JP2012524278A - がんの臨床診断および予後診断のためのヒストン修飾パターン - Google Patents
がんの臨床診断および予後診断のためのヒストン修飾パターン Download PDFInfo
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
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- A—HUMAN NECESSITIES
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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| PCT/US2010/031112 WO2010120942A2 (en) | 2009-04-14 | 2010-04-14 | Histone modification patterns for clinical diagnosis and prognosis of cancer |
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| JP2012524278A true JP2012524278A (ja) | 2012-10-11 |
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| JP2016044993A (ja) * | 2014-08-20 | 2016-04-04 | 有限会社マイテック | ヒストン化学修飾判定による癌診断方法 |
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| GB201115095D0 (en) | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| EP2788767B1 (en) | 2011-12-07 | 2017-09-06 | Belgian Volition SPRL | Method for detecting nucleosome adducts |
| GB201303575D0 (en) * | 2013-02-28 | 2013-04-10 | Singapore Volition Pte Ltd | Method for detecting histone modifications in nucleosomes |
| GB201303576D0 (en) * | 2013-02-28 | 2013-04-10 | Singapore Volition Pte Ltd | Method for predicting therapy efficacy using nucleosome structure biomarkers |
| EP3090065B1 (en) * | 2013-12-30 | 2019-12-11 | Agency For Science, Technology And Research | Methods for measuring biomarkers in gastrointestinal cancer |
| EP3213084B2 (en) * | 2014-10-29 | 2023-12-13 | Belgian Volition SPRL | Method for the enrichment of circulating tumor dna |
| WO2016164392A1 (en) | 2015-04-06 | 2016-10-13 | The Johns Hopkins University | A h3t3a mutant protein efficiently reduces h3t3p and causes increased cell death of rapidly dividing cells |
| US10441644B2 (en) | 2015-05-05 | 2019-10-15 | The Regents Of The University Of California | H3.3 CTL peptides and uses thereof |
| US11015226B2 (en) * | 2015-10-06 | 2021-05-25 | Ontario Institute For Cancer Research (Oicr) | Targeting the histone pathway to detect and overcome anthracyclin resistance |
| GB201612815D0 (en) * | 2016-07-25 | 2016-09-07 | Belgian Volition Sa | Novel combination test |
| US20190178894A1 (en) * | 2016-08-09 | 2019-06-13 | B.R.A.H.M.S Gmbh | Histones and/or proadm as markers indicating an adverse event |
| CN108957004B (zh) * | 2018-07-09 | 2021-10-19 | 东南大学 | 检测H3K9me2和H3K36me3表达量的试剂在制备胃癌预后评估试剂盒中的应用 |
| CN110221072B (zh) * | 2019-06-10 | 2022-08-02 | 东南大学 | 检测H3K9甲基化和E-cadherin表达量试剂在制备肝癌预后评估试剂盒的应用 |
| CN112904006B (zh) * | 2021-01-28 | 2022-12-27 | 中山大学 | 一种乳腺癌预后预测分子标志物及其应用 |
| CN120712104A (zh) * | 2022-10-14 | 2025-09-26 | 广东天科雅生物医药科技有限公司 | 针对神经胶质瘤的肽疫苗及其用途 |
| WO2024233383A1 (en) * | 2023-05-05 | 2024-11-14 | University Of Utah Research Foundation | Systems and methods for point-of-care assessment based on pathology image analysis |
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| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| ATE489624T1 (de) * | 2005-04-29 | 2010-12-15 | Univ California | Antikörper gegen histonmodifikationen für die klinische krebsdiagnose und -prognose |
| EP1937837A2 (en) * | 2005-07-29 | 2008-07-02 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
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Cited By (1)
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| JP2016044993A (ja) * | 2014-08-20 | 2016-04-04 | 有限会社マイテック | ヒストン化学修飾判定による癌診断方法 |
Also Published As
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| CA2758933A1 (en) | 2010-10-21 |
| EP2419737A4 (en) | 2013-02-13 |
| EP2419737A2 (en) | 2012-02-22 |
| WO2010120942A3 (en) | 2011-02-24 |
| WO2010120942A2 (en) | 2010-10-21 |
| AU2010236415A1 (en) | 2011-12-01 |
| CN102460173A (zh) | 2012-05-16 |
| US20120094949A1 (en) | 2012-04-19 |
| BRPI1013546A2 (pt) | 2019-04-09 |
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