JP2012524090A5 - - Google Patents
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- Publication number
- JP2012524090A5 JP2012524090A5 JP2012506089A JP2012506089A JP2012524090A5 JP 2012524090 A5 JP2012524090 A5 JP 2012524090A5 JP 2012506089 A JP2012506089 A JP 2012506089A JP 2012506089 A JP2012506089 A JP 2012506089A JP 2012524090 A5 JP2012524090 A5 JP 2012524090A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- trifluoropentanamide
- oxadiazol
- chlorophenyl
- sulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 34
- 125000001766 1,2,4-oxadiazol-3-yl group Chemical group [H]C1=NC(*)=NO1 0.000 claims 11
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 11
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims 11
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 11
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 11
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 11
- FYUWIEKAVLOHSE-UHFFFAOYSA-N ethenyl acetate;1-ethenylpyrrolidin-2-one Chemical compound CC(=O)OC=C.C=CN1CCCC1=O FYUWIEKAVLOHSE-UHFFFAOYSA-N 0.000 claims 6
- FYLZPFSWVMMCQC-UHFFFAOYSA-N 5,5,5-trifluoropentanamide Chemical compound NC(=O)CCCC(F)(F)F FYLZPFSWVMMCQC-UHFFFAOYSA-N 0.000 claims 5
- 239000007962 solid dispersion Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 2
- 238000001694 spray drying Methods 0.000 claims 2
- 238000009474 hot melt extrusion Methods 0.000 claims 1
- 239000012943 hotmelt Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16906609P | 2009-04-14 | 2009-04-14 | |
| US61/169,066 | 2009-04-14 | ||
| PCT/US2010/030679 WO2010120662A2 (en) | 2009-04-14 | 2010-04-12 | Bioavailable compositions of amorphous alpha-(n-sulfonamido)acetamide compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012524090A JP2012524090A (ja) | 2012-10-11 |
| JP2012524090A5 true JP2012524090A5 (enExample) | 2013-03-28 |
Family
ID=42664672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012506089A Pending JP2012524090A (ja) | 2009-04-14 | 2010-04-12 | アモルファスα−（Ｎ−スルホンアミド）アセトアミド化合物の生物学的に利用可能な組成物 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20100261768A1 (enExample) |
| EP (1) | EP2419086B1 (enExample) |
| JP (1) | JP2012524090A (enExample) |
| KR (1) | KR20120027142A (enExample) |
| CN (1) | CN102387788B (enExample) |
| AR (1) | AR076306A1 (enExample) |
| AU (1) | AU2010236701A1 (enExample) |
| BR (1) | BRPI1012523A2 (enExample) |
| CA (1) | CA2758709A1 (enExample) |
| DK (1) | DK2419086T3 (enExample) |
| EA (1) | EA201171207A1 (enExample) |
| ES (1) | ES2426403T3 (enExample) |
| HR (1) | HRP20130807T1 (enExample) |
| MX (1) | MX2011010513A (enExample) |
| NZ (1) | NZ595411A (enExample) |
| PL (1) | PL2419086T3 (enExample) |
| PT (1) | PT2419086E (enExample) |
| SI (1) | SI2419086T1 (enExample) |
| SM (1) | SMT201300106B (enExample) |
| TW (1) | TW201043269A (enExample) |
| WO (1) | WO2010120662A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1289469C (zh) | 2001-12-20 | 2006-12-13 | 布里斯托尔-迈尔斯斯奎布公司 | α－(N－磺酰氨基)乙酰胺衍生物作为β－淀粉样蛋白抑制剂 |
| US8044077B2 (en) | 2009-03-19 | 2011-10-25 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compounds incorporating deuterium as inhibitors of beta amyloid peptide production |
| US7977362B2 (en) | 2009-03-20 | 2011-07-12 | Bristol-Myers Squibb Company | Alpha-(N-benzenesulfonamido)cycloalkyl derivatives |
| US8252821B2 (en) | 2009-04-14 | 2012-08-28 | Bristol-Myers Squibb Company | Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| AR087277A1 (es) * | 2011-07-21 | 2014-03-12 | Bristol Myers Squibb Co | Composiciones biodisponibles de compuestos amorfos de piperidinilo, composicion farmaceutica, metodos |
| US20150045353A1 (en) * | 2013-08-09 | 2015-02-12 | Neurogenetic Pharmaceuticals, Inc. | Formulations containing gamma secretase modulators, methods for preparation and delivery thereof |
| TWI765410B (zh) | 2014-08-08 | 2022-05-21 | 日商中外製藥股份有限公司 | ４環性化合物的非晶質體的用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3999007A (en) * | 1975-10-09 | 1976-12-21 | Carl Joseph Crane | Aircraft visual approach/landing reproducer device and system |
| US5136301A (en) * | 1989-08-30 | 1992-08-04 | Rockwell International Corporation | Primary flight display system having a vertical linear altimeter |
| US5274094A (en) * | 1990-08-15 | 1993-12-28 | British Bio-Technology Limited | Production of heterobicyclic containing benzene sulfonamides |
| GB9202791D0 (en) * | 1992-02-11 | 1992-03-25 | British Bio Technology | Compounds |
| DE69606804T2 (de) * | 1995-06-20 | 2000-06-15 | Honeywell, Inc. | Integriertes System zur Grundkollisionsvermeidung |
| US5977141A (en) * | 1995-11-17 | 1999-11-02 | Warner-Lambert Company | Sulfonamide inhibitors of matrix metalloproteinases |
| US6233522B1 (en) * | 1998-07-06 | 2001-05-15 | Alliedsignal Inc. | Aircraft position validation using radar and digital terrain elevation database |
| US6313123B1 (en) * | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6570531B1 (en) * | 2000-04-27 | 2003-05-27 | Rockwell Collins, Inc. | Satellite navigation receiver designed for compatibility with aircraft automatic landing systems |
| US6483454B1 (en) * | 2000-11-28 | 2002-11-19 | Bae Systems Aerospace Inc. | Close formation aircraft collision avoidance |
| CN1289469C (zh) * | 2001-12-20 | 2006-12-13 | 布里斯托尔-迈尔斯斯奎布公司 | α－(N－磺酰氨基)乙酰胺衍生物作为β－淀粉样蛋白抑制剂 |
| CN101274926A (zh) * | 2003-03-31 | 2008-10-01 | 惠氏公司 | β淀粉样蛋白生成抑制剂含氟和三氟烷基杂环磺酰胺及其衍生物 |
| US20050048112A1 (en) * | 2003-08-28 | 2005-03-03 | Jorg Breitenbach | Solid pharmaceutical dosage form |
| FR2870605B1 (fr) * | 2004-05-18 | 2010-10-08 | Airbus France | Procede et dispositif de guidage automatique d'un aeronef, pour un vol au moins en partie a basse altitude |
| FR2880456B1 (fr) * | 2005-01-03 | 2007-02-23 | Airbus France Sas | Procede et dispositif d'alerte sonore lors de la desactivation d'un pilote automatique d'un aeronef |
| FR2886439B1 (fr) * | 2005-05-24 | 2010-11-05 | Eurocopter France | Procede et dispositif d'aide au pilotage d'un aeronef a basse altitude |
| CN101384250A (zh) * | 2005-11-09 | 2009-03-11 | 诺瓦提斯公司 | 利用临时增塑剂制备药物组合物的方法 |
| FR2897448B1 (fr) * | 2006-02-14 | 2008-03-14 | Airbus France Sas | Procede et systeme d'aide au pilotage d'un aeronef. |
| JP2009528281A (ja) * | 2006-02-17 | 2009-08-06 | ワイス | スルホンアミド置換アルコールおよびその中間体の調製方法 |
| TW200732295A (en) * | 2006-02-17 | 2007-09-01 | Wyeth Corp | Selective N-sulfonylation of 2-amino trifluoroalkyl substituted alcohols |
| WO2007109604A2 (en) * | 2006-03-20 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions |
| US20070218012A1 (en) * | 2006-03-20 | 2007-09-20 | Bittorf Kevin J | Pharmaceutical Compositions |
| FR2911988B1 (fr) * | 2007-01-26 | 2016-03-25 | Airbus France | Procede et dispositif pour determiner une hauteur maximale de stabilisation lors de la phase finale de vol d'un avion |
| US8084477B2 (en) * | 2007-10-31 | 2011-12-27 | Bristol-Myers Squibb Company | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production |
-
2010
- 2010-04-08 TW TW099110918A patent/TW201043269A/zh unknown
- 2010-04-09 US US12/757,304 patent/US20100261768A1/en not_active Abandoned
- 2010-04-12 CA CA2758709A patent/CA2758709A1/en not_active Abandoned
- 2010-04-12 BR BRPI1012523A patent/BRPI1012523A2/pt not_active Application Discontinuation
- 2010-04-12 SI SI201030355T patent/SI2419086T1/sl unknown
- 2010-04-12 JP JP2012506089A patent/JP2012524090A/ja active Pending
- 2010-04-12 NZ NZ595411A patent/NZ595411A/xx not_active IP Right Cessation
- 2010-04-12 MX MX2011010513A patent/MX2011010513A/es unknown
- 2010-04-12 WO PCT/US2010/030679 patent/WO2010120662A2/en not_active Ceased
- 2010-04-12 ES ES10714413T patent/ES2426403T3/es active Active
- 2010-04-12 CN CN2010800160778A patent/CN102387788B/zh not_active Expired - Fee Related
- 2010-04-12 EA EA201171207A patent/EA201171207A1/ru unknown
- 2010-04-12 KR KR1020117024035A patent/KR20120027142A/ko not_active Withdrawn
- 2010-04-12 HR HRP20130807AT patent/HRP20130807T1/hr unknown
- 2010-04-12 PT PT107144131T patent/PT2419086E/pt unknown
- 2010-04-12 EP EP10714413.1A patent/EP2419086B1/en not_active Not-in-force
- 2010-04-12 DK DK10714413.1T patent/DK2419086T3/da active
- 2010-04-12 AU AU2010236701A patent/AU2010236701A1/en not_active Abandoned
- 2010-04-12 PL PL10714413T patent/PL2419086T3/pl unknown
- 2010-04-14 AR ARP100101258A patent/AR076306A1/es unknown
-
2013
- 2013-09-24 SM SM201300106T patent/SMT201300106B/xx unknown
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