JP2012520084A - 非組み込み型レトロウイルスベクターワクチン - Google Patents

非組み込み型レトロウイルスベクターワクチン Download PDF

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JP2012520084A
JP2012520084A JP2011554266A JP2011554266A JP2012520084A JP 2012520084 A JP2012520084 A JP 2012520084A JP 2011554266 A JP2011554266 A JP 2011554266A JP 2011554266 A JP2011554266 A JP 2011554266A JP 2012520084 A JP2012520084 A JP 2012520084A
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vector
protein
virus
hiv
cell
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JP2012520084A5 (enExample
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ボロ ドロプリック
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レンチゲン コーポレイション
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
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    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
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    • C12N2740/10011Retroviridae
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    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
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    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6072Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
    • C12N2810/6081Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/48Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
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    • C12N2830/00Vector systems having a special element relevant for transcription
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    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011554266A 2009-03-13 2010-03-13 非組み込み型レトロウイルスベクターワクチン Withdrawn JP2012520084A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US16028509P 2009-03-13 2009-03-13
US61/160,285 2009-03-13
US16676909P 2009-04-05 2009-04-05
US61/166,769 2009-04-05
US16708809P 2009-04-06 2009-04-06
US61/167,088 2009-04-06
PCT/US2010/027262 WO2010105251A2 (en) 2009-03-13 2010-03-13 Non-integrating retroviral vector vaccines

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JP2012520084A true JP2012520084A (ja) 2012-09-06
JP2012520084A5 JP2012520084A5 (enExample) 2013-04-25

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JP2011554266A Withdrawn JP2012520084A (ja) 2009-03-13 2010-03-13 非組み込み型レトロウイルスベクターワクチン

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US (1) US20120135034A1 (enExample)
EP (1) EP2405945A4 (enExample)
JP (1) JP2012520084A (enExample)
CN (1) CN102438658A (enExample)
CA (1) CA2754603A1 (enExample)
RU (1) RU2012140691A (enExample)
WO (1) WO2010105251A2 (enExample)

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US20130302368A1 (en) * 2011-01-27 2013-11-14 Boro Dropulic Advanced Prime and Boost Vaccine
CA2838749A1 (en) * 2011-06-10 2012-12-13 Bluebird Bio, Inc. Gene therapy vectors for adrenoleukodystrophy and adrenomyeloneuropathy
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
CN104583231B (zh) * 2012-03-30 2021-02-26 免疫设计公司 具有对表达dc-sign的细胞改善的转导效率的慢病毒载体粒子
JP6640717B2 (ja) * 2013-06-15 2020-02-05 トカジェン インコーポレーテッド レトロウイルス複製ベクターと関連する免疫抑制成分
EP2878674A1 (en) 2013-11-28 2015-06-03 Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) Stable episomes based on non-integrative lentiviral vectors
CA2945816A1 (en) 2014-04-15 2015-10-22 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
US20180094280A1 (en) * 2015-03-20 2018-04-05 Bluebird Bio, Inc. Vector formulations
MA41382A (fr) * 2015-03-20 2017-11-28 Univ Temple Édition génique basée sur le système crispr/endonucléase à induction par tat
WO2017066570A1 (en) * 2015-10-15 2017-04-20 The University Of North Carolina At Chapel Hill Methods and compositions for integration-defective lentiviral vectors
GB201715052D0 (en) * 2017-09-19 2017-11-01 Oxford Genetics Ltd Vectors
BR112020011205A8 (pt) 2017-12-07 2023-02-07 Merck Sharp & Dohme Formulações de composições de vacina contra o vírus da dengue
RU2680537C1 (ru) * 2018-02-13 2019-02-22 Общество с ограниченной ответственностью "Нанолек" Лентивирусная плазмида (варианты), способ ее получения (варианты), набор праймеров для получения лентивирусного плазмидного вектора (варианты)
RU2681439C1 (ru) * 2018-02-13 2019-03-06 Общество с ограниченной ответственностью "Нанолек" Вирусоподобная частица вируса гриппа и способ ее получения
RU2681482C1 (ru) * 2018-02-13 2019-03-06 Общество с ограниченной ответственностью "Нанолек" MDCK клетка-продуцент белков вируса гриппа (варианты)
RU2680703C1 (ru) * 2018-02-13 2019-02-25 Общество с ограниченной ответственностью "Нанолек" Кассета, предназначенная для получения плазмидных векторов, используемых для создания клеток-продуцентов вирусоподобных частиц (ВПЧ) вируса гриппа
WO2020018715A1 (en) 2018-07-17 2020-01-23 Massachusetts Institute Of Technology Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
EP3886759A1 (en) 2018-11-26 2021-10-06 Massachusetts Institute of Technology Compositions and methods for immune tolerance
JP2022536364A (ja) 2019-06-13 2022-08-15 ザ ジェネラル ホスピタル コーポレイション 操作されたヒト内在性ウイルス様粒子および細胞への送達のためのその使用方法
KR20230043151A (ko) 2020-07-24 2023-03-30 더 제너럴 하스피탈 코포레이션 증강된 바이러스-유사 입자 및 세포에의 전달을 위한 그의 사용 방법
CA3235865A1 (en) * 2021-10-25 2023-05-04 Genvivo, Inc. Compositions and methods for therapeutic or vaccine delivery

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WO1998046083A1 (en) * 1997-04-17 1998-10-22 The Regents Of The University Of California Use of lentiviral vectors for antigen presentation in dendritic cells
US5994136A (en) * 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
WO2004029246A2 (en) * 2002-09-26 2004-04-08 K.U.Leuven Research And Development Integrase cofactor
GB0225786D0 (en) * 2002-11-05 2002-12-11 Glaxo Group Ltd Vaccine
EP2055316A1 (en) * 2003-09-09 2009-05-06 VIRxSYS Corporation Lentivirus vector-based approaches for generating an immune response to HIV in humans
CN1913919B (zh) * 2003-09-15 2011-10-19 美国政府健康及人类服务部 基于hiv多进化枝的env的hiv疫苗
FR2872170B1 (fr) * 2004-06-25 2006-11-10 Centre Nat Rech Scient Cnrse Lentivirus non interactif et non replicatif, preparation et utilisations
JP2008521405A (ja) * 2004-11-24 2008-06-26 ナノヴェクター・リミテッド ウイルスベクター
EP2573185A3 (en) * 2005-02-16 2013-06-05 Lentigen Corporation Lentiviral vectors and their use
GB0526211D0 (en) * 2005-12-22 2006-02-01 Oxford Biomedica Ltd Viral vectors
ES2634144T3 (es) * 2007-08-03 2017-09-26 Institut Pasteur Vectores de transferencia lentivíricos defectuosos que no se integran para vacunas

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US20120135034A1 (en) 2012-05-31
WO2010105251A3 (en) 2011-01-27
RU2012140691A (ru) 2014-03-27
CN102438658A (zh) 2012-05-02
CA2754603A1 (en) 2010-09-16
EP2405945A4 (en) 2012-09-12
EP2405945A2 (en) 2012-01-18
WO2010105251A2 (en) 2010-09-16

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