JP2012524781A - 虚血性及び糖尿病性創傷の治癒を促進する組成物、キット及び方法 - Google Patents

虚血性及び糖尿病性創傷の治癒を促進する組成物、キット及び方法 Download PDF

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JP2012524781A
JP2012524781A JP2012507248A JP2012507248A JP2012524781A JP 2012524781 A JP2012524781 A JP 2012524781A JP 2012507248 A JP2012507248 A JP 2012507248A JP 2012507248 A JP2012507248 A JP 2012507248A JP 2012524781 A JP2012524781 A JP 2012524781A
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Prior art keywords
selectin
wound
sdf
protein
subject
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Japanese (ja)
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JP2012524781A5 (enExample
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ヴェラズクエズ,オマイダ,シー.
リウ,ザオ‐ジュン
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University of Miami
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University of Miami
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564Selectins, e.g. CD62
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2012507248A 2009-04-21 2010-04-09 虚血性及び糖尿病性創傷の治癒を促進する組成物、キット及び方法 Pending JP2012524781A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17127109P 2009-04-21 2009-04-21
US61/171,271 2009-04-21
PCT/US2010/030471 WO2010123699A2 (en) 2009-04-21 2010-04-09 Compositions, kits and methods for promoting ischemic and diabetic wound healing

Publications (2)

Publication Number Publication Date
JP2012524781A true JP2012524781A (ja) 2012-10-18
JP2012524781A5 JP2012524781A5 (enExample) 2013-05-30

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JP2012507248A Pending JP2012524781A (ja) 2009-04-21 2010-04-09 虚血性及び糖尿病性創傷の治癒を促進する組成物、キット及び方法

Country Status (6)

Country Link
US (1) US20120058086A1 (enExample)
EP (1) EP2421967A4 (enExample)
JP (1) JP2012524781A (enExample)
KR (1) KR20120023633A (enExample)
CN (1) CN102421894A (enExample)
WO (1) WO2010123699A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516071A (ja) * 2013-03-15 2016-06-02 ユベンタス セラピューティクス,インコーポレイテッド 瘢痕形成を軽減するためのsdf−1の使用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10696974B2 (en) 2014-12-23 2020-06-30 Ilya Pharma Ab Methods for wound healing
US20180028108A1 (en) * 2015-03-18 2018-02-01 Bio1 Systems, Llc Digital wound assessment device and method
CN106581068A (zh) * 2016-11-08 2017-04-26 广州医科大学附属第三医院 一种可以快速恢复皮肤创面的生物膜及其制备方法
KR20200013674A (ko) * 2017-05-02 2020-02-07 유니버시티 오브 마이애미 허혈 조직을 치료하는 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008118370A2 (en) * 2007-03-22 2008-10-02 The Trustees Of The University Of Pennsylvania Hyperbaric treatment in wound healing

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070244043A1 (en) * 2005-03-10 2007-10-18 Novavax, Inc. Recombinant E-selectin made in insect cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008118370A2 (en) * 2007-03-22 2008-10-02 The Trustees Of The University Of Pennsylvania Hyperbaric treatment in wound healing

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6014019975; GALLAGHER K A et al: Journal of the American College of Surgeons , 20030901, S40 *
JPN6014019977; OH II Young et al: Blood vol.110, no.12, 2007, p.3891-3899 *
JPN6014019979; Nishiwaki Y et al: Arterioscler Thromb Vasc Biol. vol.27, no. 3, 200703, p.512-518 *
JPN6014019980; Chen Feng et al: Eur J Pharmacol vol.568, 2007, p.222-230 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516071A (ja) * 2013-03-15 2016-06-02 ユベンタス セラピューティクス,インコーポレイテッド 瘢痕形成を軽減するためのsdf−1の使用

Also Published As

Publication number Publication date
WO2010123699A2 (en) 2010-10-28
CN102421894A (zh) 2012-04-18
EP2421967A2 (en) 2012-02-29
US20120058086A1 (en) 2012-03-08
EP2421967A4 (en) 2013-01-02
KR20120023633A (ko) 2012-03-13
WO2010123699A3 (en) 2011-01-06

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