JP2012519043A - 透析装置、透析装置のためのマニホールドおよび方法 - Google Patents
透析装置、透析装置のためのマニホールドおよび方法 Download PDFInfo
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Abstract
Description
Claims (26)
- ダイアライザ(6)と接続されたチューブ(1、5、8)、前記チューブ内に医薬品を送達するための手段および前記チューブおよび前記ダイアライザに通した血液輸送のためのポンプ(11)を含む透析装置であって、前記透析装置は、前記ポンプの吸引作用によって、または前記ポンプの加圧作用によって、または気体もしくは液体の過剰圧によって少なくとも1つの医薬品を投与するための手段(4)を含むことを特徴とする透析装置。
- 前記少なくとも1つの医薬品の総量を投与するために、少なくとも5分間、好ましくは少なくとも10分間が必要とされるように、前記少なくとも1つの医薬品のために前記チューブの1つ内への入口通路の小さな断面積を含む、請求項1に記載の透析装置。
- 前記少なくとも1つの医薬品は、EPO、鉄製剤および/または活性型のビタミンDである、請求項1または2に記載の透析装置。
- 透析を実施するための医薬品を含有する全容器(22、50)は、前記透析装置と同時に接続される、請求項1ないし3項のいずれか一項に記載の透析装置。
- 前記少なくとも1つの医薬品の送達の始動を制御するための制御装置を含む、請求項1ないし4項のいずれか一項に記載の透析装置。
- 医薬品の送達を制御するための少なくとも1つの膜バルブ(30、31、32a、33a)を含む、請求項1ないし5項のいずれか一項に記載の透析装置。
- 少なくとも2つの膜弁および前記少なくとも2つの膜弁のハウジング(30)を越えて伸長する1枚だけの膜(31)を含む、請求項6に記載の透析装置。
- 医薬品の送達を制御するための膜バルブを含み、当該膜バルブは、ハウジング(30)、膜(31)、可動ボルト(32a、32b、32c)および前記ボルトを動かすための電気式、空気圧式、油圧式または磁気手段を含む、請求項1ないし7のいずれか一項に記載の透析装置。
- ポンプの入口側(1a)のチューブと接続された気体を含まない折り畳み式容器(70)(当該容器は医薬品を含む)、または
ポンプの入口側(1a)のチューブと接続された非柔軟性および非折り畳み式容器(当該容器は医薬品および気体を含む)
を含む、請求項1ないし8のいずれか一項に記載の透析装置。 - 前記非柔軟性および非折り畳み式容器は、穿刺可能なゴム栓(52)を備えるバイアル(50)またはシリンジである、請求項9に記載の透析装置。
- 前記シリンジのピストンと気体を含有する容器との接続を含む、請求項10に記載の透析装置。
- 少なくとも1つの医薬品を前記ポンプの加圧作用によって送達するための前記手段は、前記ポンプ(11)の前記出口側のメインライン(20)および前記メインラインを医薬品を含有する容器(22)と接続するためのバイパスライン(21、21a、21b、21c)の第1区間および医薬品を含有する前記容器を前記メインラインと接続するための前記バイパスラインの第2区間(23a、23b、23c)を含む、請求項1ないし11のいずれか一項に記載の透析装置。
- 投与中の前記医薬品の流量を決定する前記断面積は、前記投与が少なくとも5分間、好ましくは少なくとも10分間持続するように設計される、請求項12に記載の透析装置。
- 投与中の前記医薬品の流量を決定する前記断面積は、前記投与が30分間まで、好ましくは20分間まで持続するように設計される、請求項12または13に記載の透析装置。
- 前記メインラインは1つの端部ではダイアライザ(6)および前記他方の端部ではチューブ(1、5)と取り外し可能に接続されている、前記バイパスラインと接続可能な医薬品容器(22)を通した前記メインラインからの流れを提供するためのメインライン(20)およびバイパスライン(21、21a、21b、21c、23a、23b、23c)を含むマニホールド(4)を含む、請求項1ないし14のいずれか一項に記載の透析装置。
- 前記メインラインの前記1つの端部にはダイアライザコネクタ(25)が提供され、前記メインラインの前記他方の端部にはダイアライザコネクタ用の雌アダプタ(26)が用意されている、前記バイパスラインと接続可能な容器(22、50)を通した前記メインラインからの流れを提供するためのメインライン(20)およびバイパスライン(21、21a、21b、21c、23a、23b、23c)を含む、請求項1ないし15のいずれか一項に記載の透析装置のためのマニホールド。
- 前記バイパスラインは、医薬品を含有する容器の入口および出口と接続されている手段を含む、請求項16に記載のマニホールド。
- 少なくとも2つのバイパスライン(21a、21b、21c、23a、23b、23c)を含む請求項16または17に記載にマニホールドであって、各バイバスラインが、各バイパスラインの第1および第2区間を医薬品を含有する容器の入口および出口に接続するための手段を含むことを特徴とする前記マニホールド。
- 医薬品を含有する容器(22)の出口と接続可能な前記バイパスラインの前記第2区間(23a、23b、23c)は、前記メインラインに通じる共通出口ラインを含んでいない、請求項16ないし18のいずれか一項に記載のマニホールド。
- 医薬品を含有する穿刺可能なゴム栓を備えるバイアル(50)またはシリンジ(22)を含む、請求項16ないし19のいずれか一項に記載のマニホールド。
- 前記バイパスラインは、医薬品の投与を始動させるための少なくとも1つの弁(24a、24b、24c、24d、24e、24f)を含む、請求項16ないし20のいずれか一項に記載のマニホールド。
- 好ましくは請求項16ないし21のいずれか一項に記載のマニホールドであって、メインライン、バイパスラインに接続可能な容器を通るメインラインからの流れを提供するためのバイパスラインならびに膜バルブのハウジングおよび膜を含み、他方、膜バルブ用のボルトを含まない、前記マニホールド。
- メインライン、マニホールド内に異なった医薬品容器を挿入するための手段にそれぞれ接続している異なったアダプターおよび各アダプターとメインラインの間の流体接続を含む、好ましくは請求項16ないし22のいずれか一項に記載のマニホールド。
- 前記透析装置の前記血液ポンプの吸引作用または前記血液ポンプの加圧作用または気体もしくは液体の過剰圧による、請求項1〜15のいずれか一項に記載の透析装置によって医薬品を投与する工程を含む、透析方法。
- 前記医薬品の投与は、少なくとも5分間、好ましくは少なくとも10分間持続する、請求項24に記載の方法。
- 前記医薬品は、鉄製剤である、請求項24または25のいずれか一項に記載の方法。
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EPPCT/EP2009/052430 | 2009-03-02 | ||
PCT/EP2009/052430 WO2010099816A1 (en) | 2009-03-02 | 2009-03-02 | Dialysis machine, a manifold for the dialysis machine and process |
PCT/EP2010/052420 WO2010100074A2 (en) | 2009-03-02 | 2010-02-25 | Dialysis machine, a manifold for the dialysis machine and process |
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JP5690284B2 JP5690284B2 (ja) | 2015-03-25 |
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US (1) | US9259524B2 (ja) |
JP (1) | JP5690284B2 (ja) |
CN (1) | CN102341135B (ja) |
AR (1) | AR075707A1 (ja) |
CA (1) | CA2752999C (ja) |
ES (1) | ES2565783T3 (ja) |
PE (1) | PE20100751A1 (ja) |
TW (1) | TW201034708A (ja) |
WO (2) | WO2010099816A1 (ja) |
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CN102652843B (zh) | 2009-07-01 | 2015-09-30 | 弗雷塞尼斯医疗保健控股公司 | 药物输送装置和相关系统以及方法 |
EP2319553A1 (en) * | 2009-11-04 | 2011-05-11 | Fresenius Medical Care Deutschland GmbH | Tubing set having a gate for the connection of vials |
MX356030B (es) | 2011-01-31 | 2018-05-09 | Fresenius Medical Care Holdings Inc | Prevencion de sobre-suministro de farmaco. |
CN106902406B (zh) | 2011-02-08 | 2019-11-08 | 弗雷塞尼斯医疗保健控股公司 | 磁性传感器及相关系统和方法 |
ITBO20110302A1 (it) * | 2011-05-25 | 2012-11-26 | Bellco Srl | Gruppo di infusione di una macchina da dialisi |
WO2013036836A2 (en) | 2011-09-08 | 2013-03-14 | Fresenius Medical Care Holdings, Inc. | System and method of modeling erythropoiesis and its management |
US9144646B2 (en) | 2012-04-25 | 2015-09-29 | Fresenius Medical Care Holdings, Inc. | Vial spiking devices and related assemblies and methods |
US9679111B2 (en) * | 2012-11-05 | 2017-06-13 | Fresenius Medical Care Holdings, Inc. | System and method of modeling erythropoiesis including iron homeostasis |
US9433720B2 (en) * | 2013-03-14 | 2016-09-06 | Fresenius Medical Care Holdings, Inc. | Universal portable artificial kidney for hemodialysis and peritoneal dialysis |
ITUD20130038A1 (it) | 2013-03-20 | 2014-09-21 | Fincantieri Cantieri Navali It | "sistema di movimentazione di elementi tubolari" |
DE102015121356A1 (de) * | 2015-12-08 | 2017-06-08 | Fresenius Medical Care Deutschland Gmbh | Verfahren zum Bestimmen eines Parameters eines flüssigen Medikaments während einer extrakorporalen Blutbehandlung und Blutbehandlungsvorrichtung |
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- 2010-02-25 JP JP2011552395A patent/JP5690284B2/ja not_active Expired - Fee Related
- 2010-02-25 ES ES10707496.5T patent/ES2565783T3/es active Active
- 2010-02-25 US US13/254,284 patent/US9259524B2/en not_active Expired - Fee Related
- 2010-02-25 WO PCT/EP2010/052420 patent/WO2010100074A2/en active Application Filing
- 2010-02-25 CN CN201080010247.1A patent/CN102341135B/zh not_active Expired - Fee Related
- 2010-03-01 PE PE2010000120A patent/PE20100751A1/es not_active Application Discontinuation
- 2010-03-01 TW TW099105800A patent/TW201034708A/zh unknown
- 2010-03-01 AR ARP100100599A patent/AR075707A1/es unknown
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CN102341135A (zh) | 2012-02-01 |
TW201034708A (en) | 2010-10-01 |
CA2752999C (en) | 2017-06-20 |
JP5690284B2 (ja) | 2015-03-25 |
WO2010100074A2 (en) | 2010-09-10 |
CA2752999A1 (en) | 2010-09-10 |
ES2565783T3 (es) | 2016-04-06 |
PE20100751A1 (es) | 2010-11-10 |
US9259524B2 (en) | 2016-02-16 |
AR075707A1 (es) | 2011-04-20 |
WO2010099816A1 (en) | 2010-09-10 |
US20120150141A1 (en) | 2012-06-14 |
CN102341135B (zh) | 2015-09-02 |
WO2010100074A3 (en) | 2010-12-02 |
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