히런트 바이오파마 (쑤저우), 리미티드 | 항trpv6 단일 클론 항체 및 그 응용 |
| WO2023062226A2 (en) * | 2021-10-14 | 2023-04-20 | Universite De Lille | Antibodies against extracellular epitopes of human trpv6 channel and their diagnostic and therapeutic uses |
| US20250332265A1 (en) | 2021-11-09 | 2025-10-30 | Case Western Reserve University | Psma targeted conjugate compounds and uses thereof |
| CN118846104A (zh) * | 2024-06-27 | 2024-10-29 | 河北工业大学 | 一种近红外响应纳米复合物及其制备方法和应用 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7002A (en) * | 1850-01-08 | Obe-washek | ||
| GB2161165A (en) | 1984-06-12 | 1986-01-08 | Cambridge Patent Dev | Secondary antibodies |
| DK255887D0 (da) | 1987-05-20 | 1987-05-20 | Claus Koch | Immunoassay |
| US5496548A (en) | 1987-09-18 | 1996-03-05 | National Blood Authority | Human anti-RH(D) monoclonal antibodies, cell lines and methods of use of antibodies in immunoassays |
| GB8722018D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| US5688657A (en) | 1988-03-31 | 1997-11-18 | International Bio-Immune Systems, Inc. | Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor |
| SG43205A1 (en) | 1988-12-19 | 1997-10-17 | American Cyanamid Co | A method for the treatment of endotoxic shock in a mammal |
| CA2047717C (en) | 1989-03-14 | 2000-08-01 | Fred W. Wagner | Monoclonal antibodies for small moieties, methods therefor |
| US5500345A (en) | 1989-04-25 | 1996-03-19 | Iatron Laboratories, Inc. | Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein |
| CA2025266A1 (en) | 1989-10-04 | 1991-04-05 | Kiyoshi Kobayashi | Anti-hcg-.beta. core monoclonal antibody, its production and use |
| ATE154245T1 (de) | 1990-03-27 | 1997-06-15 | Salk Inst For Biological Studi | Verfahren zur zellwachstumshinderung und dazu nützliche verbindungen |
| US5510241A (en) | 1990-10-01 | 1996-04-23 | The Minister Of Agriculture, Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britian And Northern Ireland | Method of testing for the presence of Salmonella serotypes expressing Salmonella enteritidis fimbrial antigen (SEFA) and reagents therefore |
| US5225331A (en) | 1991-04-25 | 1993-07-06 | National Research Council Of Canada | Immunoassay for detecting group b streptococcus |
| CA2132953C (en) | 1992-03-26 | 2001-01-30 | Howard C. Krivan | Monospecific polyclonal antibodies to shiga-like toxins |
| AU4231393A (en) | 1992-05-08 | 1993-12-13 | Genentech Inc. | Antibodies to leukemia inhibitory factor |
| US5424286A (en) * | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| JPH10236963A (ja) | 1997-02-26 | 1998-09-08 | Sagami Chem Res Center | カルシウムチャンネル拮抗剤 |
| US6326020B1 (en) * | 1997-05-16 | 2001-12-04 | Children's Medical Center Corporation | Local anesthetic formulations |
| US6946475B1 (en) * | 1999-04-07 | 2005-09-20 | University Of Virginia Patent Foundation | Anticancer calcium channel blockers |
| ATE269848T1 (de) | 1999-04-07 | 2004-07-15 | Univ Virginia | Calciumkanalblocker als antikrebsmittel |
| US6534642B1 (en) * | 1999-07-09 | 2003-03-18 | Matthias A. Hediger | Compositions corresponding to a calcium transporter and methods of making and using same |
| US6348317B1 (en) | 1999-11-18 | 2002-02-19 | The Arizona Board Of Regents | Fluorescent and DNA cleavage properties of peptide/dye conjugates |
| US20040001827A1 (en) | 2002-06-28 | 2004-01-01 | Dennis Mark S. | Serum albumin binding peptides for tumor targeting |
| US7176037B2 (en) | 2000-07-13 | 2007-02-13 | The Scripps Research Institute | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| ATE396266T1 (de) | 2000-07-28 | 2008-06-15 | Ulrich Wissenbach | Trp8 krebsmarker |
| ATE481985T1 (de) | 2002-07-03 | 2010-10-15 | Ono Pharmaceutical Co | Immunpotenzierende zusammensetzungen |
| US7119168B2 (en) * | 2002-11-18 | 2006-10-10 | Bioprospecting Nb Inc. | Paralytic peptide for use in neuromuscular therapy |
| ATE384078T1 (de) | 2002-11-18 | 2008-02-15 | Bioprospecting Nb Inc | Paralytisches peptide von der spitzmaus sowie dessen nutzung in der therapie von neuromuskulären krankheiten |
| KR101498834B1 (ko) | 2005-05-09 | 2015-03-05 | 오노 야꾸힝 고교 가부시키가이샤 | 예정 사멸 인자 1(ｐｄ-1)에 대한 인간 모노클로날 항체, 및 항-ｐｄ-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법 |
| HRP20080053A2 (hr) | 2005-07-01 | 2009-08-31 | Medarex | Ljudska monoklonska protutijela na ligand 1 za programiranu smrt stanice (pd-l1) |
| EP2268665B1 (en) * | 2008-03-19 | 2014-11-12 | Soricimed Biopharma Inc. | Peptide composition for cancer treatment by inhibiting trpv6 calcium channel activity |
| US9181342B2 (en) | 2008-09-12 | 2015-11-10 | Isis Innovation Limited | PD-1 specific antibodies and uses thereof |
| EP3133086B1 (en) | 2008-09-26 | 2018-08-01 | Dana-Farber Cancer Institute, Inc. | Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof |
| JP5245853B2 (ja) | 2009-01-19 | 2013-07-24 | セイコーエプソン株式会社 | 画像形成装置 |
| US8741295B2 (en) | 2009-02-09 | 2014-06-03 | Universite De La Mediterranee | PD-1 antibodies and PD-L1 antibodies and uses thereof |
| BRPI1012675A2 (pt) * | 2009-06-26 | 2016-04-05 | Soricimed Biopharma Inc | compostos e métodos para a detecção de cânceres expressando trpv-6 e liberação de fármacos |
| TW201134488A (en) | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| US8993731B2 (en) | 2010-03-11 | 2015-03-31 | Ucb Biopharma Sprl | PD-1 antibody |
| EP2895504B1 (en) | 2012-09-14 | 2019-05-08 | John M. Stewart | Trpv3 agonists for the treatment of skin conditions |
| EA034666B1 (ru) | 2013-09-13 | 2020-03-04 | Бейджин Свитзерланд Гмбх | Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| CA2979530C (en) | 2014-04-08 | 2023-10-03 | The Methodist Hospital | Inos-inhibitory compositions and their use as breast cancer therapeutics |
| JP6772199B2 (ja) | 2015-08-11 | 2020-10-21 | コヒレント バイオファーマ | 多リガンド−薬物複合体及びその使用 |
| WO2017176620A2 (en) | 2016-04-04 | 2017-10-12 | Chemocentryx, Inc. | SOLUBLE C5aR ANTAGONISTS |
| IL295538B2 (en) | 2016-04-13 | 2024-02-01 | Vivia Biotech Sl | In vitro bite-activated T cells |
| EP3716991A4 (en) | 2017-12-01 | 2021-09-08 | Soricimed Biopharma Inc. | TRPV6 INHIBITORS AND POLYTHERAPIES FOR THE TREATMENT OF CANCERS |
-
2010
- 2010-06-28 BR BRPI1012675A patent/BRPI1012675A2/pt not_active IP Right Cessation
- 2010-06-28 US US12/824,935 patent/US20100329983A1/en not_active Abandoned
- 2010-06-28 EP EP10791109.1A patent/EP2445932B1/en active Active
- 2010-06-28 JP JP2012516450A patent/JP5836940B2/ja active Active
- 2010-06-28 WO PCT/CA2010/000971 patent/WO2010148501A1/en not_active Ceased
- 2010-06-28 ES ES10791109.1T patent/ES2670588T3/es active Active
- 2010-06-28 MX MX2012000086A patent/MX2012000086A/es not_active Application Discontinuation
- 2010-06-28 CA CA2766272A patent/CA2766272C/en active Active
-
2014
- 2014-12-22 US US14/579,157 patent/US10064964B2/en active Active
-
2018
- 2018-07-26 US US16/046,786 patent/US11090396B2/en active Active
-
2021
- 2021-07-15 US US17/376,670 patent/US12458618B2/en active Active
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