JP2012530714A5 - - Google Patents

Download PDF

Info

Publication number
JP2012530714A5
JP2012530714A5 JP2012516311A JP2012516311A JP2012530714A5 JP 2012530714 A5 JP2012530714 A5 JP 2012530714A5 JP 2012516311 A JP2012516311 A JP 2012516311A JP 2012516311 A JP2012516311 A JP 2012516311A JP 2012530714 A5 JP2012530714 A5 JP 2012530714A5
Authority
JP
Japan
Prior art keywords
sap
variant
seq
amino acid
protomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012516311A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012530714A (ja
JP5822826B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/039043 external-priority patent/WO2010148234A1/en
Publication of JP2012530714A publication Critical patent/JP2012530714A/ja
Publication of JP2012530714A5 publication Critical patent/JP2012530714A5/ja
Application granted granted Critical
Publication of JP5822826B2 publication Critical patent/JP5822826B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012516311A 2009-06-17 2010-06-17 Sap変異体及びその使用 Active JP5822826B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26896109P 2009-06-17 2009-06-17
US61/268,961 2009-06-17
PCT/US2010/039043 WO2010148234A1 (en) 2009-06-17 2010-06-17 Sap variants and their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015090887A Division JP6124943B2 (ja) 2009-06-17 2015-04-27 Sap変異体及びその使用

Publications (3)

Publication Number Publication Date
JP2012530714A JP2012530714A (ja) 2012-12-06
JP2012530714A5 true JP2012530714A5 (enExample) 2015-06-18
JP5822826B2 JP5822826B2 (ja) 2015-11-24

Family

ID=43354870

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012516311A Active JP5822826B2 (ja) 2009-06-17 2010-06-17 Sap変異体及びその使用
JP2015090887A Expired - Fee Related JP6124943B2 (ja) 2009-06-17 2015-04-27 Sap変異体及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015090887A Expired - Fee Related JP6124943B2 (ja) 2009-06-17 2015-04-27 Sap変異体及びその使用

Country Status (10)

Country Link
US (2) US8329659B2 (enExample)
EP (2) EP2987803B1 (enExample)
JP (2) JP5822826B2 (enExample)
AU (1) AU2010262847B2 (enExample)
CA (2) CA2765394C (enExample)
DK (2) DK2987803T3 (enExample)
ES (2) ES2552793T3 (enExample)
HU (2) HUE041034T2 (enExample)
PL (1) PL2987803T3 (enExample)
WO (1) WO2010148234A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9884899B2 (en) 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
CA2754961C (en) * 2009-03-11 2018-04-10 Promedior, Inc. Treatment and diagnostic methods for hypersensitive disorders
EP2405929B1 (en) * 2009-03-11 2018-06-06 Promedior Inc. A sap polypeptide for use in the treatment of autoimmune disorders and graft vs host disease
UA110323C2 (en) * 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
EP2987803B1 (en) 2009-06-17 2018-08-29 Promedior Inc. Sap variants and their use
US20150087576A1 (en) * 2011-12-14 2015-03-26 The Texas A&M University System Compositions associated with and methods of managing neutrophil movement using serum amyloid p (sap)
ES2728446T3 (es) * 2011-12-21 2019-10-24 Promedior Inc Proteínas de fusión de P-anticuerpos de amiloide sérico
RU2020111934A (ru) 2013-10-08 2020-04-29 Промедиор, Инк. Способы лечения фиброзного рака
FR3012453B1 (fr) 2013-10-31 2015-11-13 Lab Francais Du Fractionnement Proteine chimerique dans le traitement de l’amylose
US20180318303A1 (en) * 2015-04-15 2018-11-08 Promedior, Inc. Methods for treating myeloproliferative disorders
CN108114001B (zh) * 2017-12-23 2023-05-30 中国科学院海洋研究所 一种诱导海产双壳贝类产卵的诱导剂及其应用方法
EP3669885A1 (en) * 2018-12-20 2020-06-24 Humanitas Mirasole S.p.A. Use of sap for the treatment of eurotiomycetes fungi infections
CA3196766A1 (en) * 2020-11-02 2022-05-05 Attralus, Inc. Sap fc fusion proteins and methods of use

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023A (en) * 1847-03-20 Stocking-loom
GB1562244A (en) * 1976-11-11 1980-03-05 Lock P M Wound dressing materials
GB1594389A (en) 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
GB8516081D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
US6071517A (en) * 1986-07-07 2000-06-06 Medarex, Inc. Bispecific heteroantibodies with dual effector functions
DE3880647T2 (de) * 1987-11-20 1993-11-18 Kanegafuchi Chemical Ind Sorbentmittel für Serum-Amyloid-Proteine.
US7070994B2 (en) * 1988-03-21 2006-07-04 Oxford Biomedica (Uk) Ltd. Packaging cells
US5272258A (en) 1989-06-29 1993-12-21 Rush-Presbyterian-St. Luke's Medical Center Monoclonal antibodies to C-reactive protein
US5092876A (en) * 1989-08-30 1992-03-03 The United States Of America As Represented By The Department Of Health And Human Services Cell attachment peptides derived from amyloid P component
AU2158292A (en) 1991-05-31 1993-01-08 New England Deaconess Hospital Corporation Cea-binding proteins and methods for their isolation and use
US5591709A (en) * 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
US5654186A (en) * 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US6054121A (en) * 1993-02-26 2000-04-25 The Picower Institute For Medical Research Modulation of immune responses in blood-borne mesenchymal cells
US5804446A (en) * 1993-02-26 1998-09-08 The Picower Institute For Medical Research Blood-borne mesenchymal cells
WO1994027640A1 (en) 1993-05-27 1994-12-08 The Regents Of The University Of Michigan Method of treatment and prevention of immune complex-induced lung injury
US5698589A (en) * 1993-06-01 1997-12-16 International Medical Innovations, Inc. Water-based topical cream containing nitroglycerin and method of preparation and use thereof
GB9317120D0 (en) * 1993-08-17 1993-09-29 Royal Postgrad Med School Human serum amyloid p component
US5981470A (en) 1994-06-07 1999-11-09 The University Of Birmingham Uterine fibroid treatment
US5989811A (en) * 1994-09-29 1999-11-23 Urocor, Inc. Sextant core biopsy predictive mechanism for non-organ confined disease status
US5750345A (en) * 1995-10-31 1998-05-12 Evanston Hospital Corporation Detection of human α-thalassemia mutations and their use as predictors of blood-related disorders
DE69716741T2 (de) 1996-01-25 2003-06-12 Profylakse Aps, Odense Pharmazeutische zusammensetzung, enthaltend serum-amyloid p-komponenten, zur prophylaxe und therapie von viralen infektionen sowie kit zur detektionvon komplexen zwischen solchen zusammensetzungen und viralen komponenten
US6365570B1 (en) * 1997-10-10 2002-04-02 Universiteit Utrecht Pharmaceutical and diagnostic use of Serum Amyloid P component
KR20010041010A (ko) * 1998-02-17 2001-05-15 메다렉스, 인코포레이티드 Fc 수용체 리간드를 사용하여 마크로파지 매개 질환을치료하고 진단하는 방법
CN1235559C (zh) 1998-03-11 2006-01-11 株式会社创研 皮肤水分保持能力的改善剂
JPH11319542A (ja) 1998-05-08 1999-11-24 Tokuyama Corp 超薄層の製造方法
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US6600019B2 (en) * 2000-01-06 2003-07-29 Curagen Corporation Polypeptides and nucleic acids encoding same
EP1267795A1 (en) 2000-03-30 2003-01-02 Brennen Medical Inc. Anti-microbial and immunostimulating composition
US20040068095A1 (en) * 2001-03-14 2004-04-08 Shimkets Richard A. Novel human proteins, polynucleotides encoding them and methods of using the same
US7713705B2 (en) * 2002-12-24 2010-05-11 Biosite, Inc. Markers for differential diagnosis and methods of use thereof
US6872541B2 (en) * 2001-07-25 2005-03-29 Coulter International Corp. Method and compositions for analysis of pentraxin receptors as indicators of disease
US6537811B1 (en) * 2001-08-01 2003-03-25 Isis Pharmaceuticals, Inc. Antisense inhibition of SAP-1 expression
US20030199442A1 (en) 2001-10-09 2003-10-23 Alsobrook John P. Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US7022476B2 (en) * 2002-02-26 2006-04-04 New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof
GB0211136D0 (en) 2002-05-15 2002-06-26 Univ London Treatment and prevention of tissue damage
BR0310084A (pt) * 2002-05-17 2005-02-15 Novartis Ag Composição farmacêutica compreendendo um inibidor de renina, um bloqueador de canal de cálcio e um diurético
GB0216648D0 (en) 2002-07-18 2002-08-28 Lonza Biologics Plc Method of expressing recombinant protein in CHO cells
US8946387B2 (en) 2002-08-14 2015-02-03 Macrogenics, Inc. FcγRIIB specific antibodies and methods of use thereof
DK1534335T4 (en) 2002-08-14 2015-10-05 Macrogenics Inc FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF
US7763256B2 (en) * 2002-12-23 2010-07-27 William Marsh Rice University Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation
US8012472B2 (en) 2002-12-23 2011-09-06 William Marsh Rice University Compositions and methods for suppressing fibrocytes
PT1596880E (pt) 2002-12-23 2011-06-06 Univ Rice William M Métodos e composições para suprimir a diferenciação de fibrócitos
CA2517037A1 (en) 2003-02-27 2004-09-10 Theravision Gmbh Method for reducing levels of c-reactive protein
JP5367982B2 (ja) 2004-04-16 2013-12-11 マクロジェニクス,インコーポレーテッド FcγRIIB特異的抗体とその利用法
CA2565874C (en) 2004-05-10 2017-10-03 Macrogenics, Inc. Humanized fc.gamma.riib-specific antibodies and methods of use thereof
CA2568661A1 (en) 2004-06-03 2006-01-05 Medarex, Inc. Human monoclonal antibodies to fc gamma receptor i (cd64)
WO2006002930A2 (en) 2004-06-30 2006-01-12 Friedrich-Alexander- Universitaet Erlangen- Nuernberg FcϜRIIa POLYMORPHISM AND ITS USE IN DIAGNOSIS
AU2005282720B2 (en) 2004-09-02 2011-08-04 Genentech, Inc. Anti-FC-gamma RIIB receptor antibody and uses therefor
WO2006034373A2 (en) * 2004-09-17 2006-03-30 Biomarin Pharmaceutical Inc. Variants and chemically-modified variants of phenylalanine ammonia-lyase
US7405302B2 (en) 2005-10-11 2008-07-29 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (FLAP) inhibitors
EP1938104A2 (en) 2005-10-17 2008-07-02 Institute for Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
ES2599319T3 (es) 2006-06-26 2017-02-01 Macrogenics, Inc. Anticuerpos específicos de Fc RIIB y métodos de uso de éstos
ES2409756T3 (es) * 2006-12-04 2013-06-27 Promedior, Inc. Combinación de SAP y de enalapril para su uso en tratamiento de trastornos fibróticos o fibroproliferativos
US8497243B2 (en) * 2007-07-06 2013-07-30 Promedior, Inc. Methods and compositions useful in the treatment of mucositis
US9884899B2 (en) * 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
PL2185581T3 (pl) * 2007-07-06 2016-01-29 Promedior Inc Sposoby i kompozycje użyteczne do leczenia zapalenia błony śluzowej
EP2405929B1 (en) * 2009-03-11 2018-06-06 Promedior Inc. A sap polypeptide for use in the treatment of autoimmune disorders and graft vs host disease
CA2754961C (en) * 2009-03-11 2018-04-10 Promedior, Inc. Treatment and diagnostic methods for hypersensitive disorders
JP2012522798A (ja) 2009-04-01 2012-09-27 プロメディオール, インコーポレイテッド 血清アミロイドpの肺および鼻への送達
UA110323C2 (en) * 2009-06-04 2015-12-25 Promedior Inc Derivative of serum amyloid p and their receipt and application
EP2987803B1 (en) * 2009-06-17 2018-08-29 Promedior Inc. Sap variants and their use

Similar Documents

Publication Publication Date Title
JP6124943B2 (ja) Sap変異体及びその使用
JP2012530714A5 (enExample)
US10232014B2 (en) Tear lipocalin muteins binding IL-4 R alpha
JP4344136B2 (ja) アポリポタンパク質類似体
AU2022202225A1 (en) Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
US20100317596A1 (en) Serum amyloid p derivatives and their preparation and use
EP1458758A2 (en) Adiponectin fragments and conjugates
JP2013515474A (ja) 組換え体h因子ならびにそのバリアントおよびコンジュゲート
US20060052292A1 (en) Adiponectin fragments and conjugates
JP2004500100A (ja) 新規化合物
IL282431B1 (en) Cleavable activators of cxcr3 and methods of use
CN110536899A (zh) 对胰岛素受体具有降低的亲和力的胰岛素类似物复合物及其用途
HK1221478B (en) Sap variants and their use
HK1169997B (en) Sap variants and their use