JP2012520084A - 非組み込み型レトロウイルスベクターワクチン - Google Patents

非組み込み型レトロウイルスベクターワクチン Download PDF

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JP2012520084A
JP2012520084A JP2011554266A JP2011554266A JP2012520084A JP 2012520084 A JP2012520084 A JP 2012520084A JP 2011554266 A JP2011554266 A JP 2011554266A JP 2011554266 A JP2011554266 A JP 2011554266A JP 2012520084 A JP2012520084 A JP 2012520084A
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vector
protein
virus
hiv
cell
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JP2012520084A5 (enExample
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ボロ ドロプリック
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レンチゲン コーポレイション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/0011Cancer antigens
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    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
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    • A61P31/12Antivirals
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
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    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
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    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6072Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
    • C12N2810/6081Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/48Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
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    • C12N2830/00Vector systems having a special element relevant for transcription
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    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011554266A 2009-03-13 2010-03-13 非組み込み型レトロウイルスベクターワクチン Withdrawn JP2012520084A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US16028509P 2009-03-13 2009-03-13
US61/160,285 2009-03-13
US16676909P 2009-04-05 2009-04-05
US61/166,769 2009-04-05
US16708809P 2009-04-06 2009-04-06
US61/167,088 2009-04-06
PCT/US2010/027262 WO2010105251A2 (en) 2009-03-13 2010-03-13 Non-integrating retroviral vector vaccines

Publications (2)

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JP2012520084A true JP2012520084A (ja) 2012-09-06
JP2012520084A5 JP2012520084A5 (enExample) 2013-04-25

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JP2011554266A Withdrawn JP2012520084A (ja) 2009-03-13 2010-03-13 非組み込み型レトロウイルスベクターワクチン

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US (1) US20120135034A1 (enExample)
EP (1) EP2405945A4 (enExample)
JP (1) JP2012520084A (enExample)
CN (1) CN102438658A (enExample)
CA (1) CA2754603A1 (enExample)
RU (1) RU2012140691A (enExample)
WO (1) WO2010105251A2 (enExample)

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CA2825032A1 (en) * 2011-01-27 2012-08-02 Lentigen Corporation Advanced prime and boost vaccine
JP6143231B2 (ja) 2011-06-10 2017-06-07 ブルーバード バイオ, インコーポレイテッド 副腎脳白質ジストロフィおよび副腎脊髄神経障害のための遺伝子療法ベクター
US9713635B2 (en) * 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
EP2831095B1 (en) * 2012-03-30 2018-11-28 Immune Design Corp. Lentiviral vector particles having improved transduction efficiency for cells expressing dc-sign
US20160175388A1 (en) * 2013-06-15 2016-06-23 Tocagen Inc. Immunosuppressive components associated with retroviral replicating vectors
EP2878674A1 (en) 2013-11-28 2015-06-03 Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) Stable episomes based on non-integrative lentiviral vectors
EP3137100B1 (en) 2014-04-15 2023-12-20 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
MA41382A (fr) * 2015-03-20 2017-11-28 Univ Temple Édition génique basée sur le système crispr/endonucléase à induction par tat
CN107614008A (zh) * 2015-03-20 2018-01-19 蓝鸟生物公司 载体制剂
US11078495B2 (en) 2015-10-15 2021-08-03 The University Of North Carolina At Chapel Hill Methods and compositions for integration defective lentiviral vectors
GB201715052D0 (en) * 2017-09-19 2017-11-01 Oxford Genetics Ltd Vectors
CN111447947B (zh) 2017-12-07 2024-01-12 默沙东有限责任公司 登革病毒疫苗组合物的制剂
RU2680703C1 (ru) * 2018-02-13 2019-02-25 Общество с ограниченной ответственностью "Нанолек" Кассета, предназначенная для получения плазмидных векторов, используемых для создания клеток-продуцентов вирусоподобных частиц (ВПЧ) вируса гриппа
RU2681439C1 (ru) * 2018-02-13 2019-03-06 Общество с ограниченной ответственностью "Нанолек" Вирусоподобная частица вируса гриппа и способ ее получения
RU2680537C1 (ru) * 2018-02-13 2019-02-22 Общество с ограниченной ответственностью "Нанолек" Лентивирусная плазмида (варианты), способ ее получения (варианты), набор праймеров для получения лентивирусного плазмидного вектора (варианты)
RU2681482C1 (ru) * 2018-02-13 2019-03-06 Общество с ограниченной ответственностью "Нанолек" MDCK клетка-продуцент белков вируса гриппа (варианты)
WO2020018715A1 (en) 2018-07-17 2020-01-23 Massachusetts Institute Of Technology Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
JP2022513113A (ja) 2018-11-26 2022-02-07 マサチューセッツ インスティテュート オブ テクノロジー 免疫寛容のための組成物および方法
CN114258398A (zh) 2019-06-13 2022-03-29 总医院公司 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法
BR112023001272A2 (pt) 2020-07-24 2023-04-04 Massachusetts Gen Hospital Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células
AU2022377374A1 (en) * 2021-10-25 2024-05-02 Genvivo, Inc. Compositions and methods for therapeutic or vaccine delivery

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CA2286819A1 (en) * 1997-04-17 1998-10-22 Flossie Wong-Staal Use of lentiviral vectors for antigen presentation in dendritic cells
US5994136A (en) * 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
EP2371955A1 (en) * 2002-09-26 2011-10-05 K.U. Leuven Research & Development Integrase cofactor
GB0225786D0 (en) * 2002-11-05 2002-12-11 Glaxo Group Ltd Vaccine
WO2005023313A1 (en) * 2003-09-09 2005-03-17 Virxsys Corporation Lentivirus vector-based approaches for generating an immune response to hiv humans
EP1675613B1 (en) * 2003-09-15 2012-05-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Hiv vaccines based on env of multiple clades of hiv
FR2872170B1 (fr) * 2004-06-25 2006-11-10 Centre Nat Rech Scient Cnrse Lentivirus non interactif et non replicatif, preparation et utilisations
AU2005309485A1 (en) * 2004-11-24 2006-06-01 Nanovector Limited Viral vectors
EP1858332A4 (en) * 2005-02-16 2011-06-22 Lentigen Corp LENTIVIRUS VECTORS AND ITS USE
GB0526211D0 (en) * 2005-12-22 2006-02-01 Oxford Biomedica Ltd Viral vectors
PT2020444T (pt) * 2007-08-03 2017-08-29 Pasteur Institut Vetores de transferência lentivirais deficientes não integrativos para vacinas

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CA2754603A1 (en) 2010-09-16
WO2010105251A2 (en) 2010-09-16
RU2012140691A (ru) 2014-03-27
EP2405945A4 (en) 2012-09-12
US20120135034A1 (en) 2012-05-31
CN102438658A (zh) 2012-05-02
EP2405945A2 (en) 2012-01-18
WO2010105251A3 (en) 2011-01-27

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